Hyperostosis

About the Disease
Hyperostosis, also known as hypertrophy of bone, is related to tumoral calcinosis, hyperphosphatemic, familial, 1 and diffuse idiopathic skeletal hyperostosis. An important gene associated with Hyperostosis is POLR3GL (RNA Polymerase III Subunit GL), and among its related pathways/superpathways are Signal Transduction and Signaling by Receptor Tyrosine Kinases. The drugs Pamidronic acid and Diphosphonates have been mentioned in the context of this disorder. Affiliated tissues include bone, bone marrow and spinal cord, and related phenotypes are homeostasis/metabolism and growth/size/body region

Common Targets
SLC39A14 | ACVR1

Note: If you'd like to get a target analysis report for Hyperostosis, or if you are interested to learn how our AI-powered BDE-Chem can design therapeutic molecules to interact with the target(s) above against the disease of Hyperostosis at a cost 90% lower than traditional approaches, please feel free to contact us at BD@silexon.ai.

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