Anencephaly

About the Disease
Anencephaly, also known as aprosencephaly, is related to neural tube defects, folate-sensitive and isolated anencephaly. An important gene associated with Anencephaly is CC2D2A (Coiled-Coil And C2 Domain Containing 2A), and among its related pathways/superpathways are Wnt / Hedgehog / Notch and RND3 GTPase cycle. The drugs Erenumab and Salmon calcitonin have been mentioned in the context of this disorder. Affiliated tissues include Neural Tube, brain and spinal cord, and related phenotypes are nervous system and growth/size/body region

Common Targets
SUFU | SHROOM3 | LILRB3 | TRIM36 | LIG3 | DYNC2I2 | MACF1 | TUBG1 | CEP85L | ASPM | LAMB1 | CDK5 | TP73 | ARX | CLASP1 | KIF2A | NDE1 | TUBA1A | NDEL1 | DCX | APC2 | SATB2 | PAFAH1B1 | TUBB3 | CRADD

Note: If you'd like to get a target analysis report for Anencephaly, or if you are interested to learn how our AI-powered BDE-Chem can design therapeutic molecules to interact with the target(s) above against the disease of Anencephaly at a cost 90% lower than traditional approaches, please feel free to contact us at BD@silexon.ai.

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