Ventricular Septal Defect
Ventricular Septal Defect
About the Disease
Ventricular Septal Defect, also known as ventricular septal defects, is related to tetralogy of fallot and heart septal defect. An important gene associated with Ventricular Septal Defect is FOXP4 (Forkhead Box P4), and among its related pathways/superpathways are Human Embryonic Stem Cell Pluripotency and Mesenchymal Stem Cells and Lineage-specific Markers. The drugs Salbutamol and Adrenergic Agonists have been mentioned in the context of this disorder. Affiliated tissues include heart, lung and smooth muscle, and related phenotypes are Increased shRNA abundance (Z-score > 2) and Increased shRNA abundance (Z-score > 2)
Common Targets
POLR1HASP | GATA4 | NFATC1 | GDF1 | TNFSF11 | FGFR1 | MTRR | PLAGL1 | TCF21 | KDR | NKX2-5 | HAS2 | DSP | HOXA1 | G7422 | JUP | NRP1 | GATA5 | GPC5 | NR2F2 | FIGN | STX18-AS1 | SMAD3 | NKX2-6 | MTR | ABL1 | BCL6 | TWIST1 | HEY2 | SCO2 | FMN1 | BAG3 | POLR1H | HOMEZ | SCN10A

Note: If you'd like to get a target analysis report for Ventricular Septal Defect, or if you are interested to learn how our AI-powered BDE-Chem can design therapeutic molecules to interact with the target(s) above against the disease of Ventricular Septal Defect at a cost 90% lower than traditional approaches, please feel free to contact us at BD@silexon.tech.
Other Diseases
Cold Agglutinin Disease | Beckwith-Wiedemann Syndrome | Meesmann Corneal Dystrophy | Varices | Leukoencephalopathy, Progressive Multifocal | Endometriosis | LEOPARD Syndrome | Maternally Inherited Diabetes And Deafness | KBG Syndrome | Colon Adenoma | Vitelliform Macular Dystrophy | Eosinophilic Asthma | Osteomalacia | Pontocerebellar Hypoplasia Type 7 | Arts Syndrome | Pupil Disorders | Chondrodysplasia Punctata | Keratocystic Odontogenic Tumor | Angiodysplasia | Vertigo | Prolactinoma | Varicocele | Depression | Myositis, Focal | Cyst | Cardiac Arrest | Neural Tube Defect | Familial Mediterranean Fever | Leukocyte Adhesion Deficiency | Usher Syndrome Type IIC | Cancer, Lung | Alexander Disease | Gardner Syndrome | Hypercalciuria | X-linked Charcot-Marie-Tooth Disease | Retinal Dystrophy | Encephalocele | Marinesco-Sjogren Syndrome | Combined Deficiency Of Factor V And Factor VIII | Macrophage Activation Syndrome | Cold-induced Sweating Syndrome | Priapism | Panniculitis | Long QT Syndrome Type 2 | Intestinal Tuberculosis | Primary Carnitine Deficiency | Fetal Alcohol Syndrome | Glycogen Storage Disease Type 0 | Fuchs Dystrophy | Arthrogryposis | Barakat Syndrome | Fibrosis | Otopalatodigital Syndrome Type 2 | Hepatitis, Chronic | Aneurysm, Thoracic Aortic | Erythematotelangiectatic Rosacea | Pelizaeus-Merzbacher Disease | Progressive Myoclonic Epilepsy | Influenza | Hepatorenal Syndrome | Episodic Ataxia | Personality Disorders | Bacterial Meningitis | Central Core Disease | Bloom Syndrome | Iron Overload | Progressive Osseous Heteroplasia | Pituitary Stalk Interruption Syndrome | Cluster Headache | Neuroectodermal Tumors, Primitive | Calcium Pyrophosphate Deposition Disease | Hereditary Xerocytosis | Autosomal Recessive Spastic Paraplegia Type 75 | Mitochondrial DNA Depletion Syndrome 13 | 3C Syndrome | Hypophosphatemic Rickets, Autosomal Recessive, 1 | Hypertriglyceridemia | Gilbert Syndrome | Nail Disorder, Nonsyndromic Congenital | Preaxial Polydactyly | Purpura | Joubert Syndrome | T-cell Chronic Lymphocytic Leukemia | Meningitis | Ureteropelvic Junction Obstruction | Wolman Disease | Granular Corneal Dystrophy Type 1 | Myoclonus | Hyperuricemic Nephropathy, Familial Juvenile | Micropenis | Charcot-Marie-Tooth Disease, Type 1A | Aldosteronism | Neurodevelopmental Disorders | Microvillus Inclusion Disease | Pycnodysostosis | Antiphospholipid Syndrome | Omenn Syndrome | Cat Eye Syndrome | Cancer, Kidney | Motion Sickness | Vitamin B12 Deficiency | Contact Dermatitis | Sandhoff Disease | Giant Cell Glioblastoma | Ovarian Sex Cord-stromal Tumor | Epidermolysis Bullosa Dystrophica | Hypertelorism | Cardiomyopathy, Restrictive | Esthesioneuroblastoma | Parvovirus B19 Infection | Castleman Disease | Non-proliferative Diabetic Retinopathy | Infantile Neuroaxonal Dystrophy | Vertebrobasilar Insufficiency | Inflammatory Joint Disease | Oligoasthenoteratozoospermia | Dermatitis | Lymphoma, B-cell | Addison Disease | Agnathia-Otocephaly Complex | Keratitis | Asperger Syndrome | Fanconi Syndrome | Spinocerebellar Ataxia Type 16 | Optic Neuropathy, Anterior Ischemic | Costello Syndrome | Cryptorchidism | Stiff-man Syndrome | Burn-McKeown Syndrome | Myhre Syndrome | Niemann-Pick Disease, Type A | Pyruvate Decarboxylase Deficiency | Diabetes Mellitus, Transient Neonatal | Hemolytic Uremic Syndrome, Atypical | Cannabis Abuse | Chiari Malformation Type I | Brachydactyly | Chronic Myelomonocytic Leukemia | Dengue Hemorrhagic Fever | Neurogenic Bladder | Methylmalonic Acidemia | Acute Lymphocytic Leukemia | Martsolf Syndrome | Lysosomal Acid Lipase Deficiency | Exocrine Pancreatic Insufficiency | Heart Septal Defects | Spinal Muscular Atrophy Type 2 | Endophthalmitis | Multiple Sulfatase Deficiency | Neurodevelopmental Disorder With Central Hypotonia And Dysmorphic Facies | Ichthyosis Hystrix, Curth-Macklin Type | Carotid Artery Disease | Progressive Encephalopathy-optic Atrophy Syndrome | Waardenburg Syndrome Type 4A | 3-methylcrotonyl-CoA Carboxylase Deficiency | Glaucomatocyclitic Crisis | Hoyeraal-Hreidarsson Syndrome | Osteosarcoma | Prolidase Deficiency | Pre-eclampsia | Chromosome 16p11.2 Deletion Syndrome | Deafness, Dystonia, And Cerebral Hypomyelination | Impetigo | Cerebrotendinous Xanthomatosis | Spinocerebellar Ataxia Type 28 | Megaloblastic Anemia | Postpoliomyelitis Syndrome | Stomatitis | Aplasia Cutis Congenita | Myopathy | Mitochondrial Myopathy | Diabetes Insipidus | Spinocerebellar Ataxia Type 31 | Vitiligo | Cholecystitis | Hypoproteinemia, Hypercatabolic | Primary Erythromelalgia | Acral Lentiginous Melanoma | Osteogenesis Imperfecta Type VI | Dental Caries | Primary Ovarian Insufficiency | Chromosome 9q34.3 Deletion Syndrome | Measles | McCune-Albright Syndrome | Mastitis | Syphilis | Poretti-Boltshauser Syndrome | Peritonitis | Dystonia Musculorum Deformans | Chronic Myeloid Leukemia | Cousin Syndrome | Pelvic Inflammatory Disease | Common Variable Immunodeficiency | Non-bullous Congenital Ichthyosiform Erythroderma | Sleep Apnea | Smith-Magenis Syndrome | Hypercalcemia | Amyotrophic Lateral Sclerosis-parkinsonism-dementia Complex | Spinocerebellar Ataxia Type 27 | Renal-hepatic-pancreatic Dysplasia | Bainbridge-Ropers Syndrome | Echinococcosis | Hemimegalencephaly | Paroxysmal Kinesigenic Dyskinesia | Guillain-Barre Syndrome | Strabismus | Benign Familial Neonatal Convulsions | PHARC Syndrome | Discoid Lupus Erythematosus | Pierson Syndrome | Thromboembolism | Optic Atrophy 2 | Congenital Dyserythropoietic Anemia Type 4 | Encephalopathy, Ethylmalonic | Hypertensive Retinopathy | Trimethylaminuria | Dermatomyositis | Dystrophy, Cone-rod | Choriocarcinoma | Vitamin K Deficiency | Renal Failure | Language Disorders | Hypertension, Essential | Hypertrophic Osteoarthropathy, Primary, Autosomal Recessive 1 | Anorexia Nervosa | Familial Thoracic Aortic Aneurysm | Primary Progressive Aphasia | Tyrosinemia Type 1 | Porphyria, Variegate | Adenoma, Pituitary | Fabry's Disease | Hereditary Sensory And Autonomic Neuropathy | Nicotine Addiction | Choreoathetosis, Hypothyroidism, And Neonatal Respiratory Distress | Vasculitis | Extramammary Paget's Disease | Generalized Epilepsy With Febrile Seizures Plus | Pseudoachondroplasia | Adenomatoid Tumor | Focal Facial Dermal Dysplasia | Combined Malonic And Methylmalonic Acidemia | Otosclerosis | Proteus Syndrome | Ganglioglioma | Synpolydactyly | Poikiloderma With Neutropenia | Cysticercosis | Epicondylitis | Inborn Errors Of Metabolism | Spondylocarpotarsal Synostosis Syndrome | Pontocerebellar Hypoplasia Type 2 | Sick Sinus Syndrome 1 | Pulmonary Vein Stenosis | Chronic Periodontitis | Ghosal Syndrome | Patent Ductus Arteriosus | Neonatal Progeroid Syndrome | Thrombasthenia | Fukuyama Congenital Muscular Dystrophy | Postpartum Depression | Neurocutaneous Syndromes | Pemphigus Foliaceus | Pericarditis | Leukoplakia | Hypotrichosis, Congenital, With Juvenile Macular Dystrophy | Lupus Erythematosus | Hidradenitis | Zimmermann-Laband Syndrome | Osteosclerosis | Klinefelter Syndrome | Larsen Syndrome | Tangier Disease | Coffin-Siris Syndrome | Nephronophthisis | DICER1 Syndrome | Congenital Aniridia | Pyelonephritis | Long QT Syndrome Type 1 | Leri-Weill Dyschondrosteosis | Localized Scleroderma | Wolfram Syndrome 2 | Uterine Leiomyoma | Blood Protein Disorders | Epidermolytic Hyperkeratosis | Cancer, Breast | Idiopathic Multicentric Castleman Disease | Tietze Syndrome | Learning Disability | Cataplexy | Alopecia | Heroin Dependence | Hodgkin Lymphoma | Lennox-Gastaut Syndrome | Dentinogenesis Imperfecta | HIBCH Deficiency | Dysferlinopathy | Facioscapulohumeral Muscular Dystrophy | Hyperlipidemia, Familial Combined | Retinal Telangiectasia | Absence Epilepsy | Pigment Dispersion Syndrome | Coenzyme Q10 Deficiency | Retinal Vasculitis | Cutis Laxa | Atrial Septal Defect | Rubeosis Iridis | Renal Hypouricemia | Lymphopenia | Pulmonary Stenosis | Senior-Loken Syndrome | Glycogen Storage Disease Type 1b | Carcinoma In Situ | Schwannomatosis | Niemann-Pick Disease | Papilledema | Familial Exudative Vitreoretinopathy | Carbamoyl Phosphate Synthetase I Deficiency | Smoldering Myeloma | Dyslexia | Spinocerebellar Ataxia Type 10 | Oculocutaneous Albinism Type 4 | Carey-Fineman-Ziter Syndrome | CHARGE Syndrome | Epilepsy Of Infancy With Migrating Focal Seizures | Fibronectin Glomerulopathy | Chediak-Higashi Syndrome | Dysthymia | Alcoholism | Pneumonia, Viral | Bartsocas-Papas Syndrome | Progressive Familial Intrahepatic Cholestasis | Synovitis | Nemaline Myopathy | Aplastic Anemia | Borderline Personality Disorder | Brugada Syndrome 1 | Craniosynostosis | Non-epidermolytic Palmoplantar Keratoderma | Sarcomatoid Carcinoma Of The Lung | Autoimmune Interstitial Lung, Joint, And Kidney Disease | Stargardt Disease | Genee-Wiedemann Syndrome | Ileitis | Oligoastrocytoma | Necrotizing Autoimmune Myopathy | Peeling Skin Syndrome Type B | Lentigo | Essential Fructosuria | Spinocerebellar Ataxia Type 38 | Johanson-Blizzard Syndrome | Achromatopsia | Sclerosing Cholangitis | Waldenstrom Macroglobulinemia | Osteomyelitis | Palsy, Cerebral | Hypokalemia | Cutaneous Angiosarcoma | Infantile Liver Failure Syndrome 1 | Epidermolysis Bullosa Simplex | Hepatoblastoma | Mucolipidosis Type II | Hernia, Inguinal | Meningeal Melanocytoma | NDH Syndrome | Mucormycosis | FG Syndrome | Postaxial Polydactyly | Pterygium | Spinal Muscular Atrophy | Cushing Syndrome | Congenital Dysfibrinogenemia | Atopy | Fucosidosis | Pilomatrix Carcinoma | Gingivitis | Peripheral T-cell Lymphoma | Cantu Syndrome | Large Granular Lymphocytic Leukemia | Best Macular Dystrophy | Hyperphenylalaninemia | Malnutrition | Fundus Albipunctatus | Lymphoma, Primary Cutaneous Anaplastic Large Cell | Multiple Hamartoma Syndrome | Hyperparathyroidism, Primary | Obsessive-compulsive Disorder | Leukemia | Mitochondrial Encephalomyopathy | Autoimmune Autonomic Ganglionopathy | Aromatic L-amino Acid Decarboxylase Deficiency | Congenital Bile Acid Synthesis Defect | Melanoma | Neurofibromatosis | Palmoplantar Keratoderma | Sezary Syndrome | Lymphomatoid Granulomatosis | Pseudohermaphroditism | Craniolenticulosutural Dysplasia | Hamartoma | Keratosis, Actinic