Basal Ganglia Disease

About the Disease
Basal Ganglia Disease, also known as basal ganglia diseases, is related to thiamine metabolism dysfunction syndrome 2 and basal ganglia calcification. An important gene associated with Basal Ganglia Disease is DNAH7 (Dynein Axonemal Heavy Chain 7), and among its related pathways/superpathways are S1P3 pathway and S1P1 pathway. The drugs Cysteine and Soy Bean have been mentioned in the context of this disorder. Affiliated tissues include basal ganglia, cortex and brain, and related phenotypes are Synthetic lethal with MLN4924 (a NAE inhibitor) and Synthetic lethal with MLN4924 (a NAE inhibitor)

Common Targets
SLC20A2

Note: If you'd like to get a target analysis report for Basal Ganglia Disease, or if you are interested to learn how our AI-powered BDE-Chem can design therapeutic molecules to interact with the target(s) above against the disease of Basal Ganglia Disease at a cost 90% lower than traditional approaches, please feel free to contact us at BD@silexon.ai.

Other Diseases

Waardenburg Syndrome Type 1 | Bronchiectasis | Infertility | Plasma Cell Leukemia | Cushing Syndrome | Goldenhar Syndrome | Histoplasmosis | Sarcoma, Ewing | Gaze Palsy, Familial Horizontal, With Progressive Scoliosis, 2 | Myoclonus | Opisthorchiasis | Usher Syndrome Type II | Angioedema, Acquired | Lipid Metabolism Disorders | Thyroiditis | GNE Myopathy | Renal Failure | Spinocerebellar Ataxia Type 6 | Congenital Aniridia | Glanzmann Thrombasthenia | Plasmacytoma | Skin Papilloma | Dentinogenesis Imperfecta | Corneal Dystrophy And Perceptive Deafness | Erythromelalgia | Ectopia Lentis, Isolated, Autosomal Recessive | Benign Familial Pemphigus | Frontotemporal Dementia With Amyotrophic Lateral Sclerosis | Huntington's Disease | Sialidosis Type I | Methylmalonic Acidemia | Skin Carcinoma | Sclerosing Cholangitis | Cleidocranial Dysplasia | Myositis | Peutz-Jeghers Syndrome | Hypertrophic Osteoarthropathy, Primary, Autosomal Recessive 2 | Gastroschisis | Stroke, Ischemic | Cancer, Kidney | Cabezas Syndrome | Fukuyama Congenital Muscular Dystrophy | Ureteropelvic Junction Obstruction | Ovarian Hyperstimulation Syndrome | Turner's Syndrome | Fascioliasis | Cheilitis | Hereditary Hemorrhagic Telangiectasia Type 2 | Disseminated Superficial Actinic Porokeratosis | Hereditary Mixed Polyposis Syndrome | Encephalopathy, Glycine | Intestinal Hypomagnesemia 1 | Familial Hyperaldosteronism | Hemophilia | Intellectual Disability, Autosomal Dominant 5 | Eating Disorder | Keratosis, Seborrheic | Limb Girdle Muscular Dystrophy | Adenoma, Pleomorphic | Open-angle Glaucoma | Congenital Ichthyosiform Erythroderma | Carcinoma, Small Cell | Sarcomatoid Carcinoma Of The Lung | Diarrhea | Venous Insufficiency | Early Infantile Epileptic Encephalopathy 13 | Charcot-Marie-Tooth Disease Type 4 | Cluster Headache | Chronic Inflammatory Demyelinating Polyneuropathy | 3-hydroxy-3-methylglutaric Aciduria | Autosomal Recessive Spastic Paraplegia Type 35 | Papulopustular Rosacea | Sialoadenitis | Familial Hemiplegic Migraine | Hepatitis B, Chronic | Contact Dermatitis | Pneumonia, Mycoplasma | Charcot-Marie-Tooth Disease, Type 2 | X-linked Acrogigantism | Cholestasis, Intrahepatic | Papillorenal Syndrome | Hyperbilirubinemia, Neonatal | Christianson Syndrome | Autosomal Recessive Spastic Paraplegia Type 54 | Iron Overload | Diffuse Mesangial Sclerosis | Ellis-Van Creveld Syndrome | Cystitis, Interstitial | Non-Hodgkin Lymphoma | Carney Triad | Varices | Congenital Adrenal Hyperplasia 1 | Autosomal Recessive Bestrophinopathy | Essential Fructosuria | Atelosteogenesis Type 2 | Cavitary Optic Disc Anomalies | Nemaline Myopathy | Crigler-Najjar Syndrome | Dysmorphophobia | Hyperglycemia | Spinocerebellar Ataxia Type 8 | Chorea-acanthocytosis | Weill-Marchesani Syndrome | Coloboma | Kaposiform Hemangioendothelioma | Necrobiosis Lipoidica | Episodic Ataxia | Pompe Disease | Hypotrichosis, Congenital, With Juvenile Macular Dystrophy | Bietti Crystalline Dystrophy | Pituitary Stalk Interruption Syndrome | 3-methylglutaconic Aciduria | Craniolenticulosutural Dysplasia | Onchocerciasis | Myoclonic Atonic Epilepsy | Vitreoretinopathy, Proliferative | Platelet Disorders | Thrombophilia | Hairy Cell Leukemia | Bernard-Soulier Syndrome | Gardner Syndrome | Spermatocele | Infantile Liver Failure Syndrome 1 | Mitochondrial Disease | Spinocerebellar Ataxia Type 5 | Keratocystic Odontogenic Tumor | Pancytopenia | Otitis Externa | Antithrombin III Deficiency | Frank-ter Haar Syndrome | Wolfram Syndrome 2 | Multiple Mitochondrial Dysfunctions Syndrome Type 1 | Glomerulonephritis, Membranous | Hypertension, Renal | Hyperlipidemia | Osteoporosis-pseudoglioma Syndrome | Adenoma, Pituitary | Myhre Syndrome | Glycogen Storage Disease Type 1a | Frontotemporal Dementia | Blepharitis | Liver Failure, Acute Infantile | Tendinopathy | Esotropia | Macrophage Activation Syndrome | Retinopathy, Diabetic | Pneumonia, Bacterial | Urethritis | Spinal Muscular Atrophy Type 3 | Arthrogryposis | Fibromyalgia | Thrombasthenia | Sarcoma | Ghosal Syndrome | Strabismus | Anxiety Disorders | Pulmonary Capillary Hemangiomatosis | Retinal Detachment | Kearns-Sayre Syndrome | Dyslipidemia | Acute Kidney Injury | Microvillus Inclusion Disease | Coma | Lymphedema | Hydronephrosis | Pycnodysostosis | Diabetes Insipidus, Neurogenic | Apraxia | Hyperkeratosis | Miyoshi Myopathy | Alexander Disease | Hodgkin Lymphoma | Angioedema | Chronic Granulomatous Disease, X-linked | Eiken Syndrome | Nutrition Disorders | Nestor-Guillermo Progeria Syndrome | Lipoma | Osteonecrosis | Autism Spectrum Disorders | Bethlem Myopathy | Hepatitis E | Lattice Corneal Dystrophy Type 1 | Myelomeningocele | Autosomal Recessive Spastic Paraplegia Type 75 | Mesial Temporal Lobe Epilepsy With Hippocampal Sclerosis | Intestinal Tuberculosis | Bartsocas-Papas Syndrome | Glycogen Storage Disease Type 1b | Hyperbilirubinemia | Rhabdomyosarcoma, Embryonal | Paraganglioma, Carotid Body | Hydrops Fetalis | Transthyretin-related Amyloidosis | Pseudo-pseudohypoparathyroidism | Colitis | Choreoathetosis, Hypothyroidism, And Neonatal Respiratory Distress | Spastic Paraplegia Type 7 | Carcinoid Syndrome | Ligneous Conjunctivitis | Gyrate Atrophy Of The Choroid And Retina | Splenomegaly | Optic Nerve Hypoplasia, Bilateral | Angina Pectoris | Proteus Syndrome | Diabetic Neuropathy | Polycystic Liver | Cirrhosis | Citrullinemia | Nephronophthisis | Stroke | Pregnancy, Ectopic | Hydrocephalus | Chronic Granulomatous Disease | Light Chain Amyloidosis | Facioscapulohumeral Muscular Dystrophy Type 2 | Colorectal Adenoma | Glycogen Storage Disease | Long QT Syndrome Type 2 | Antenatal Bartter Syndrome Type 1 | Pituitary Dwarfism | Basal Ganglia Disease | Neurodevelopmental Disorder With Central Hypotonia And Dysmorphic Facies | Focal Facial Dermal Dysplasia | Thyroid Dyshormonogenesis | Intermittent Claudication | Common Cold | Cysticercosis | Methemoglobinemia Type IV | Thalassemia, Beta | Glioblastoma | Progressive External Ophthalmoplegia | Crimean-Congo Hemorrhagic Fever | Toxoplasmosis | Histiocytic Sarcoma | Hypogammaglobulinemia | Whipple's Disease | Spondylo-ocular Syndrome | Hereditary Folate Malabsorption | Genitopatellar Syndrome | Fetal Akinesia Deformation Sequence | Craniometaphyseal Dysplasia | Fetal And Neonatal Alloimmune Thrombocytopenia | Autism | Bleeding Disorder Due To CalDAG-GEFI Deficiency | Lattice Corneal Dystrophy | C3 Glomerulopathy | Veno-occlusive Disease | Saethre-Chotzen Syndrome | Infantile Refsum Disease | Osteogenesis Imperfecta Type VI | McCune-Albright Syndrome | Tonsillitis | Fucosidosis | Nicotine Dependence | Cantu Syndrome | Hepatic Adenomatosis | Thymoma, Malignant | Kindler Syndrome | Osteochondrosis | Liver Failure | Trichomegaly | Arrhythmogenic Right Ventricular Cardiomyopathy | Cole-Carpenter Syndrome | Eosinophilia | Waardenburg Syndrome Type 2E | Alcoholism | Angiomyolipoma | Diabetes Type 1 | 3C Syndrome | Pouchitis | Sturge-Weber Syndrome | Encephalopathy, Ethylmalonic | Sarcoidosis | Basal Ganglia Disease, Biotin-responsive | Nasodigitoacoustic Syndrome | Anuria | Bacterial Meningitis | Apert Syndrome | Hypertelorism | Acrodermatitis Enteropathica | Carcinoid Tumor | Placenta Previa | Infectious Diarrhea | T-cell Lymphoma, Subcutaneous Panniculitis-like | CDKL5 Deficiency Disorder | Congestive Heart Failure | Syndactyly | Ocular Hypertension | Smith-Kingsmore Syndrome | Follicular Dendritic Cell Sarcoma | Non-Langerhans Cell Histiocytosis | Cold-induced Sweating Syndrome | Autoimmune Polyendocrine Syndrome | Idiopathic Pulmonary Fibrosis | Endometritis | Malignant Fibrous Histiocytoma | Gingivitis | Congenital Diaphragmatic Hernia | Measles | Loeys-Dietz Syndrome Type 4 | Hypoplastic Left Heart Syndrome | Lymphoma, Primary Cutaneous Anaplastic Large Cell | Fatty Aldehyde Dehydrogenase Deficiency | FG Syndrome | Fibrodysplasia Ossificans Progressiva | Gangliosidosis | Blepharo-cheilo-odontic Syndrome | Metanephric Adenoma | Ocular Surface Squamous Neoplasia | Homocystinuria | Hereditary Neuropathy With Liability To Pressure Palsies | Urolithiasis | Ileitis | Hyperthermia, Malignant | Scleroderma | Blepharospasm | Spondylocostal Dysostosis | Trichuriasis | Gaucher Disease | Microtia | Marinesco-Sjogren Syndrome | Corticobasal Syndrome | Waardenburg Syndrome Type 2 | Specific Granule Deficiency | Renal Hypouricemia | Multiple Epiphyseal Dysplasia | Agranulocytosis | Dyskeratosis Congenita | Urofacial Syndrome | Infantile Neuroaxonal Dystrophy | Lipid Storage Myopathy | Central Core Disease | Micro Syndrome | Graft-versus-host Disease | Hypermetropia | Long QT Syndrome Type 3 | Familial Exudative Vitreoretinopathy | Hypoproteinemia, Hypercatabolic | Rolandic Epilepsy | Retinitis Pigmentosa | Blau Syndrome | Chronic Myeloid Leukemia | N-acetylglutamate Synthase Deficiency | Knobloch Syndrome | Spinocerebellar Ataxia Type 15 | Arthritis, Psoriatic | PHARC Syndrome | Parkinson's Disease | Holoprosencephaly | Angiosarcoma | Kleine-Levin Syndrome | Apparent Mineralocorticoid Excess Syndrome | Primary Lateral Sclerosis | Ocular Albinism Type 1 | Adams-Oliver Syndrome | Mucolipidosis | Metabolic Syndrome | Inborn Errors Of Metabolism | Kashin-Beck Disease | Coffin-Siris Syndrome | Asthma | Cryopyrin-associated Periodic Syndromes | Thalassemia | Idiopathic Multicentric Castleman Disease | Diabetes Insipidus | Hepatic Steatosis | Macular Corneal Dystrophy | Isovaleric Acidemia | Cystitis | Hyperphenylalaninemia | Congenital Bile Acid Synthesis Defect | Pure Red Cell Aplasia | GLUT1 Deficiency Syndrome | Leber Congenital Amaurosis | Acrodermatitis | Parkinsonism | Angioimmunoblastic T-cell Lymphoma | Perivascular Epithelioid Cell Tumor | 5-oxoprolinase Deficiency | Adenoma, Villous | Usher Syndrome Type I | Coronary Artery Disease | Trigonocephaly | Systemic Lupus Erythematosus | Achondrogenesis | Fontaine Progeroid Syndrome | Retinoblastoma | Sorsby Fundus Dystrophy | Van Der Knaap Disease | Adrenal Insufficiency | Situs Inversus | Hereditary Pyropoikilocytosis | Oculocutaneous Albinism Type 4 | Pemphigoid | Mood Disorder | Charcot-Marie-Tooth Disease, Type 2A | Intestinal Obstruction | 6-pyruvoyl-tetrahydropterin Synthase Deficiency | Spinocerebellar Ataxia Type 10