Disease

Hyperinsulinemic Hypoglycemia

About the Disease
Hyperinsulinemic Hypoglycemia, also known as nesidioblastosis, is related to hyperinsulinemic hypoglycemia, familial, 1 and hyperinsulinemic hypoglycemia, familial, 3. An important gene associated with Hyperinsulinemic Hypoglycemia is ABCC8 (ATP Binding Cassette Subfamily C Member 8), and among its related pathways/superpathways are Metabolism and Integration of energy metabolism. The drugs Somatostatin and Lanreotide have been mentioned in the context of this disorder. Affiliated tissues include pancreatic islet, pancreas and pituitary, and related phenotypes are Reduced mammosphere formation and homeostasis/metabolism

Common Targets
GH1 | GCK | HADHA | SSTR3 | G3630 | HADH | INSR | SLC16A1 | ABCC8 | CACNA1D | HNF1A | GLUD1 | SSTR5 | HNF4A | GLP1R | SSTR1 | GCGR | KCNJ11 | HLA-DRB1 | SSTR2 | PMM2

疾病靶点研报
Hyperinsulinemic Hypoglycemia

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