Disease

Mixed Connective Tissue Disease

About the Disease
Mixed Connective Tissue Disease, also known as sharp syndrome, is related to raynaud disease and systemic scleroderma. An important gene associated with Mixed Connective Tissue Disease is SNRNP70 (Small Nuclear Ribonucleoprotein U1 Subunit 70), and among its related pathways/superpathways are MIF Mediated Glucocorticoid Regulation and Processing of Capped Intron-Containing Pre-mRNA. The drugs Rituximab and Cyclophosphamide have been mentioned in the context of this disorder. Affiliated tissues include lung, kidney and skin, and related phenotypes are arthritis and gastroesophageal reflux

Common Targets
HLA-B | MRPL39 | HLA-DRB1 | MIR145 | MIR155HG | IL17F | IL10 | MIR146A | CARMN

疾病靶点研报
Mixed Connective Tissue Disease

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