Silver-Russell Syndrome

About the Disease
Silver-Russell Syndrome 1, also known as silver-russell syndrome, is related to silver-russell syndrome due to 11p15 microduplication and silver-russell syndrome due to an imprinting defect of 11p15. An important gene associated with Silver-Russell Syndrome 1 is IGF2 (Insulin Like Growth Factor 2). The drugs Anastrozole and Aromatase Inhibitors have been mentioned in the context of this disorder. Affiliated tissues include eye, bone and brain, and related phenotypes are short stature and prominent forehead

Common Targets
KMT2C | NAP1L5 | MEG3 | GRB10 | MBTPS1 | ZMYND11 | TGM1 | SNU13 | PADI6 | PPIEL | NLRP5 | HMGA2 | GET1 | PLAG1 | G3480 | IGFBP1 | SNRPN | PLAGL1 | ZNF597 | GNAS-AS1 | ORC1 | ZFP42 | IGFBP3 | DLK1 | BSCL2 | BLM | RB1 | ANKRD11 | OSBPL5 | NNAT | FAM50B | KCNQ1OT1 | FGD1 | ZFP57 | SNURF | ZNF331 | NLRP2 | DIRAS3 | MCTS2 | SGCE | MEST | IGF2 | H19 | H19-ICR | CDKN1C | L3MBTL1 | TRIM37

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