Necrobiosis Lipoidica

About the Disease
Necrobiosis Lipoidica, also known as oppenheim-urbach disease, is related to renal glucosuria and tuberculoid leprosy. An important gene associated with Necrobiosis Lipoidica is CD163 (CD163 Molecule), and among its related pathways/superpathways are Hematopoietic Stem Cells and Lineage-specific Markers and Roles of ceramides in the development of insulin resistance. Affiliated tissues include skin, neutrophil and thyroid, and related phenotypes are inflammatory abnormality of the skin and annular cutaneous lesion

Common Targets
Phosphodiesterase (nonspecified subtype)

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