Woodhouse-Sakati Syndrome

About the Disease
Woodhouse-Sakati Syndrome, also known as diabetes-hypogonadism-deafness-intellectual disability syndrome, is related to dystonia and movement disease, and has symptoms including abnormality of extrapyramidal motor function An important gene associated with Woodhouse-Sakati Syndrome is DCAF17 (DDB1 And CUL4 Associated Factor 17), and among its related pathways/superpathways are Metabolism of water-soluble vitamins and cofactors and Autophagy. The drug Iron has been mentioned in the context of this disorder. Affiliated tissues include uterus, testes and thyroid, and related phenotypes are dysarthria and hypothyroidism

Common Targets
DCAF17

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