High Molecular Weight Kininogen Deficiency

About the Disease
High Molecular Weight Kininogen Deficiency, also known as hmwk deficiency, is related to factor xi deficiency and thrombosis. An important gene associated with High Molecular Weight Kininogen Deficiency is KNG1 (Kininogen 1), and among its related pathways/superpathways are Response to elevated platelet cytosolic Ca2+ and Collagen chain trimerization. Affiliated tissues include prostate, breast and salivary gland, and related phenotypes are prolonged partial thromboplastin time and reduced kininogen activity

Common Targets
KNG1

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