Primary Ovarian Insufficiency

About the Disease
Premature Menopause, also known as primary ovarian insufficiency, is related to perrault syndrome and amenorrhea, and has symptoms including pelvic pain An important gene associated with Premature Menopause is STAG3 (Stromal Antigen 3), and among its related pathways/superpathways is DNA Damage. The drugs Estradiol and Polyestradiol phosphate have been mentioned in the context of this disorder. Affiliated tissues include ovary, bone marrow and thyroid, and related phenotypes are Decreased substrate adherent cell growth and Decreased substrate adherent cell growth

Common Targets
RECQL4 | LLGL1 | SYCP1 | PMM2 | KIT | HROB | C15orf40 | IGSF10 | SMC1B | FANCD2 | BDP1 | PRMT6 | ADAMTSL3 | DCAF17 | USP36 | NINL | CENPI | G207 | ORC6 | C14orf39 | HARS2 | LARS2 | GATA4 | KHDRBS1 | SOHLH1 | NEK8 | NXF5 | INSL3 | PNPLA7 | BMP8B | WDR62 | HSD17B4 | MCM9 | COL4A6 | PRDM1 | DMC1 | SYDE2 | BRCA2 | BUB1B | XPNPEP2 | MSH4 | FSHR | LCK | UBR4 | PADI6 | MUTYH | ESR2 | SYCP2L | BOD1L1 | TG | MSH5 | PRKD1 | TBPL2 | USP53 | TDRD9 | SSH1 | MRPS22 | POU5F1 | PSMC3IP | POLR3H | APLF | CENPF | MND1 | TP63 | CYP2E1 | NR5A1 | INHA | SOX3 | NTRK3 | TDRKH | G4170 | CHD1L | MCM8 | FANCL | PIF1 | CHD7 | SOX8 | AMHR2 | HELQ | SETBP1 | SPIDR | NPM2 | LHB | G2099 | DNAH1 | PIWIL2 | POLK | CPEB3 | MRE11 | TSG101 | RAD50 | WDR33 | ERCC2 | BLM | MLH3 | NANOGNB | GREM1 | G836 | UBR2 | AFF2 | EIF4ENIF1 | LHCGR | SKP2 | WHAMM | FSD2 | ZP1 | CAMSAP2 | ZSWIM7 | NIN | HERC1 | NUPR1 | PREPL | TONSL | NPPC | G367 | KASH5 | NR2F2 | SAMHD1 | CLPP | MARF1 | NHEJ1 | PTPN22 | FANCF | NAP1L4 | GALT | SPATA22 | BRAT1 | HFM1 | SALL4 | FANCA | STAG1 | C3 | AMH | CPEB1 | GDF9 | RAD51C | PIWIL3 | APC2 | CLPB | USP9X | HAUS6 | NCAPG2 | SYCE1 | BMPR1A | TTLL1 | STAG3 | RUVBL2 | POF1B | DCP2 | G472 | G596 | NUP43 | FIGLA | BMPR1B | REC8 | ADAMTS1 | RPL5 | CPZ | PATL2 | ZFR2 | HK3 | FANCM | AP3B2 | NBN | C10orf90 | BMP15 | FMN2 | BMPR2 | DAZL | TARBP1 | NUP107 | NOBOX

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