Leiomyosarcoma

About the Disease
Leiomyosarcoma, also known as leiomyosarcomas, is related to uterus leiomyosarcoma and colon leiomyosarcoma. An important gene associated with Leiomyosarcoma is CHEK2 (Checkpoint Kinase 2), and among its related pathways/superpathways are Signal Transduction and ERK Signaling. The drugs Dacarbazine and Doxorubicin have been mentioned in the context of this disorder. Affiliated tissues include smooth muscle, uterus and lymph node, and related phenotypes are no effect and no effect

Common Targets
ATRX | G4609 | Ribonucleoside-diphosphate reductase | HDAC8 | PRKCA | DNA Topoisomerase II (nonspecified subtype) | FH | HDAC3 | FLT3 | BMI1 | RET | HDAC7 | CTLA4 | HDAC5 | G7157 | SDHB | SIRPA | RB1 | KIT | G472 | HDAC4 | SDHC | G9734 | DNA-Directed RNA Polymerase II | CYP19A1 | TOP2A | PARP2 | CD47 | TDO2 | SDHD | G1029 | Fibroblast Growth Factor Receptor (FGFR) (nonspecified subtype) | G5728 | E2F Transcription Factor (nonspecified subtype) | PRKCQ | G29126 | PDGFRB | CSF1R | ATR | SDHA | HDAC6 | HDAC2 | G3620 | ROR2 | G1956 | MED12 | CDK6 | CDK4 | G142 | TOP1 | MAP2K4 | G3569 | HDAC1 | G4233 | HDAC10 | KDR | FLT1 | FLT4

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