Ependymoma

About the Disease
Benign Ependymoma, also known as ependymoma, is related to spinal cord ependymoma and childhood supratentorial ependymoma, and has symptoms including back pain An important gene associated with Benign Ependymoma is TSC2 (TSC Complex Subunit 2), and among its related pathways/superpathways are Signal Transduction and Disease. The drugs Carboplatin and Cyclophosphamide have been mentioned in the context of this disorder. Affiliated tissues include brain, spinal cord and t cells, and related phenotypes are Decreased viability and Decreased viability

Common Targets
XIRP2 | HPS6 | MSL2 | BCLAF1 | TEKT5 | MAIP1 | CCDC159 | DVL3 | RTF2 | C2orf88 | MTMR4 | RARRES2 | OR2A14 | TMEM37 | G6774 | CLSTN3 | NF2 | RECQL4 | H3-3A | SIL1 | CD36 | VIL1 | SHANK1 | AIFM1 | RALYL | DCLRE1B | LRP6 | CCDC26 | UTP6 | LMF1 | MUC17 | HSPA4L | MYO15A | HDAC2 | SLC26A1 | ADGRB2 | BCAM | TENM2 | XYLB | HRG | SDC1 | TOX3 | PIGM | SEMA6A | NCAN | HDAC6 | SGPP2 | EXO5 | SLC9A1 | DNAJB8 | BTBD3 | POLDIP2 | G1026 | MC1R | GUCY2F | FARS2 | ADAMTSL3 | HSD17B2 | LMO7 | MYO7B | ACTL9 | SLC22A1 | BTBD17 | GTSE1 | OR2T1 | PLXDC1 | LYST | FGF3 | ANXA2R | TEX43 | CCND2 | RGS12 | G29126 | SMG6 | ESPNL | CORO2B | RYR1 | TCF12 | EVI5 | PCDHA3 | PSMD13 | RIPOR2 | CASKIN1 | Protein Kinase B (PKB/Akt) (nonspecified subtype) | PCDH18 | ADAMTS13 | MLPH | FAT4 | GPR137C | LYRM4 | MN1 | PLXNB2 | GPR149 | ZNF358 | CTDNEP1 | CFAP91 | PSMD3 | Phosphatidylinositol 3-kinase (PI3K) (nonspecified subtype) | MYOM2 | ANP32E | G5728 | KMT2C | C8B | JCAD | NLRP8 | STAC | ZC3H12C | GPR52 | SFTPA1 | SERPINI1 | SH2B1 | KIAA0319L | NAT2 | KCNV1 | TRAF4 | OR5P2 | TPMT | PAMR1 | TRMU | MLN | CILP | ANXA11 | FLG | SIPA1L1 | PRKCA | XPOT | ZAN | ESX1 | DDX11 | CCDC107 | C5 | ERICH6B | ITGA8 | TEDC1 | TRMT5 | PRDM15 | KCNA4 | FAN1 | CCDC39 | CNTNAP5 | TTC16 | G1029 | UAP1L1 | MTBP | OCLN | LY9 | PMS2 | DNA Topoisomerase II (nonspecified subtype) | TTLL4 | GLI3 | RASGRF2 | ATP10B | CKAP4 | CCDC169 | NWD1 | TYR | ADCK2 | AP4B1 | ZNF284 | CD180 | TTC28 | PIK3R1 | GRXCR2 | CILP2 | CASR | DISC1 | LRRC4B | SPTA1 | DRD2 | DOCK6 | COL9A1 | TCF4 | CDPF1 | DBNDD1 | KIF27 | ZNF513 | RPGRIP1 | NOD2 | IRS4 | ATP10A | COMT | FAM47A | CDK5RAP1 | NAV1 | NUP42 | ANO8 | TF | HDAC3 | ANKRD23 | ALPK1 | FMO5 | ACKR1 | SH3TC1 | SLC9A3 | SLC12A9 | HDAC1 | HHATL | ATP6V0A2 | SEMA6B | C9orf152 | CDKN2B-AS1 | HNRNPU | FGD6 | LACC1 | PHLDB1 | FGA | ZNF444 | VPS72 | KAT6A | ATAD3B | TMEM117 | CDH8 | TMPRSS11E | PIEZO1 | SOX3 | MKS1 | KCNK10 | HAPLN3 | TPBG | VWDE | PTCH1 | SOD2 | SLFN5 | G7157 | CFAP43 | CASP8 | ADA | PRRX1 | ZFP28 | VAX1 | DNAH6 | GAMT | NPM3 | USP18 | PTPRJ | FOXM1 | PRSS3 | CEP290 | TTC14 | ITGA11 | DTX3L | SMIM2 | FAM193A | IARS1 | SLC4A2 | ZNF526 | CYP4F22 | TULP1 | SYBU | BBS5 | GPAM | STAT5 (nonspecified subtype) | CCDC28B | FUCA1 | SMURF1 | TFAP2A | BIN3 | LOXL1 | CTSZ | HRNR | WDR43 | RNMT | PRKCH | XRCC3 | SLC22A15 | INTS2 | ACHE | PLA2G4D | R3HDM1 | LRRC36 | PCSK7 | UNC13C | ANO2 | C11orf40 | DICER1 | DNHD1 | UBP1 | CDK17 | DSP | LRRC17 | SIGLEC1 | ACSL6 | PUM2 | ANKRD11 | GSDMB | NMBR | PRB1 | STT3A | ACVR1 | USP54 | EVX1 | PTPN18 | HAVCR1 | KANK3 | CKAP2 | RTEL1 | ARHGEF17 | LINC02693 | AKIP1 | MYOM1 | PNKP | ANKS3 | ADRB1 | LRP1 | PNP | FKBP9 | Mitogen-Activated Protein Kinase (nonspecified subtype) | EPYC | PLEKHG5 | GPAT2 | SORCS2 | KMT2A | G2033 | H3C3 | AMPH | ASCL3 | IFNE | SOAT1 | TNS2 | RP1 | AOC1 | ELL3 | ACOXL | RASSF8 | CCL27 | COL6A1 | PDLIM4 | FGF23 | CHIA | DENND1C | CDC14B | MAPK15 | AMDHD1 | ABCC6 | G2064 | CABP4 | ACSM1 | DCTN1 | MRI1 | TECPR1 | TDRD6 | FSIP2 | F5 | SI | SLC22A4 | MARS1 | MSRB3 | CXCR6 | COG6 | LPIN2 | DAPK3 | MEFV | NELFA | ZNF235 | USH2A | KDM6B | CLPP | MCHR2 | ANKZF1 | TCHH | NOS3 | POLR2A | Janus Kinase (nonspecified subtype) | IL16 | NEFH | MMP2 | FAM118A | BSN | KIFC1 | HYDIN | GIN1 | MAN2A2 | SLC17A5 | CNGB1 | PLA2R1 | TRPS1 | CA14 | BLTP3A | PCARE | AHNAK2 | KIR3DL3 | TTN | SPATS2L | PKD1L2 | PTCHD1 | FURIN | PDE5A | UNC80 | POLR1B | VCX | SLC38A10 | KCTD10 | POLR2D | PRG2 | PYCR2 | LZTS3 | SLC10A2 | CYP2B6 | APOL1 | SCN1B | USE1 | CDAN1 | LRP2 | NGLY1 | ZNF610 | MGMT | CALR | PLXNB1 | MAGEF1 | C3 | RFX6 | GBA2 | OR6C4 | IL10 | AKAP8 | FGD2 | EPHX1 | TRIM32 | PGGT1B | CDH5 | FAAP20 | OTC | CFTR | CEP350 | TAP1 | TTLL12 | APBA1 | KLKB1 | OR7E24 | G1956 | MYCN | CFAP410 | TANGO6 | ARRDC1-AS1 | DCST2 | PEAR1 | CYP1B1 | SH3D21 | USP9X | FMO3 | QRICH2 | VPS13C | TSR1 | COL27A1 | CYP4A11 | NMRK2 | ABO | WDFY4 | TTC3 | PEX6 | POLR2E | IGF2BP2 | COL2A1 | DDX3X | CADPS2 | ADRA1B | MYH7B | C9orf43 | MTUS2 | VPS28 | FRS2 | OR4S2 | BEX1 | APC | LGALS1 | DRD3 | CD276 | CABP1 | ADCY9 | SLC10A4 | TMEM151A | N4BP2 | COPB2 | E2F8 | KANK2 | MRTFA | MUC20 | CC2D2A | TUSC1 | HECW2 | KCNH7 | ARSH | THOC5 | G596 | TUBAL3 | CBLB | CDH23 | EMX2 | NLRP12 | INF2 | OR6B2 | MLH1 | TXK | PAICS | JAK3 | RAB11FIP5 | RASSF2 | FCRL5 | OR5L1 | CACNA1F | RTEL1-TNFRSF6B | JHY | KNDC1 | CD68 | SETD3 | HLA-C | PNLIPRP2 | MFSD6 | PLSCR2 | AOAH | ITGB6 | GOLGA4 | AHRR | ROBO3 | G7015 | OR5M9 | MYBPH | GIGYF2 | GOLGB1 | SYTL2 | ARID3C | DNAH10 | ALOX15 | LATS2 | CR2 | WNT4 | TUBB | FMN2 | RAPGEF5 | LLGL2 | ERCC5 | RAD51AP2 | MINAR1 | EDC4 | OR51G2 | FHOD3 | INPP5J | CDKL4 | HEXIM2 | EBLN2 | MACROD2 | KDM6A | OSBP2 | OR9G1 | NCOR1 | MFAP1

Note: If you'd like to get a target analysis report for Ependymoma, or if you are interested to learn how our AI-powered BDE-Chem can design therapeutic molecules to interact with the target(s) above against the disease of Ependymoma at a cost 90% lower than traditional approaches, please feel free to contact us at BD@silexon.ai.

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