Ependymoma

About the Disease
Benign Ependymoma, also known as ependymoma, is related to spinal cord ependymoma and childhood supratentorial ependymoma, and has symptoms including back pain An important gene associated with Benign Ependymoma is TSC2 (TSC Complex Subunit 2), and among its related pathways/superpathways are Signal Transduction and Disease. The drugs Carboplatin and Cyclophosphamide have been mentioned in the context of this disorder. Affiliated tissues include brain, spinal cord and t cells, and related phenotypes are Decreased viability and Decreased viability

Common Targets
XIRP2 | HPS6 | MSL2 | BCLAF1 | TEKT5 | MAIP1 | CCDC159 | DVL3 | RTF2 | C2orf88 | MTMR4 | RARRES2 | OR2A14 | TMEM37 | G6774 | CLSTN3 | NF2 | RECQL4 | H3-3A | SIL1 | CD36 | VIL1 | SHANK1 | AIFM1 | RALYL | DCLRE1B | LRP6 | CCDC26 | UTP6 | LMF1 | MUC17 | HSPA4L | MYO15A | HDAC2 | SLC26A1 | ADGRB2 | BCAM | TENM2 | XYLB | HRG | SDC1 | TOX3 | PIGM | SEMA6A | NCAN | HDAC6 | SGPP2 | EXO5 | SLC9A1 | DNAJB8 | BTBD3 | POLDIP2 | G1026 | MC1R | GUCY2F | FARS2 | ADAMTSL3 | HSD17B2 | LMO7 | MYO7B | ACTL9 | SLC22A1 | BTBD17 | GTSE1 | OR2T1 | PLXDC1 | LYST | FGF3 | ANXA2R | TEX43 | CCND2 | RGS12 | G29126 | SMG6 | ESPNL | CORO2B | RYR1 | TCF12 | EVI5 | PCDHA3 | PSMD13 | RIPOR2 | CASKIN1 | Protein Kinase B (PKB/Akt) (nonspecified subtype) | PCDH18 | ADAMTS13 | MLPH | FAT4 | GPR137C | LYRM4 | MN1 | PLXNB2 | GPR149 | ZNF358 | CTDNEP1 | CFAP91 | PSMD3 | Phosphatidylinositol 3-kinase (PI3K) (nonspecified subtype) | MYOM2 | ANP32E | G5728 | KMT2C | C8B | JCAD | NLRP8 | STAC | ZC3H12C | GPR52 | SFTPA1 | SERPINI1 | SH2B1 | KIAA0319L | NAT2 | KCNV1 | TRAF4 | OR5P2 | TPMT | PAMR1 | TRMU | MLN | CILP | ANXA11 | FLG | SIPA1L1 | PRKCA | XPOT | ZAN | ESX1 | DDX11 | CCDC107 | C5 | ERICH6B | ITGA8 | TEDC1 | TRMT5 | PRDM15 | KCNA4 | FAN1 | CCDC39 | CNTNAP5 | TTC16 | G1029 | UAP1L1 | MTBP | OCLN | LY9 | PMS2 | DNA Topoisomerase II (nonspecified subtype) | TTLL4 | GLI3 | RASGRF2 | ATP10B | CKAP4 | CCDC169 | NWD1 | TYR | ADCK2 | AP4B1 | ZNF284 | CD180 | TTC28 | PIK3R1 | GRXCR2 | CILP2 | CASR | DISC1 | LRRC4B | SPTA1 | DRD2 | DOCK6 | COL9A1 | TCF4 | CDPF1 | DBNDD1 | KIF27 | ZNF513 | RPGRIP1 | NOD2 | IRS4 | ATP10A | COMT | FAM47A | CDK5RAP1 | NAV1 | NUP42 | ANO8 | TF | HDAC3 | ANKRD23 | ALPK1 | FMO5 | ACKR1 | SH3TC1 | SLC9A3 | SLC12A9 | HDAC1 | HHATL | ATP6V0A2 | SEMA6B | C9orf152 | CDKN2B-AS1 | HNRNPU | FGD6 | LACC1 | PHLDB1 | FGA | ZNF444 | VPS72 | KAT6A | ATAD3B | TMEM117 | CDH8 | TMPRSS11E | PIEZO1 | SOX3 | MKS1 | KCNK10 | HAPLN3 | TPBG | VWDE | PTCH1 | SOD2 | SLFN5 | G7157 | CFAP43 | CASP8 | ADA | PRRX1 | ZFP28 | VAX1 | DNAH6 | GAMT | NPM3 | USP18 | PTPRJ | FOXM1 | PRSS3 | CEP290 | TTC14 | ITGA11 | DTX3L | SMIM2 | FAM193A | IARS1 | SLC4A2 | ZNF526 | CYP4F22 | TULP1 | SYBU | BBS5 | GPAM | STAT5 (nonspecified subtype) | CCDC28B | FUCA1 | SMURF1 | TFAP2A | BIN3 | LOXL1 | CTSZ | HRNR | WDR43 | RNMT | PRKCH | XRCC3 | SLC22A15 | INTS2 | ACHE | PLA2G4D | R3HDM1 | LRRC36 | PCSK7 | UNC13C | ANO2 | C11orf40 | DICER1 | DNHD1 | UBP1 | CDK17 | DSP | LRRC17 | SIGLEC1 | ACSL6 | PUM2 | ANKRD11 | GSDMB | NMBR | PRB1 | STT3A | ACVR1 | USP54 | EVX1 | PTPN18 | HAVCR1 | KANK3 | CKAP2 | RTEL1 | ARHGEF17 | LINC02693 | AKIP1 | MYOM1 | PNKP | ANKS3 | ADRB1 | LRP1 | PNP | FKBP9 | Mitogen-Activated Protein Kinase (nonspecified subtype) | EPYC | PLEKHG5 | GPAT2 | SORCS2 | KMT2A | G2033 | H3C3 | AMPH | ASCL3 | IFNE | SOAT1 | TNS2 | RP1 | AOC1 | ELL3 | ACOXL | RASSF8 | CCL27 | COL6A1 | PDLIM4 | FGF23 | CHIA | DENND1C | CDC14B | MAPK15 | AMDHD1 | ABCC6 | G2064 | CABP4 | ACSM1 | DCTN1 | MRI1 | TECPR1 | TDRD6 | FSIP2 | F5 | SI | SLC22A4 | MARS1 | MSRB3 | CXCR6 | COG6 | LPIN2 | DAPK3 | MEFV | NELFA | ZNF235 | USH2A | KDM6B | CLPP | MCHR2 | ANKZF1 | TCHH | NOS3 | POLR2A | Janus Kinase (nonspecified subtype) | IL16 | NEFH | MMP2 | FAM118A | BSN | KIFC1 | HYDIN | GIN1 | MAN2A2 | SLC17A5 | CNGB1 | PLA2R1 | TRPS1 | CA14 | BLTP3A | PCARE | AHNAK2 | KIR3DL3 | TTN | SPATS2L | PKD1L2 | PTCHD1 | FURIN | PDE5A | UNC80 | POLR1B | VCX | SLC38A10 | KCTD10 | POLR2D | PRG2 | PYCR2 | LZTS3 | SLC10A2 | CYP2B6 | APOL1 | SCN1B | USE1 | CDAN1 | LRP2 | NGLY1 | ZNF610 | MGMT | CALR | PLXNB1 | MAGEF1 | C3 | RFX6 | GBA2 | OR6C4 | IL10 | AKAP8 | FGD2 | EPHX1 | TRIM32 | PGGT1B | CDH5 | FAAP20 | OTC | CFTR | CEP350 | TAP1 | TTLL12 | APBA1 | KLKB1 | OR7E24 | G1956 | MYCN | CFAP410 | TANGO6 | ARRDC1-AS1 | DCST2 | PEAR1 | CYP1B1 | SH3D21 | USP9X | FMO3 | QRICH2 | VPS13C | TSR1 | COL27A1 | CYP4A11 | NMRK2 | ABO | WDFY4 | TTC3 | PEX6 | POLR2E | IGF2BP2 | COL2A1 | DDX3X | CADPS2 | ADRA1B | MYH7B | C9orf43 | MTUS2 | VPS28 | FRS2 | OR4S2 | BEX1 | APC | LGALS1 | DRD3 | CD276 | CABP1 | ADCY9 | SLC10A4 | TMEM151A | N4BP2 | COPB2 | E2F8 | KANK2 | MRTFA | MUC20 | CC2D2A | TUSC1 | HECW2 | KCNH7 | ARSH | THOC5 | G596 | TUBAL3 | CBLB | CDH23 | EMX2 | NLRP12 | INF2 | OR6B2 | MLH1 | TXK | PAICS | JAK3 | RAB11FIP5 | RASSF2 | FCRL5 | OR5L1 | CACNA1F | RTEL1-TNFRSF6B | JHY | KNDC1 | CD68 | SETD3 | HLA-C | PNLIPRP2 | MFSD6 | PLSCR2 | AOAH | ITGB6 | GOLGA4 | AHRR | ROBO3 | G7015 | OR5M9 | MYBPH | GIGYF2 | GOLGB1 | SYTL2 | ARID3C | DNAH10 | ALOX15 | LATS2 | CR2 | WNT4 | TUBB | FMN2 | RAPGEF5 | LLGL2 | ERCC5 | RAD51AP2 | MINAR1 | EDC4 | OR51G2 | FHOD3 | INPP5J | CDKL4 | HEXIM2 | EBLN2 | MACROD2 | KDM6A | OSBP2 | OR9G1 | NCOR1 | MFAP1

Note: If you'd like to get a target analysis report for Ependymoma, or if you are interested to learn how our AI-powered BDE-Chem can design therapeutic molecules to interact with the target(s) above against the disease of Ependymoma at a cost 90% lower than traditional approaches, please feel free to contact us at BD@silexon.tech.

Other Diseases

Oculocutaneous Albinism Type 4 | Jawad Syndrome | Corneal Ulcer | Sarcoma, Ewing | Arteriovenous Malformations | Acute Motor Axonal Neuropathy | Neurodevelopmental Disorders | Sotos Syndrome | Glutathione Synthetase Deficiency | Heterotopic Ossification | Guttate Psoriasis | 3-hydroxy-3-methylglutaryl-CoA Synthase Deficiency | Growth Hormone Excess | 3-methylglutaconic Aciduria | Dental Caries | Renal Failure | Trimethylaminuria | Histoplasmosis | Angioimmunoblastic T-cell Lymphoma | Cholangitis | Pericarditis | Sclerosing Cholangitis | Low Tension Glaucoma | Alveolar Capillary Dysplasia | Urea Cycle Disorder | Congenital Myopathy | Robinow Syndrome | Heroin Dependence | Pelvic Inflammatory Disease | POEMS Syndrome | Pulmonary Vein Stenosis | Cryptorchidism | Choriocarcinoma | Encephalitis | Encephalopathy, Hepatic | Pulmonary Veno-occlusive Disease | Fibrodysplasia Ossificans Progressiva | Glycogen Storage Disease Type 1a | Partington Syndrome | Dermatitis Herpetiformis | LMNA-related Congenital Muscular Dystrophy | Encephalopathy, Ethylmalonic | Muscle Wasting | Neurodevelopmental Disorder With Central Hypotonia And Dysmorphic Facies | Diabetes Gestational | Alpha-thalassemia Myelodysplasia Syndrome | CHARGE Syndrome | Glomerulonephritis, Membranous | Pleurisy | Multifocal Motor Neuropathy | Craniometaphyseal Dysplasia | Harlequin Ichthyosis | Vogt-Koyanagi-Harada Syndrome | Sulfite Oxidase Deficiency | Actinomycetoma | Thrombocythemia, Essential | Chromosome 9q34.3 Deletion Syndrome | Hereditary Multiple Exostoses | Axenfeld-Rieger Syndrome | Congenital Nystagmus | Autosomal Recessive Spastic Paraplegia Type 54 | Anosmia, Congenital | Neurofibromatosis-Noonan Syndrome | Sarcoma, Endometrial Stromal | Bardet-Biedl Syndrome | Krabbe Disease | Bietti Crystalline Dystrophy | Asperger Syndrome | Primary Aldosteronism | Myoclonic Epilepsy With Ragged Red Fibers | Neurocutaneous Syndromes | Diabetes Insipidus, Nephrogenic | Macular Corneal Dystrophy | Cholestasis | Hereditary Hemorrhagic Telangiectasia Type 2 | Cerebral Cavernous Malformations | Gastroenteritis | Liebenberg Syndrome | Traboulsi Syndrome | Schaaf-Yang Syndrome | Hemochromatosis | Malaria, Cerebral | Isobutyryl-CoA Dehydrogenase Deficiency | Metachondromatosis | Deafness, Dystonia, And Cerebral Hypomyelination | Liver Failure | Central Pain Syndrome | Thrombotic Microangiopathy | Wilson's Disease | Episodic Ataxia | Graft-versus-host Disease | Hepatitis D | Gangliosidosis, GM1 | Blepharitis | Renal-hepatic-pancreatic Dysplasia | Chronic Idiopathic Myelofibrosis | Skin Fragility-woolly Hair Syndrome | Epidermolysis Bullosa | McKusick Type Metaphyseal Chondrodysplasia | Split Hand-foot Malformation | Asthma, Exercise-induced | Pheochromocytoma | Lymphoma Lymphoblastic | Donnai-Barrow Syndrome | Spinocerebellar Ataxia Type 17 | Autosomal Recessive Bestrophinopathy | 6-pyruvoyl-tetrahydropterin Synthase Deficiency | Viral Meningitis | Osteoglophonic Dysplasia | Nutrition Disorders | Colitis | Presbycusis | Bainbridge-Ropers Syndrome | Cryoglobulinemia | Zimmermann-Laband Syndrome | Iron Metabolism Disorders | Proteasome-associated Autoinflammatory Syndrome 2 | Pierson Syndrome | Arrhythmogenic Right Ventricular Cardiomyopathy | Schnitzler Syndrome | C3 Glomerulonephritis | Congenital Disorders Of Glycosylation Type II | Sandhoff Disease | Usher Syndrome Type IIC | Hyperbilirubinemia | Clouston Hidrotic Ectodermal Dysplasia | Mountain Sickness | Phenylketonuria II | Bare Lymphocyte Syndrome | Sepiapterin Reductase Deficiency | Pierre Robin Syndrome | Lewy Body Dementia | Haim-Munk Syndrome | Myelitis | Fibromuscular Dysplasia | Succinic Semialdehyde Dehydrogenase Deficiency | Bloom Syndrome | Mastitis | Allan-Herndon-Dudley Syndrome | Generalized Epilepsy And Paroxysmal Dyskinesia | Netherton Syndrome | Tenosynovial Giant Cell Tumor | Alkaptonuria | Blastoma, Pleuropulmonary | Fahr Disease | Combined Pituitary Hormone Deficiency | Cholecystitis | Cancer, Skin | Androgenic Alopecia | Heart Septal Defects | Focal Facial Dermal Dysplasia | Uterine Leiomyoma | Dominant Optic Atrophy | Hemochromatosis Type 1 | Progressive Encephalopathy-optic Atrophy Syndrome | Ebstein Anomaly | Alopecia | Hemophagocytic Lymphohistiocytosis | Common Variable Immunodeficiency | Stromal Corneal Dystrophy | Fontaine Progeroid Syndrome | Imerslund-Grasbeck Syndrome | PHARC Syndrome | Moyamoya Disease | Budd-Chiari Syndrome | Peritonitis | Spinocerebellar Ataxia Type 13 | Familial Glucocorticoid Deficiency | Coronary Heart Disease | Alpha-1 Antitrypsin Deficiency | Hepatitis, Alcoholic | Cancer, Colon | Epidermolytic Palmoplantar Keratoderma | Steel Syndrome | Idiopathic Pulmonary Fibrosis | Azoospermia | Pneumonia, Bacterial | Bernard-Soulier Syndrome | Tic Disorder | Sporadic Inclusion Body Myositis | D-2-Hydroxyglutaric Aciduria | Myositis | Multicentric Carpotarsal Osteolysis Syndrome | Avian Influenza | Basal Cell Nevus Syndrome | Blepharophimosis Syndrome | Rotor Syndrome | Spinocerebellar Ataxia Type 16 | Ophthalmoplegia | Primary Torsion Dystonia | Hepatitis, Autoimmune | Hyperuricemia | Rhabdomyosarcoma, Embryonal | Tinea Versicolor | Antiphospholipid Syndrome | Saethre-Chotzen Syndrome | Pemphigus | Prostatitis | Thin Basement Membrane Disease | Camptocormia | Atopy | Long QT Syndrome Type 3 | Unverricht-Lundborg Syndrome | Protein S Deficiency | Vitamin K Deficiency | Meniere's Disease | Benign Hereditary Chorea | Behcet's Disease | Pneumococcal Meningitis | Osteitis | Epidermolysis Bullosa Acquisita | Smith-Kingsmore Syndrome | Myasthenia Gravis | Pancreatitis | Cabezas Syndrome | Crohn's Disease | Hypohidrotic Ectodermal Dysplasia | Keratocystic Odontogenic Tumor | Atelosteogenesis Type 1 | Thrombasthenia | Urolithiasis | Acquired Partial Lipodystrophy | Lentigo | Argininosuccinic Aciduria | Ellis-Van Creveld Syndrome | Duane Retraction Syndrome | Pseudoexfoliation Syndrome | Schamberg Disease | Renal Hypomagnesemia 3 | Leukoplakia | Sarcoma, Alveolar Soft Part | Persistent Mullerian Duct Syndrome | Histiocytic Sarcoma | Aldosterone Deficiency | Congenital Central Hypoventilation Syndrome | Gardner Syndrome | GATA2 Deficiency | Retinal Detachment | Glomerulonephritis | McLeod Syndrome | Goiter | Spinocerebellar Ataxia Type 28 | Pilomatrix Carcinoma | Fuchs Dystrophy | Aicardi-Goutieres Syndrome | Roberts Syndrome | Sarcoidosis | Hepatitis E | Marfan Syndrome | Pontocerebellar Hypoplasia Type 7 | Neuroleptic Malignant Syndrome | Chondroma | Neural Tube Defect | Hepatorenal Syndrome | Hereditary Neuropathy With Liability To Pressure Palsies | Hyperthyroidism | Pseudohermaphroditism | Open-angle Glaucoma | Zygomycosis | Trichotillomania | Myotonic Disorders | Pernicious Anemia | Diffuse Mesangial Sclerosis | Postpartum Depression | Mucormycosis | Frontotemporal Dementia With Amyotrophic Lateral Sclerosis | Diabetes | Chronic Lymphocytic Leukemia | Stroke, Ischemic | Familial Hypertrophic Cardiomyopathy | Adenylosuccinate Lyase Deficiency | Creatine Deficiency Syndrome Due To AGAT Deficiency | Aneurysm, Abdominal Aortic | Keratosis, Seborrheic | Epicondylitis | Multiple Mitochondrial Dysfunctions Syndrome Type 1 | Amyotrophic Lateral Sclerosis, Juvenile | Influenza | Alstrom Syndrome | Cole-Carpenter Syndrome | Tendinitis | 5-oxoprolinase Deficiency | Impulse Control Disorder | Prolymphocytic Leukemia | Plasma Cell Leukemia | Acute Anterior Uveitis | Lyme Disease | Temtamy Preaxial Brachydactyly Syndrome | Prurigo Nodularis | HUPRA Syndrome | Uveitis, Anterior | Urofacial Syndrome | Uremia | Glycogen Storage Disease Type 0 | Galactosialidosis | Colorectal Adenoma | Infertility, Male | Wiskott-Aldrich Syndrome | Birt-Hogg-Dube Syndrome | Carotid Artery Disease | Anorectal Fistula | Low Phospholipid Associated Cholelithiasis | Hyper IgE Syndrome | Autosomal Recessive Congenital Ichthyosis | Personality Disorders | Nephropathy | Hidradenitis Suppurativa | Acute Lung Injury | Fanconi Anemia | Lymphoma, AIDS-related | Methemoglobinemia | Muscular Dystrophy | Acute Generalized Exanthematous Pustulosis | Mucolipidosis Type II | Vitamin B12 Deficiency | Glycogen Storage Disease | Adenoma, Pleomorphic | Keratosis | Pseudo-pseudohypoparathyroidism | Osteonecrosis Of The Jaw | Usher Syndrome Type II | Glanzmann Thrombasthenia | Mitochondrial DNA Depletion Syndrome, Hepatocerebral Form | Nasodigitoacoustic Syndrome | Achondrogenesis | Hyperphosphatasia With Intellectual Disability Syndrome 4 | Autonomic Neuropathy | Large Granular Lymphocytic Leukemia | Bleeding Disorder Due To CalDAG-GEFI Deficiency | Exfoliative Dermatitis | Galactosemia | Oculodentodigital Dysplasia | X-linked Myotubular Myopathy | Hypertension, Renal | Benign Familial Infantile Seizures | Rhabdomyosarcoma | Benign Familial Pemphigus | Hypomyelination With Atrophy Of Basal Ganglia And Cerebellum | Dyskeratosis Congenita | Xeroderma Pigmentosum Variant Type | Periventricular Nodular Heterotopia | Periodic Limb Movement Disorder | Vulvovaginitis | Lymphoma, B-cell | Cholestasis, Intrahepatic | Retinal Vasculitis | Spondyloepiphyseal Dysplasia Tarda, X-linked | Tonsillitis | Endometritis | Juvenile Polyposis | Renal Hypouricemia | Chondrodysplasia Punctata 2, X-linked Dominant | Hyperinsulinemic Hypoglycemia | Nephrotic Syndrome | Neuromuscular Disorders | Hypobetalipoproteinemias | Episodic Ataxia Type 2 | Migraine | Hemolytic Anemia | Multiple Myeloma | Neurocysticercosis | Goiter, Nodular | Stevens-Johnson Syndrome | Gaucher Disease | Acute Kidney Injury | Graves Disease | VACTERL Association | Hemorrhagic Disorders | Primary Familial Brain Calcification | Pycnodysostosis | Glioblastoma Multiforme | Tyrosinemia | Milk Allergy | Corneal Edema | Hamartoma | Congenital Stationary Night Blindness | Inborn Errors Of Metabolism | Eclampsia | Holt-Oram Syndrome | Histiocytosis | Adrenal Insufficiency | Lipid Storage Diseases | Chiari Malformation Type I | Giant Axonal Neuropathy | Charcot-Marie-Tooth Disease Type 4E | Myhre Syndrome | Chronic Inflammatory Demyelinating Polyneuropathy | Pyloric Stenosis, Infantile Hypertrophic | Urticaria | Sleep Disorder | Schizoaffective Disorder | Pontocerebellar Hypoplasia Type 2 | Overactive Bladder | Central Retinal Artery Occlusion | Spinocerebellar Ataxia Type 10 | X-linked Acrogigantism | Hypotension, Orthostatic | Neurofibrosarcoma | Carcinoma, Transitional Cell | 3-methylglutaconic Aciduria Type I