Disease

Osteogenesis Imperfecta Type I

About the Disease
Osteogenesis Imperfecta, Type I, also known as osteogenesis imperfecta type i, is related to osteogenesis imperfecta, type ix and osteogenesis imperfecta, type vii. An important gene associated with Osteogenesis Imperfecta, Type I is COL1A1 (Collagen Type I Alpha 1 Chain), and among its related pathways/superpathways are Collagen chain trimerization and Extracellular matrix organization. The drugs Pamidronic acid and Alendronic acid have been mentioned in the context of this disorder. Affiliated tissues include bone, eye and bone marrow, and related phenotypes are dentinogenesis imperfecta and osteopenia

Common Targets
COL1A1 | UBE3A | COL1A2 | COL5A2 | PRICKLE1 | IFITM5 | COL3A1

疾病靶点研报
Osteogenesis Imperfecta Type I

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