Autism

About the Disease
Autism, also known as autistic disorder, is related to autism spectrum disorder and attention deficit-hyperactivity disorder. An important gene associated with Autism is SCN1A (Sodium Voltage-Gated Channel Alpha Subunit 1), and among its related pathways/superpathways are Neuroscience and Pathways affected in adenoid cystic carcinoma. The drugs Acetylcholine and Dopamine have been mentioned in the context of this disorder. Affiliated tissues include Umbilical Cord, brain and bone marrow, and related phenotypes are eeg abnormality and increased serum serotonin

Common Targets
AVPR1A | HTR3A | KDM5B | GPR139 | PCDHA8 | Serine/threonine-protein kinase (PAK) (nonspecified subtype) | THBS1 | SLC25A43 | COX2 | ASXL1 | AMPD1 | PCDHA7 | EXT1 | RNF135 | PCDHA6 | KCNC1 | UBE3B | GRM5 | ACE | SCFD2 | G4780 | PCDHA5 | Metabotropic glutamate (mGluR) receptor (nonspecified subtype) | MKNK2 | ABHD11 | LOC101928890 | CPT1C | PCDHA4 | HLA-DRB1 | KMT2C | EIF4A1 | CSDE1 | COX3 | TRNT | DAB1 | MTNR1A | DRD4 | PCDHA3 | DRD2 | LOC105373313 | Gamma-Aminobutyric acid type B receptor | Mitogen-Activated Protein Kinase (MAP Kinase)-Activated Protein Kinase (nonspecified subtype) | SIGMAR1 | MAOA | NCAM1 | MGLL | TRPM8 | G2475 | PCDHA9 | EIF4F translation-initiation complex | PCDHA2 | HTR1A | COMT | KCNQ3 | DENND2C | CHRM1 | PCDHA1 | SLC6A2 | CDKAL1 | BAIAP2 | ANKK1 | CLN3 | HTR2B | ASXL3 | CLTCL1 | ARID2 | TRPV1 | SPARCL1 | HCRTR1 | MKNK1 | CELF6 | GABA(A) receptor | PICALM | TRPV2 | MTRR | CACNA1C | EIF4E | Acetylcholine Receptors (Nicotinic) (nAChR) (nonspecified subtype) | CHRNA7 | ACHE | SLC6A9 | BICC1 | NLGN4X | AVPR2 | BCHE | Voltage-Gated Sodium Channel Complex | G4137 | Nicotinic alpha4beta2 receptor | INSR | GRM7 | MTNR1B | CALY | FOXP2 | GLO1 | GSK3B | ACADM | CPT2 | OXT | G4318 | FABP3 | EIF4G1 | RORA | G5243 | APBA2 | SSTR4 | EIF4G2 | LOC100507053 | Sodium channel (nonspecified subtype) | GRIN2A | RIMS3 | ADORA3 | VDR | SLC25A12 | MTHFR | GABRB3 | FABP5 | DLG4 | BCORL1 | GRM8 | DRD1 | EYS | BDNF-AS | SPRY3 | MMP2 | SLC6A4 | MYOM1 | NRXN1 | ENO2 | FABP7 | ATP13A4 | CNDP1 | PDE2A | KCNQ5 | TRIM33 | Dopamine receptor (nonspecified subtype) | NMDA receptor | HTR6 | SCN1A | GRM3 | S1PR5 | HTR2A | TRPA1 | SLC1A1 | SYNGAP1 | SNAP25 | EHMT2 | Histone deacetylase (nonspecified subtype) | CNTNAP2 | HTR1B | SLC5A1 | Cyclooxygenase (COX) (nonspecified subtype) | GABRA5 | 5-Hydroxytryptamine Receptor 2 (5-HT2) (nonspecified subtype) | CACNA1A | BCKDK | EIF4G3 | NCKAP5L | NT5E | GLP2R | SLC6A14 | KMT2D | SLC22A5 | STX1A | SLC8A2 | LOC105372283 | HTR2C | DRD3 | G2146 | GRM4 | CHD6 | HCN1 | MAOB | GPR55 | ABL1 | SLC9A9 | NF-kappaB (NFkB) | DNAAF4 | OXTR | ABAT | HNF1B | GRIN2B | FOS | RELN | Mitogen-activated protein kinase p38 (MAPK p38) (nonspecified subtype) | ZNF18 | HTR1D | PCDHA13 | KDM5A | COX1 | RORC | ADGRA2 | PCDHA12 | HTR7 | Glutamate Receptor Ionotropic AMPA Receptor | KAT2B | SCN2A | GSK3A | SERHL | MACROD2 | KCND2 | PCDHA11 | AHI1 | TRNP | BDNF | ALDH9A1 | PCDHA10

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