Schnitzler Syndrome

About the Disease
Schnitzler Syndrome, also known as chronic urticaria with macroglobulinemia, is related to urticaria and exanthem, and has symptoms including rash An important gene associated with Schnitzler Syndrome is IL1R1 (Interleukin 1 Receptor Type 1), and among its related pathways/superpathways are Innate Immune System and Disease. The drugs Rilonacept and Dapansutrile have been mentioned in the context of this disorder. Affiliated tissues include bone, spleen and skin, and related phenotypes are splenomegaly and hepatomegaly

Common Targets
Interleukin-1 (nonspecified subtype) | IRAK4 | IL1B | NLRP3 Inflammasome | CRBN | IL6R | G114548

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