Disease

Sleep Disorder

About the Disease
Sleep Disorder, also known as sleep disorders, is related to narcolepsy 1 and idiopathic hypersomnia, and has symptoms including back pain, cachexia and cyanosis. An important gene associated with Sleep Disorder is HCRT (Hypocretin Neuropeptide Precursor), and among its related pathways/superpathways are IL-9 Signaling Pathways and Peptide hormone metabolism. The drugs Tramadol and Ketamine have been mentioned in the context of this disorder. Affiliated tissues include heart, brain and lung, and related phenotypes are no effect and no effect

Common Targets
ADRA2C | GPR55 | G5243 | SCN5A | Glutamate Receptor Ionotropic AMPA Receptor | HTR7 | CACNA1H | GPR139 | HRH3 | PROKR2 | G114548 | CSNK1E | Mitogen-activated protein kinase p38 (MAPK p38) (nonspecified subtype) | PDE4D | CACNA1B | HLA-DQB1 | 5-Hydroxytryptamine Receptor 3 (5-HT3 receptor) (nonspecified subtype) | Corticotropin-Releasing Factor (CRF) Receptor (nonspecified subtype) | LDLR | KCNC1 | KDR | AURKA | AVPR1A | G1956 | ABL1 | GRM5 | BMAL1 | AANAT | Tyrosine-Protein Kinases Src (nonspecified subtype) | CHRM4 | MTNR1A | Phosphodiesterase 1 (PDE1) (nonspecified subtype) | Gamma-Aminobutyric acid type B receptor | NPSR1 | MGLL | DRD4 | SLCO2B1 | AVPR1B | OPRM1 | ALOX12 | T-Type Calcium Channel | Alpha-2 Adrenergic receptors (nonspecified subtype) | GABRB2 | KCNC2 | CNR2 | GABRG2 | SIGMAR1 | CHRM1 | Casein kinase I (nonspecified subtype) | Calcium channel (nonspecified subtype) | HTR4 | HCRTR1 | KCNK2 | TYR | P2RX3 | CACNA1G | GRM2 | Protein kinase C (nonspecified subtype) | CLK4 | NF-kappaB (NFkB) | PDE9A | ADORA1 | CDK5 | Nicotinic alpha3beta4 Receptor | ADORA2B | SLC6A9 | TRPM8 | MAP3K14 | alpha-Adrenoceptor (nonspecified subtype) | NPY2R | TOP1 | HTR2B | Opioid receptor (nonspecified subtype) | SLC6A2 | HTR1A | HTR5A | DRD2 | MAPT-AS1 | CHRNA7 | UTS2R | CNR1 | BCHE | G4137 | MTNR1B | GABA(A) receptor | TRPV2 | ADRA2A | DYRK3 | HLA-DRB1 | DYRK1A | KCNQ Channels (K(v) 7) (nonspecified subtype) | OPRL1 | P2RX4 | Orexin receptor (nonspecified subtype) | K(ATP) Channel (nonspecified subtype) | ADORA2A | NPY5R | OXT | TRPV1 | Voltage-Gated Sodium Channel Complex | PTGDR | PTPN1 | XDH | ADORA3 | KCNK3 | TSPO | OPRD1 | GABRA1 | HCRTR2 | ACHE | VIPR2 | sigma Receptor (nonspecified subtype) | CSNK1A1 | PTGDR2 | NTRK1 | DRD1 | GSK3B | SOAT1 | Glycogen synthase kinase 3 (GSK-3) (nonspecified subtype) | G9429 | LINC02210-CRHR1 | PDE1B | G2475 | FAAH | GNRHR | G3630 | GRM3 | Cryptochrome (nonspecified subtype) | Sterol O-acyltransferase (ACAT) (nonspecified subtype) | Vasopressin Receptor (nonspecified subtype) | Sodium channel (nonspecified subtype) | PROKR1 | HTR6 | CRHR1 | Platelet-Derived Growth Factor Receptor (nonspecified subtype) | KCNK9 | Mitogen-Activated Protein Kinase (nonspecified subtype) | GABRD | CLK1 | Transglutaminase (nonspecified subtype) | RBM39 | SLC6A1 | NQO2 | TMEM97 | AP-1 Transcription Factor Complex | MAPK10 | NR1D2 | DYRK1B | 5-Hydroxytryptamine Receptor 2 (5-HT2) (nonspecified subtype) | HTR1B | G196 | NR3C1 | TH | SCN9A | alpha1-Adrenoceptor (nonspecified subtype) | SLC6A4 | TACR1 | GABRA2 | HRH1 | IL2 | NR1D1 | NMDA receptor | SOAT2 | Histamine Receptor (HR) (nonspecified subtype) | SGMS1 | GHRHR | APP | SLCO1B1 | CASP1 | SLCO1A2 | 5-Hydroxytryptamine Receptor (nonspecified subtype) | CSNK1D | NT5E | ADRA1B | DYRK2 | NOS2 | HTR2A | HTR2C | G4233 | VDR | TRPA1 | G5743 | CRHR2 | SLC29A1 | MCHR1 | TAAR1 | Potassium Channels (nonspecified subtype) | PRKCE | HTR1D | CLK2 | HRH4 | APOE | Voltage-Gated Calcium Channel alpha-2/delta (nonspecified subtype) | DRD3 | CHRM2 | ALOX5 | NLRP3 Inflammasome | SLC6A3 | OXTR | GABRA3 | FLT3 | G7124 | Proteasome Complex

疾病靶点研报
Sleep Disorder

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