Malignant Fibrous Histiocytoma

About the Disease
Fibrosarcoma of Bone, also known as malignant histiocytosis, is related to histiocytosis and histiocytic sarcoma, and has symptoms including fever and malaise. An important gene associated with Fibrosarcoma of Bone is SERPINA3 (Serpin Family A Member 3), and among its related pathways/superpathways are Innate Immune System and Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell. The drugs Cyclophosphamide and Etoposide have been mentioned in the context of this disorder. Affiliated tissues include bone, bone marrow and liver.

Common Targets
PCDHA8 | PIK3CA | G1956 | ATRX | H3-3B | UBR5 | G4609 | G4233 | G2064 | USP24 | G4193 | GRIA3 | ESRP2 | G7015 | RB1 | DUSP10 | G7157 | TTN | G472 | RTTN | DYNC2H1 | DOT1L | IPO9 | CD163L1 | Vascular endothelial growth factors (VEGF) (nonspecified subtype) | LRP2 | GAREM1 | MYCN | EEA1 | LIPF | H3-3A | RBM47

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