Osteogenesis Imperfecta Type I

About the Disease
Osteogenesis Imperfecta, Type I, also known as osteogenesis imperfecta type i, is related to osteogenesis imperfecta, type ix and osteogenesis imperfecta, type vii. An important gene associated with Osteogenesis Imperfecta, Type I is COL1A1 (Collagen Type I Alpha 1 Chain), and among its related pathways/superpathways are Collagen chain trimerization and Extracellular matrix organization. The drugs Pamidronic acid and Alendronic acid have been mentioned in the context of this disorder. Affiliated tissues include bone, eye and bone marrow, and related phenotypes are dentinogenesis imperfecta and osteopenia

Common Targets
COL1A1 | UBE3A | COL1A2 | COL5A2 | PRICKLE1 | IFITM5 | COL3A1

Note: If you'd like to get a target analysis report for Osteogenesis Imperfecta Type I, or if you are interested to learn how our AI-powered BDE-Chem can design therapeutic molecules to interact with the target(s) above against the disease of Osteogenesis Imperfecta Type I at a cost 90% lower than traditional approaches, please feel free to contact us at BD@silexon.ai.

Other Diseases

Orotic Aciduria | X-linked Charcot-Marie-Tooth Disease | Loeys-Dietz Syndrome | Blue Rubber Bleb Nevus Syndrome | Pneumonia, Mycoplasma | Hyperoxaluria | Nicolaides-Baraitser Syndrome | Osteoglophonic Dysplasia | Omenn Syndrome | Spinocerebellar Ataxia Type 28 | Polymyalgia Rheumatica | Cutaneous Mastocytosis | Neuroma | Autism Spectrum Disorders | Scapuloperoneal Myopathy, X-linked Dominant | Urethritis | Cerebrovascular Disorders | Leukodystrophies | Congenital Mirror Movements | Charcot-Marie-Tooth Disease Type 4B1 | Anal Fissure | Glycogen Storage Disease Type 6 | ADNP Syndrome | Chordoid Glioma | Mohr-Tranebjaerg Syndrome | Pathological Gambling | Van Der Knaap Disease | Malnutrition | Thyroid Hormone Resistance | Erdheim-Chester Disease | Shprintzen-Goldberg Syndrome | Pleural Tuberculosis | Riboflavin Transporter Deficiency Neuronopathy | Purpura | Mood Disorder | Ichthyosis | Prostatitis | Pseudo-pseudohypoparathyroidism | Osteochondrosis | Motion Sickness | Diastrophic Dysplasia | Polycythemia Vera | Dysferlinopathy | Nemaline Myopathy 8 | Epidermodysplasia Verruciformis | Depression | Methemoglobinemia | Bietti Crystalline Dystrophy | Anorectal Fistula | Ocular Hypertension | SAPHO Syndrome | Fetal And Neonatal Alloimmune Thrombocytopenia | Osteoarthritis | Apparent Mineralocorticoid Excess Syndrome | Polyneuropathy | Tremor | Cancer, Bladder | Esotropia | Presbycusis | Sensory Neuropathy | Phosphoglycerate Dehydrogenase Deficiency | Cholelithiasis | Niemann-Pick Disease, Type B | Hypertensive Retinopathy | Eiken Syndrome | DICER1 Syndrome | Ataxia-hypogonadism-choroidal Dystrophy Syndrome | Jaundice, Obstructive | Parkinsonism | Charcot-Marie-Tooth Disease, Type 6 | Fragile X Syndrome | Gyrate Atrophy Of The Choroid And Retina | Erythrokeratodermia Variabilis | Xeroderma Pigmentosum Variant Type | VACTERL Association | Anti-NMDA Receptor Encephalitis | Clouston Hidrotic Ectodermal Dysplasia | Chronic Myeloid Leukemia | Crigler-Najjar Syndrome | Sialidosis Type I | Crouzon Syndrome With Acanthosis Nigricans | Hyperphenylalaninemia | Angioimmunoblastic T-cell Lymphoma | Hypertension, Pulmonary | Leishmaniasis, Cutaneous | Genitopatellar Syndrome | Juvenile Polyposis | Anuria | Von Willebrand Disease | Saul-Wilson Syndrome | Hyperuricemic Nephropathy, Familial Juvenile | Lipid Storage Diseases | Hereditary Hemorrhagic Telangiectasia | Renal Failure | Early Infantile Epileptic Encephalopathy 13 | Zellweger Syndrome | Cri-du-chat Syndrome | Hypokalemic Periodic Paralysis | Lymphoma, Mantle Cell | Acute Lung Injury | Familial Cerebral Amyloid Angiopathy | Charcot-Marie-Tooth Disease Type 4 | Sialoadenitis | Carcinoid Syndrome | Guttate Psoriasis | Epidermolysis Bullosa Dystrophica | Lissencephaly 2 | Cardiac Arrest | Liver Diseases | Blastoma, Pleuropulmonary | Choriocarcinoma | Glaucoma, Congenital | Neuroendocrine Cancer | Takayasu's Arteritis | Goiter, Nodular | Kearns-Sayre Syndrome | WAGR Syndrome | Hyperlipidemia, Familial Combined | Rubeosis Iridis | Lymphoma, Follicular | Congenital Adrenal Hyperplasia | Familial Partial Lipodystrophy | Encephalitis | Choroiditis | Williams Syndrome | Retinal Diseases | Leprosy | Acne | Hepatitis A | Pigment Dispersion Syndrome | 3-methylglutaconic Aciduria Type IV | Primary Ovarian Insufficiency | FG Syndrome | Tyrosinemia Type 2 | Protein C Deficiency | Erythematotelangiectatic Rosacea | Varicocele | Joubert Syndrome | Benign Recurrent Intrahepatic Cholestasis 1 | Enhanced S-cone Syndrome | Chorea-acanthocytosis | Hepatitis, Autoimmune | Bursitis | Hypotrichosis, Congenital, With Juvenile Macular Dystrophy | Corneal Dystrophy And Perceptive Deafness | Corneal Dystrophy | Chronic Granulomatous Disease | Ophthalmia, Sympathetic | Microphthalmia | Familial Mediterranean Fever | Microcephalic Primordial Dwarfism | Esophageal Adenocarcinoma | Follicular Dendritic Cell Sarcoma | Atherosclerosis | Pyruvate Dehydrogenase Deficiency | Skin Carcinoma | Neurodegeneration With Brain Iron Accumulation | Dermatofibrosarcoma | Disseminated Intravascular Coagulation | Specific Granule Deficiency | Echinococcosis | Aldosterone Deficiency | Recurrent Respiratory Papillomatosis | Duchenne Muscular Dystrophy | Dyslexia | Chiari Malformation Type I | Hyper IgE Syndrome | Spinocerebellar Ataxia Type 13 | Meconium Ileus | Hereditary Multiple Exostoses | Toxic Epidermal Necrolysis | Spondylocostal Dysostosis | Chronic Kidney Disease | Erythema Multiforme | Rhabdomyosarcoma, Embryonal | Retinal Telangiectasia | T-cell Lymphoma, Subcutaneous Panniculitis-like | Tonsillitis | Paroxysmal Kinesigenic Dyskinesia | Lymphangiomatosis | Kidney Stones | Carcinoma, Transitional Cell | Vitamin B12 Deficiency | Glomerulonephritis, Membranoproliferative | Sarcosinemia | Cirrhosis | Sensorineural Hearing Loss | Sepiapterin Reductase Deficiency | Neurofibromatosis-Noonan Syndrome | Silicosis | Megacystis-microcolon-intestinal Hypoperistalsis Syndrome | Intermittent Explosive Disorder | Hyperferritinemia-cataract Syndrome | Multiple Sclerosis, Primary Progressive | Schuurs-Hoeijmakers Syndrome | Renal Hypomagnesemia 3 | Adenocarcinoma | Homocystinuria | Keratopathy | Niemann-Pick Disease | Rift Valley Fever | Acquired Partial Lipodystrophy | Xeroderma Pigmentosum | Premenstrual Syndrome | HUPRA Syndrome | Fanconi Anemia | Glaucomatocyclitic Crisis | Dystonia | Combined Deficiency Of Factor V And Factor VIII | Li-Fraumeni Syndrome | Intracranial Hypertension | Craniofrontonasal Syndrome | Cystinuria | Renal Hypouricemia | Ovarian Sex Cord-stromal Tumor | Coffin-Lowry Syndrome | Spondyloepimetaphyseal Dysplasia With Joint Laxity, Type 3 | Familial Hyperaldosteronism | Nanophthalmos | Gout | Kohlschutter-Tonz Syndrome | Neurofibroma, Plexiform | Branchiootorenal Syndrome | Coronary Restenosis | Supravalvular Aortic Stenosis | Cysticercosis | Onchocerciasis | Diabetes Type 1 | Ataxia-ocular Apraxia 2 | Pseudoachondroplasia | Heart Septal Defects | Majeed Syndrome | Parkinson Disease 6, Autosomal Recessive Early-onset | Ebstein Anomaly | Prune Belly Syndrome | Gardner Syndrome | Amebiasis | Cryptococcal Meningitis | Schwannomatosis | Relapsing Polychondritis | Maternally Inherited Diabetes And Deafness | Waardenburg Syndrome Type 4A | Sensory Ataxic Neuropathy, Dysarthria, And Ophthalmoparesis | Seborrheic Dermatitis | Pontocerebellar Hypoplasia Type 2 | Hereditary Sensory And Autonomic Neuropathy | Neurofibromatosis | Cockayne Syndrome | Hypertensive Nephropathy | Chylomicron Retention Disease | Pseudohypoparathyroidism Type 1B | Moyamoya Disease | Pierpont Syndrome | Cancer, Brain | Perivascular Epithelioid Cell Tumor | Overactive Bladder | Peripheral Neuropathy | Wagner Disease | Adrenal Insufficiency | Aphasia | Vulvovaginitis | Angiosarcoma Of The Breast | Noonan Syndrome-like Disorder With Loose Anagen Hair | Acral Lentiginous Melanoma | Ureteropelvic Junction Obstruction | Raynaud Phenomenon | Lyme Disease | Waardenburg Syndrome Type 2E | Epithelial-myoepithelial Carcinoma | Torticollis | Pantothenate Kinase-associated Neurodegeneration | Cranioectodermal Dysplasia | Trichomegaly | Gestational Trophoblastic Disease | Cardiofaciocutaneous Syndrome | Splenomegaly | Large Granular Lymphocytic Leukemia | Galloway-Mowat Syndrome | Benign Familial Pemphigus | Bare Lymphocyte Syndrome | Epilepsy | Heart Failure | Pneumonia, Viral | Epilepsy Of Infancy With Migrating Focal Seizures | Neuroectodermal Tumors, Primitive | Calcium Pyrophosphate Deposition Disease | Aneurysm, Abdominal Aortic | Tricho-hepato-enteric Syndrome | Stroke | Megaloblastic Anemia | Carcinoid Tumor | Corneal Dystrophies, Hereditary | Priapism | Open-angle Glaucoma | Congenital Heart Defects | Non-proliferative Diabetic Retinopathy | Alazami Syndrome | Cranial Nerve Disease | Hemochromatosis Type 1 | Hepatitis B, Chronic | Lennox-Gastaut Syndrome | Epidermolysis Bullosa Simplex | Hereditary Hemorrhagic Telangiectasia Type 2 | Spinocerebellar Ataxia Type 21 | Congenital Dysfibrinogenemia | Hypertrophy | Spinocerebellar Ataxia Type 5 | Withdrawal Syndrome | Inflammatory Myopathy | Panniculitis | Oculodentodigital Dysplasia | Sjogren Syndrome | Carpal Tunnel Syndrome | Arteriovenous Malformations | Enterocolitis, Necrotizing | Spina Bifida | Sorsby Fundus Dystrophy | Cellulitis | Microvillus Inclusion Disease | Medium-chain Acyl-CoA Dehydrogenase Deficiency | Bicuspid Aortic Valve | Periodontitis | Chondrodysplasia Punctata 2, X-linked Dominant | Congenital Torticollis | Seizures-scoliosis-macrocephaly Syndrome | Waardenburg Syndrome Type 2A | Thrombocytopenia | Sialidosis | Fibrosis | Adenoma, Pituitary | Primary Lateral Sclerosis | Veno-occlusive Disease | Transcobalamin Deficiency | Hypertrophic Osteoarthropathy, Primary, Autosomal Recessive 2 | Diabetes Insipidus, Nephrogenic | Pseudohypoparathyroidism Type 2 | DiGeorge Syndrome | Nijmegen Breakage Syndrome | Allan-Herndon-Dudley Syndrome | COACH Syndrome | Bethlem Myopathy | Smith-Magenis Syndrome | Blue Nevus | Polyradiculopathy | Sitosterolemia | Frontotemporal Dementia With Amyotrophic Lateral Sclerosis | Guillain-Barre Syndrome | Partington Syndrome | 3-methylcrotonyl-CoA Carboxylase Deficiency | Kabuki Syndrome 2 | Kawasaki Disease | IMAGe Syndrome | Ameloblastoma | Neurodevelopmental Disorder With Central Hypotonia And Dysmorphic Facies | Mitochondrial Encephalomyopathy | Osteopetrosis | Waardenburg Syndrome Type 1 | Microcephalic Osteodysplastic Primordial Dwarfism, Type I | Fascioliasis | Sleep Apnea, Central | Hypothyroidism | Noonan Syndrome | Best Macular Dystrophy | Antithrombin III Deficiency | Glycogen Storage Disease Type 3 | Progressive External Ophthalmoplegia | Dystrophy, Cone-rod | Pelvic Inflammatory Disease | Wolfram Syndrome | Galactosemia | Bone Giant Cell Tumor | Congenital Lipoid Adrenal Hyperplasia | Hypospadias | Retinoblastoma | Asphyxia Neonatorum | Episodic Ataxia | Papulopustular Rosacea | Hypoparathyroidism | B-cell Prolymphocytic Leukemia | Hypomyelination With Atrophy Of Basal Ganglia And Cerebellum | Epidermolysis Bullosa Simplex, Generalized | Infantile Neuroaxonal Dystrophy | Intestinal Tuberculosis | Transient Bullous Dermolysis Of The Newborn | Infantile Liver Failure Syndrome 1 | Endocarditis | Methemoglobinemia Type IV | Bruck Syndrome | Stevens-Johnson Syndrome | Oculopharyngeal Muscular Dystrophy | Potocki-Shaffer Syndrome | Mitochondrial Myopathy | Craniolenticulosutural Dysplasia | Myhre Syndrome | Alopecia | Fibronectin Glomerulopathy | Androgen Insensitivity | Tinea Versicolor | Primary Aldosteronism | B-cell Chronic Lymphocytic Leukemia