Disease

Neonatal Progeroid Syndrome

About the Disease
Wiedemann-Rautenstrauch Syndrome, also known as neonatal pseudo-hydrocephalic progeroid syndrome, is related to marfanoid-progeroid-lipodystrophy syndrome and progeroid syndrome, and has symptoms including action tremor and ataxia, truncal. An important gene associated with Wiedemann-Rautenstrauch Syndrome is POLR3A (RNA Polymerase III Subunit A). Affiliated tissues include skin, bone and skeletal muscle, and related phenotypes are frontal bossing and hypertelorism

Common Targets
FBN1 | YRDC | PYCR1 | RAF1 | SLC25A24 | LMNA | POLR3A | POLR3GL | POLD1

疾病靶点研报
Neonatal Progeroid Syndrome

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