Common Variable Immunodeficiency

About the Disease
Common Variable Immunodeficiency, also known as cvid, is related to immunodeficiency, common variable, 1 and immunodeficiency, common variable, 2. An important gene associated with Common Variable Immunodeficiency is TNFRSF13B (TNF Receptor Superfamily Member 13B), and among its related pathways/superpathways are ERK Signaling and MIF Mediated Glucocorticoid Regulation. The drugs Rifaximin and Budesonide have been mentioned in the context of this disorder. Affiliated tissues include t cells, b cells and lung, and related phenotypes are chronic otitis media and brachycephaly

Common Targets
TCF3 | PIK3CD | IKZF1 | CD81 | TBX1 | HLA-A | LRBA | SYCP2 | NFKB2 | TNFSF13 | LOC101927840 | NOD2 | RAC2 | IRF2BP2 | TCF19 | LOC105369166 | IL7R | TNFSF12 | MSH5 | FCN3 | ZNF646 | POU5F1 | CTLA4 | G7015 | HLA-DPA1 | ADGRL2 | HLA-DQA2 | BACH2 | RAD50 | RTEL1 | NPIPB8 | BOLL | CTNNBL1 | FCGR2A | HLA-DPB1 | HLA-DQB1 | CLEC16A | FUS | HLA-C | TNFRSF13C | RNF31 | CD19 | G6774 | LOC101929772 | RAG1 | HLA-DRB1 | NFKB1 | FOXP3 | LOC105375005 | HCG20 | MSH5-SAPCD1 | TNFRSF13B | HLA-B | NLRP12 | ITGAM | LINC00221 | CR2 | PLCG2 | ICOS | HLA-DQA1 | FCN2

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