Cerebral Malaria

About the Disease
Malaria, also known as malaria, susceptibility to, is related to plasmodium falciparum malaria and plasmodium vivax malaria, and has symptoms including angina pectoris, chest pain and edema. An important gene associated with Malaria is SLC4A1 (Solute Carrier Family 4 Member 1 (Diego Blood Group)), and among its related pathways/superpathways are Innate Immune System and Response to elevated platelet cytosolic Ca2+. The drugs Lumefantrine and Artemether have been mentioned in the context of this disorder. Affiliated tissues include spleen, liver and t cells, and related phenotypes are nausea and vomiting and fever

Common Targets
STAT6 | IL17RA | IL4R | ABCA1 | G3569 | PROCR | Eukaryotic Translation Initiation Factor 4A (eIF-4A) | CR1 | HBB | IL4 | FCGR2A | RNASE3 | IFNAR1 | CXCL10 | G6PD | TLR7 | ABO | ATP2B4 | ART3 | CD40LG | LOC105372848

Note: If you'd like to get a target analysis report for Cerebral Malaria, or if you are interested to learn how our AI-powered BDE-Chem can design therapeutic molecules to interact with the target(s) above against the disease of Cerebral Malaria at a cost 90% lower than traditional approaches, please feel free to contact us at BD@silexon.ai.

Other Diseases

Hypokalemic Periodic Paralysis | Glycogen Storage Disease Type 1a | Agoraphobia | Aldosterone Synthase Deficiency | Osteosclerosis | Bone Giant Cell Tumor | Dyslexia | Pre-eclampsia | Osmotic Demyelination Syndrome | Primary Sclerosing Cholangitis | D-2-Hydroxyglutaric Aciduria | Fontaine Progeroid Syndrome | Ileitis | Basan Syndrome | Autosomal Recessive Spastic Paraplegia Type 75 | Corneal Neovascularization | Withdrawal Syndrome | Uveitis, Anterior | Sorsby Fundus Dystrophy | Chondrosarcoma | Hemimegalencephaly | Neural Tube Defect | Wieacker-Wolff Syndrome | Spondylocarpotarsal Synostosis Syndrome | Martsolf Syndrome | Alzheimer Disease, Late Onset | Retinitis Pigmentosa 3 | Anorectal Fistula | Papillon-Lefevre Syndrome | Hereditary Hemorrhagic Telangiectasia | Neonatal Progeroid Syndrome | Methemoglobinemia | Granular Corneal Dystrophy | Traboulsi Syndrome | Syndactyly | Hypertension, Renovascular | Hepatic Adenomatosis | Intestinal Tuberculosis | Generalized Epilepsy And Paroxysmal Dyskinesia | Hemochromatosis Type 1 | Prolymphocytic Leukemia | Methemoglobinemia Type IV | Hepatitis A | Neurofibroma | Herpes Simplex Dermatitis | Malonyl-CoA Decarboxylase Deficiency | Lymphopenia | Congenital Hemolytic Anemia | Coffin-Siris Syndrome | Splenomegaly | Glycogen Storage Disease Type 4 | Vitiligo | Esotropia | Hepatitis | Rosacea | Viral Meningitis | Metanephric Adenoma | Hepatopulmonary Syndrome | Multiple Mitochondrial Dysfunctions Syndrome Type 1 | Vascular Cognitive Impairment | Acrocallosal Syndrome | Cannabis Abuse | Sarcomatoid Carcinoma Of The Lung | Dowling-Degos Disease | Rhabdoid Tumor | Wolcott-Rallison Syndrome | Pseudoexfoliation Syndrome | Myocarditis | Ellis-Van Creveld Syndrome | Metaphyseal Chondrodysplasia, Schmid Type | Mucolipidosis Type III | Bursitis | Cholelithiasis | Epilepsy, Generalized | Cancer, Brain | Thyrotoxic Periodic Paralysis | Nutrition Disorders | Schizophrenia, Paranoid | Larsen Syndrome | Angioimmunoblastic T-cell Lymphoma | Spinocerebellar Ataxia Type 21 | X-linked Creatine Transporter Deficiency | Dysgerminoma | Combined Malonic And Methylmalonic Acidemia | Autonomic Nervous System Disorders | Benign Familial Infantile Seizures | Hypertension, Renal | Measles | Urethritis | Cerebrovascular Disorders | Focal Facial Dermal Dysplasia | Skin Papilloma | Bartter Syndrome | Retinal Dystrophy, Early-onset Severe | Prolidase Deficiency | Lewy Body Dementia | Leiomyosarcoma | Anorectal Malformations | Progressive Familial Intrahepatic Cholestasis Type 3 | Uremia | Spondyloperipheral Dysplasia | Hypoalbuminemia | Hodgkin Lymphoma | Frank-ter Haar Syndrome | DEND Syndrome | Rheumatic Heart Disease | Hyperostosis | Pleurisy | Parapsoriasis | Microcephalic Osteodysplastic Primordial Dwarfism, Type I | Encephalocele | Fundus Albipunctatus | Gastroenteritis, Eosinophilic | Peyronie's Disease | Ophthalmia, Sympathetic | Optic Neuropathy | Teratozoospermia | Frontotemporal Dementia With Amyotrophic Lateral Sclerosis | Congenital Central Hypoventilation Syndrome | Long QT Syndrome Type 3 | Patent Ductus Arteriosus | Hypertension, Essential | Glutaric Aciduria Type 2 | Creutzfeldt-Jakob Disease | Postaxial Polydactyly | 3-M Syndrome | AIDS | Glycogen Storage Disease Type 5 | Acrodermatitis | Leri Pleonosteosis | Hyperuricemia | Stickler Syndrome | Infantile Refsum Disease | Gingivitis | Transthyretin-related Amyloidosis | Polycythemia Vera | Oculopharyngeal Muscular Dystrophy | Ataxia-ocular Apraxia 2 | Cholecystitis | Erythrokeratodermia Variabilis | Hypereosinophilic Syndrome | Cryopyrin-associated Periodic Syndromes | McLeod Syndrome | Carcinoid Tumor | Ureteropelvic Junction Obstruction | Atrial Septal Defect | Acanthosis Nigricans | Carcinoma, Transitional Cell | Congenital Nephrotic Syndrome | Poirier-Bienvenu Neurodevelopmental Syndrome | Greenberg Dysplasia | Gyrate Atrophy Of The Choroid And Retina | PASLI Disease | Nephrotic Syndrome | Schizencephaly | Diarrhea | Carcinoma, Merkel Cell | Cri-du-chat Syndrome | Spinocerebellar Ataxia Type 40 | Spondylometaphyseal Dysplasia | Lattice Corneal Dystrophy | Kidney Stones | Macrophage Activation Syndrome | Proteus Syndrome | Neurofibromatosis | Astrocytoma, Anaplastic | Neuroectodermal Tumors, Primitive | Acrodysostosis | Proopiomelanocortin Deficiency | Polymyositis | Glycogen Storage Disease Type 0, Muscle | Adenoid Cystic Carcinoma | Gitelman Syndrome | Erythematotelangiectatic Rosacea | Osteonecrosis | C3 Glomerulonephritis | 3-hydroxyacyl-CoA Dehydrogenase Deficiency | Congenital Sodium Diarrhea | Pericarditis | Hemochromatosis Type 2 | Ocular Albinism Type 1 | Oculocutaneous Albinism Type 4 | Dysplastic Nevus | Blue Nevus | Addison Disease | Cerebrotendinous Xanthomatosis | Vogt-Koyanagi-Harada Syndrome | Metabolic Diseases | Autoimmune Autonomic Ganglionopathy | LRBA Deficiency | Keloid | Coenzyme Q10 Deficiency | Enlarged Vestibular Aqueduct | Diabetes Type 2 | Cyclic Vomiting Syndrome | Epidermolysis Bullosa | Chondrodysplasia Punctata | Protein S Deficiency | Neurofibrosarcoma | Fibronectin Glomerulopathy | Lactose Intolerance | Heart Septal Defects | Peroxisomal Disorder | Pseudohypoaldosteronism | Hereditary Pyropoikilocytosis | Neurofibromatosis Type 2 | Asthma | Hemochromatosis | Pseudohypoparathyroidism Type 1A | Priapism | Spitz Nevus | Focal Dermal Hypoplasia | B-cell Prolymphocytic Leukemia | Dupuytren Disease | Spinocerebellar Ataxia Type 16 | DNA Ligase IV Deficiency | Urea Cycle Disorder | Pituitary Disorders | L-2-Hydroxyglutaric Aciduria | Agnathia-Otocephaly Complex | Charcot-Marie-Tooth Disease Type 4E | Polyarteritis Nodosa | Zellweger Syndrome | Sarcosinemia | Craniofacial Dysostosis | Vulvovaginitis | Hypocalcemia | Anorexia Nervosa | Bladder Exstrophy | Cryptorchidism | Communication Disorders | Juvenile Myelomonocytic Leukemia | Filariasis | Chronic Idiopathic Myelofibrosis | Noonan Syndrome-like Disorder With Loose Anagen Hair | Arthritis | Glaucoma | Myasthenia | Gaze Palsy, Familial Horizontal, With Progressive Scoliosis, 2 | Congenital Lipoid Adrenal Hyperplasia | Tuberculous Meningitis | Hyperparathyroidism | Hemorrhoids | Takayasu's Arteritis | Dermatomyositis | Platyspondylic Lethal Skeletal Dysplasia, Torrance Type | Primary Carnitine Deficiency | Papilloma | Spina Bifida | Encephalitis | Hyperphenylalaninemia | Histiocytosis | Infertility | Chitayat Syndrome | Arts Syndrome | Adenylosuccinate Lyase Deficiency | Polycystic Kidney, Autosomal Recessive | Aspergillosis | Angioedema | Dermatitis Herpetiformis | Stevens-Johnson Syndrome | Carcinoma, Small Cell | Sengers Syndrome | Familial Pheochromocytoma-paraganglioma | Epilepsy Of Infancy With Migrating Focal Seizures | Nephrosclerosis | Multisystemic Smooth Muscle Dysfunction Syndrome | Ganglioglioma | Scleroderma, Diffuse | Cryptococcal Meningitis | Lymphomatoid Granulomatosis | Trichorhinophalangeal Syndrome | Spermatocele | Hepatoblastoma | Wolfram Syndrome | Paronychia | Mast Cell Leukemia | Congenital Dyserythropoietic Anemia Type 1 | Plasmacytoma | Gastric Atrophy | Proximal Symphalangism | Meningococcal Meningitis | Okihiro Syndrome | Micropenis | Roberts Syndrome | Citrullinemia | Lung Diseases | Nail-Patella Syndrome | Alpers Syndrome | Alveolar Capillary Dysplasia | Cholangiocarcinoma | Primary Cutaneous Amyloidosis | Mucolipidosis Type IV | Atelosteogenesis Type 1 | NGLY1 Deficiency | Graves Disease | Hereditary Folate Malabsorption | Autosomal Recessive Bestrophinopathy | Pulmonary Veno-occlusive Disease | Diffuse Intrinsic Pontine Glioma | Batten Disease | Medium-chain Acyl-CoA Dehydrogenase Deficiency | Atelosteogenesis Type 2 | Sleep Disorder | Pemphigus Vulgaris | Epicondylitis | Aromatic L-amino Acid Decarboxylase Deficiency | Osteogenesis Imperfecta Type V | Migraine | Warsaw Breakage Syndrome | Albinism | Hepatitis D | Antiphospholipid Syndrome | Nestor-Guillermo Progeria Syndrome | Pseudohypoparathyroidism Type 1C | Papillorenal Syndrome | Primary Progressive Nonfluent Aphasia | Common Cold | Agammaglobulinemia | Premature Ejaculation | Thin Basement Membrane Disease | Kaposi Sarcoma | Myotonia | Hypothalamic Obesity | Leber Congenital Amaurosis | Sotos Syndrome | Spitzoid Melanoma | Benign Recurrent Intrahepatic Cholestasis 1 | Hyperekplexia | Aicardi-Goutieres Syndrome | Pneumococcal Meningitis | Eosinophilia | Hyperparathyroidism, Secondary | Leukoplakia | Osteomalacia | Juvenile Xanthogranuloma | Stargardt Disease | Peeling Skin Syndrome, Acral Type | Lymphoma, B-cell | Smith-Kingsmore Syndrome | Tinea Versicolor | Congenital Hereditary Endothelial Dystrophy Type I | Bietti Crystalline Dystrophy | Ichthyosis | Dent Disease | Corticobasal Syndrome | Cervicitis | Renal Hypomagnesemia 3 | Usher Syndrome Type III | Malnutrition | Pupil Disorders | Cholera | Primary Pigmented Nodular Adrenocortical Disease | Miyoshi Myopathy | Renpenning Syndrome | Hyperhomocysteinemia | Postpoliomyelitis Syndrome | Multiple Congenital Anomalies-hypotonia-seizures Syndrome 2 | Cockayne Syndrome | Methylmalonic Acidemia | Episodic Ataxia | Megalencephaly | Bicuspid Aortic Valve | Chondrodysplasia Punctata 2, X-linked Dominant | Hemangioma | Long QT Syndrome Type 2 | Varices | Lentigo | Trichuriasis | Coma | Peripheral T-cell Lymphoma | Hypermethioninemia | Muckle-Wells Syndrome | Allergic Contact Dermatitis | Jalili Syndrome | Episodic Ataxia Type 1 | Epithelial-myoepithelial Carcinoma | Relapsing Polychondritis | Diabetes Insipidus, Nephrogenic | Chediak-Higashi Syndrome | Metatropic Dysplasia | Pemphigus Foliaceus | Lennox-Gastaut Syndrome | Esophageal Adenocarcinoma | Porphyria, Variegate | Hyperparathyroidism-jaw Tumor Syndrome | Basal Cell Nevus Syndrome | Mevalonate Kinase Deficiency | Cardiospondylocarpofacial Syndrome | Syncope | Lafora Disease | Metachondromatosis | Acute Kidney Injury | Sensory Ataxic Neuropathy, Dysarthria, And Ophthalmoparesis | ICF Syndrome | Stuve-Wiedemann Syndrome | Pineoblastoma | Familial Advanced Sleep Phase Syndrome | Ehlers-Danlos Syndrome With Progressive Kyphoscoliosis, Myopathy, And Hearing Loss | Cenani-Lenz Syndactyly Syndrome