Schnitzler Syndrome

About the Disease
Schnitzler Syndrome, also known as chronic urticaria with macroglobulinemia, is related to urticaria and exanthem, and has symptoms including rash An important gene associated with Schnitzler Syndrome is IL1R1 (Interleukin 1 Receptor Type 1), and among its related pathways/superpathways are Innate Immune System and Disease. The drugs Rilonacept and Dapansutrile have been mentioned in the context of this disorder. Affiliated tissues include bone, spleen and skin, and related phenotypes are splenomegaly and hepatomegaly

Common Targets
Interleukin-1 (nonspecified subtype) | IRAK4 | IL1B | NLRP3 Inflammasome | CRBN | IL6R | G114548

Note: If you'd like to get a target analysis report for Schnitzler Syndrome, or if you are interested to learn how our AI-powered BDE-Chem can design therapeutic molecules to interact with the target(s) above against the disease of Schnitzler Syndrome at a cost 90% lower than traditional approaches, please feel free to contact us at BD@silexon.ai.

Other Diseases

Spondylolisthesis | Usher Syndrome Type I | Oculocutaneous Albinism Type 4 | Spinocerebellar Ataxia Type 7 | Spinocerebellar Ataxia Type 10 | Hartsfield Syndrome | Ocular Albinism Type 1 | Pulmonary Vein Stenosis | Pycnodysostosis | Autosomal Recessive Congenital Ichthyosis | Ollier Disease | Cerebrotendinous Xanthomatosis | Constipation | Neurofibrosarcoma | Chronic Granulomatous Disease | Acrodermatitis Enteropathica | Basal Cell Nevus Syndrome | Congenital Heart Defects | Spinocerebellar Ataxia Type 27 | Rhabdomyosarcoma | Pelizaeus-Merzbacher Disease | Hyperparathyroidism | Persistent Truncus Arteriosus | Porphyria | Lafora Disease | Prune Belly Syndrome | B-cell Prolymphocytic Leukemia | Leigh Syndrome | Osteoporosis | Pilomatrix Carcinoma | Endometriosis | Hyperuricemia | Familial Hypertrophic Cardiomyopathy | Varicocele | Glaucomatocyclitic Crisis | Congenital Nephrotic Syndrome | Pseudoexfoliation Syndrome | Megaloblastic Anemia | Leishmaniasis, Cutaneous | Campomelic Dysplasia | Epidermolysis Bullosa | Blue Nevus | Sotos Syndrome | Saul-Wilson Syndrome | Cannabis Abuse | Steel Syndrome | Cushing Syndrome | PASLI Disease | Porphyria, Variegate | Alpha-1 Antitrypsin Deficiency | Still Disease | Diabetes Gestational | Osteopathia Striata With Cranial Sclerosis | Dengue Hemorrhagic Fever | Multiple Sclerosis | Gigantism | Schwannoma | Diabetes Insipidus, Nephrogenic | Cockayne Syndrome | Hypertriglyceridemia | Richter's Syndrome | Lamellar Ichthyosis | Transcobalamin Deficiency | Hypertrophic Osteoarthropathy, Primary, Autosomal Recessive 1 | Lung Diseases | Thyroiditis | Leri Pleonosteosis | Hypertension, Essential | Granular Corneal Dystrophy | Sorsby Fundus Dystrophy | Encephalitis | Papilloma | Hypertension, Pulmonary | Auriculocondylar Syndrome | CREST Syndrome | Leukoplakia, Oral | Neurodevelopmental Disorders | Hypermetropia | Zimmermann-Laband Syndrome | Pyoderma Gangrenosum | Fucosidosis | Adenoma, Villous | Primary Aldosteronism | Sialoadenitis | Infertility | Basal Ganglia Disease, Biotin-responsive | Spondyloepimetaphyseal Dysplasia With Joint Laxity, Type 3 | Stroke | Acute Lymphocytic Leukemia | Wagner Disease | IgA Nephropathy | Multiple Mitochondrial Dysfunctions Syndrome Type 1 | Amenorrhea | Methylmalonic Aciduria And Homocystinuria, CblC Type | Centronuclear Myopathy | Antisynthetase Syndrome | DEND Syndrome | Generalized Epilepsy With Febrile Seizures Plus | Intestinal Pseudo-obstruction | Renal Dysplasia | Fibromyalgia | Atrial Septal Defect | Gliosarcoma | Cholesteryl Ester Storage Disease | Hemochromatosis Type 1 | Craniometaphyseal Dysplasia | Hereditary Coproporphyria | Retinal Telangiectasia | Alagille Syndrome | Glanzmann Thrombasthenia | Alzheimer Disease, Late Onset | Hemangioma | Duane Retraction Syndrome | Carney-Stratakis Syndrome | Disseminated Superficial Actinic Porokeratosis | Ligneous Conjunctivitis | Cholestasis, Intrahepatic | Scleroderma | Hypertrophy | Canavan Disease | Rhizomelic Chondrodysplasia Punctata | Amelogenesis Imperfecta | Dermatomyositis | Congenital Afibrinogenemia | Carpal Tunnel Syndrome | Diabetes Insipidus, Neurogenic | Chorea | Nicotine Dependence | Glycogen Storage Disease Type 0, Muscle | Feingold Syndrome | Macular Corneal Dystrophy Type 1 | Personality Disorders | Schamberg Disease | Multiple Sclerosis, Secondary Progressive | Neuroectodermal Tumors, Primitive | Myotonia | Lattice Corneal Dystrophy | 3-hydroxyacyl-CoA Dehydrogenase Deficiency | Intermittent Explosive Disorder | Periventricular Leukomalacia | Sickle Cell Anemia | Glioblastoma Multiforme | Epidermolysis Bullosa Simplex, Generalized | Martsolf Syndrome | Conduct Disorder | Holoprosencephaly | Amyloidosis | Necrobiosis Lipoidica | Thrombocythemia, Essential | Dystonia Musculorum Deformans | Papulopustular Rosacea | Mitochondrial Cytopathy | Platelet Disorders | Cryptosporidiosis | Rosacea | Atelosteogenesis Type 1 | Argininosuccinic Aciduria | Basal Ganglia Disease | Goiter | Alpers Syndrome | Hypereosinophilic Syndrome | Lymphedema-distichiasis Syndrome | Pendred Syndrome | Hypotrichosis Simplex | Atopic Dermatitis | Glaucoma, Congenital | Relapsing Polychondritis | Pathological Gambling | Motion Sickness | Scabies | Fatty Aldehyde Dehydrogenase Deficiency | Galloway-Mowat Syndrome | Dentinogenesis Imperfecta | Beare-Stevenson Syndrome | Carbamoyl Phosphate Synthetase I Deficiency | Glycogen Storage Disease | Thromboembolism | Cone Dystrophy | Vascular Cognitive Impairment | Chromosome 5q Deletion Syndrome | Chronic Leukemia | Erysipelas | Dengue Shock Syndrome | Asphyxia Neonatorum | Aldosterone Deficiency | Pompe Disease | Acute Motor Axonal Neuropathy | Congenital Generalized Lipodystrophy | Cousin Syndrome | Congenital Disorders Of Glycosylation | Smoldering Myeloma | Alexander Disease | McCune-Albright Syndrome | Usher Syndrome Type IIC | Lysosomal Acid Lipase Deficiency | Hypertelorism | Dysfibrinogenemia | Zollinger-Ellison Syndrome | Renal Hypouricemia | Greig Cephalopolysyndactyly Syndrome | Agranulocytosis | Lipodystrophy | Onchocerciasis | Hemolytic Anemia | Renal Oncocytoma | Hypertension, Renal | Hypotrichosis, Congenital, With Juvenile Macular Dystrophy | Ichthyosis, X-linked | Subcortical Band Heterotopia | Raine Syndrome | Thanatophoric Dysplasia Type 1 | Oligoasthenoteratozoospermia | POEMS Syndrome | Xeroderma Pigmentosum Variant Type | Heterotopic Ossification | Hypercholesterolemia, Familial | Huntington's Disease | Cholangiocarcinoma | Tendinitis | Diabetic Nephropathy | Angioedema, Acquired | Mevalonate Kinase Deficiency | Macrophage Activation Syndrome | Inflammatory Joint Disease | Large Granular Lymphocytic Leukemia | Anterior Segment Dysgenesis | Mosaic Variegated Aneuploidy Syndrome 2 | Chondroma | Pupil Disorders | Hypothalamic Obesity | Heart Block | Aarskog-Scott Syndrome | Craniofrontonasal Syndrome | Alazami Syndrome | Early Infantile Epileptic Encephalopathy 4 | Microvillus Inclusion Disease | Hereditary Hemorrhagic Telangiectasia | Osteogenesis Imperfecta Type III | Angiosarcoma Of The Breast | X-linked Sideroblastic Anemia | Myasthenia | Guanidinoacetate Methyltransferase Deficiency | Emery-Dreifuss Muscular Dystrophy | Adams-Oliver Syndrome | Dysferlinopathy | Lymphoma, B-cell | Biotinidase Deficiency | Thrombotic Microangiopathy | Diabetes Insipidus | Vitamin B12 Deficiency | Smith-Kingsmore Syndrome | Myhre Syndrome | Membranous Nephropathy | Polymicrogyria | Toxic Epidermal Necrolysis | Coma | FG Syndrome | Pierre Robin Syndrome | Coronary Restenosis | Microcephaly, Seizures, And Developmental Delay | Oculopharyngeal Muscular Dystrophy | Panniculitis | Alcoholism | Primary Sclerosing Cholangitis | Pigment Dispersion Syndrome | Anorectal Fistula | Menkes Disease | Cyclic Vomiting Syndrome | Multiple Congenital Anomalies-hypotonia-seizures Syndrome 2 | Megalencephaly | Retinal Dystrophy | CHARGE Syndrome | Plasma Cell Leukemia | Schuurs-Hoeijmakers Syndrome | Congenital Hereditary Endothelial Dystrophy Type I | Growth Hormone Excess | Crimean-Congo Hemorrhagic Fever | Multisystemic Smooth Muscle Dysfunction Syndrome | Dysmorphophobia | Endometrial Hyperplasia | Sensory Neuropathy | Lipoma | Diabetes Mellitus, Transient Neonatal | Anal Fissure | Blood Protein Disorders | Pineoblastoma | Sengers Syndrome | Progressive Familial Intrahepatic Cholestasis Type 1 | Alveolar Capillary Dysplasia | Niemann-Pick Disease, Type A | Hypobetalipoproteinemias | Hyperphosphatasia With Intellectual Disability Syndrome 4 | Coloboma | Urofacial Syndrome | Stroke, Ischemic | Epidermolysis Bullosa Simplex With Mottled Pigmentation | Polycystic Ovary Syndrome | Polycystic Kidney, Autosomal Dominant | Rhinitis | Crouzon Syndrome With Acanthosis Nigricans | Unverricht-Lundborg Syndrome | Communication Disorders | Retinoblastoma | Eosinophilia | Familial Thoracic Aortic Aneurysm | Wiedemann-Steiner Syndrome | Congenital Dyserythropoietic Anemia Type 4 | Stomatitis | Dowling-Degos Disease | Spinal Muscular Atrophy Type 2 | Osteonecrosis Of The Jaw | Pemphigus | Hereditary Hemorrhagic Telangiectasia Type 2 | Brooke-Spiegler Syndrome | Neurogenic Bladder | Withdrawal Syndrome | Methemoglobinemia | Larsen Syndrome | Primary Progressive Nonfluent Aphasia | Achromatopsia | Hypopituitarism | Purpura | Esophagitis, Eosinophilic | Charcot-Marie-Tooth Disease, Type 2C | Toxoplasmosis | Amyotrophic Lateral Sclerosis, Juvenile | Coenzyme Q10 Deficiency | Acute Anterior Uveitis | Charcot-Marie-Tooth Disease Type 3 | Ovarian Hyperstimulation Syndrome | Pancytopenia | Osteitis | Osteonecrosis | Chronic Inflammatory Demyelinating Polyneuropathy | Spitz Nevus | Light Chain Amyloidosis | Fibrodysplasia Ossificans Progressiva | Cysticercosis | Alstrom Syndrome | Otopalatodigital Syndrome Type 2 | Nephrosclerosis | Major Depression | Molybdenum Cofactor Deficiency | Congenital Dyserythropoietic Anemia Type 1 | Sporadic Hemiplegic Migraine | Thin Basement Membrane Disease | Osteoporosis, Postmenopausal | Filariasis | Congenital Aniridia | Congenital Hypofibrinogenemia | Cerebrovascular Disorders | Odonto-onycho-dermal Dysplasia | Paraplegia | Pre-eclampsia | Weill-Marchesani Syndrome | Pneumococcal Meningitis | Periodontitis | Bethlem Myopathy | Hyperostosis | Incontinentia Pigmenti | Chitayat Syndrome | Joubert Syndrome 2 | Bladder Exstrophy | Congenital Adrenal Hyperplasia 1 | Dominant Optic Atrophy | Myoclonus-dystonia Syndrome | Congenital Sodium Diarrhea | Nail-Patella Syndrome | Nephrocalcinosis | Encephalopathy, Glycine | Spondylosis | Cellulitis | Chordoid Glioma | Maternally Inherited Diabetes And Deafness | Bursitis | Down Syndrome | Neovascular Glaucoma | Intermittent Claudication | Myotonic Disorders | Paracoccidioidomycosis | L-2-Hydroxyglutaric Aciduria | Tietze Syndrome | Hairy Cell Leukemia | Choriocarcinoma | Rheumatic Heart Disease | Diffuse Palmoplantar Keratoderma | Vitreoretinopathy, Proliferative | Epidermal Nevus Syndrome | Recurrent Respiratory Papillomatosis | Gastroschisis | Diffuse Intrinsic Pontine Glioma | Acrodysostosis | Kabuki Syndrome | Avian Influenza | Antisocial Personality Disorder | Glutaric Aciduria Type 1 | Amblyopia | Intestinal Hypomagnesemia 1 | Adenosine Deaminase 2 Deficiency | Mixed Connective Tissue Disease