Lymphangioleiomyomatosis

About the Disease
Lymphangioleiomyomatosis, also known as lymphangiomyomatosis, is related to tuberous sclerosis 1 and tuberous sclerosis. An important gene associated with Lymphangioleiomyomatosis is TSC2 (TSC Complex Subunit 2), and among its related pathways/superpathways are ERK Signaling and GPCR Pathway. The drugs Doxycycline and Antimalarials have been mentioned in the context of this disorder. Affiliated tissues include lung, smooth muscle and skin, and related phenotypes are dyspnea and cough

Common Targets
mTOR complex 1 | TSC2 | RHEB | HRH1 | Proteasome Complex | CCR5 | GC | TOP2A | Vascular endothelial growth factors (VEGF) (nonspecified subtype) | FYN | CD19 | G2475 | Carbonic Anhydrase (nonspecified subtype) | ULK1 | G2099 | G5743

Note: If you'd like to get a target analysis report for Lymphangioleiomyomatosis, or if you are interested to learn how our AI-powered BDE-Chem can design therapeutic molecules to interact with the target(s) above against the disease of Lymphangioleiomyomatosis at a cost 90% lower than traditional approaches, please feel free to contact us at BD@silexon.ai.

Other Diseases

Aplastic Anemia | Insulinoma | Hemangioendothelioma | Heroin Dependence | Congenital Bilateral Absence Of Vas Deferens | Fraser Syndrome | Retinitis Pigmentosa | Pleomorphic Xanthoastrocytoma | Fanconi Syndrome | Multicystic Renal Dysplasia | Wiskott-Aldrich Syndrome | WAGR Syndrome | Cold Agglutinin Disease | Hypereosinophilic Syndrome | Smith-Magenis Syndrome | Primary Cutaneous Amyloidosis | Megaloblastic Anemia | Immunoproliferative Disorders | Diamond-Blackfan Anemia | Pelizaeus-Merzbacher Disease | Stromal Corneal Dystrophy | Hereditary Spherocytosis | Hepatopulmonary Syndrome | Trimethylaminuria | Ectrodactyly | Maple Syrup Urine Disease | Waardenburg Syndrome | Spinal And Bulbar Muscular Atrophy | Hypogonadism | Crohn's Disease | Arterial Tortuosity Syndrome | Photosensitivity | Meckel-Gruber Syndrome | Pituitary Stalk Interruption Syndrome | Adams-Oliver Syndrome | Mood Disorder | Corneal Neovascularization | Neuronal Ceroid Lipofuscinosis | Ophthalmia, Sympathetic | Malonyl-CoA Decarboxylase Deficiency | Metaphyseal Chondrodysplasia, Schmid Type | Adrenal Insufficiency | Colorectal Adenoma | Hemolytic Uremic Syndrome | Brachial Plexus Neuropathy | Mucolipidosis Type IV | Nemaline Myopathy 8 | Myofibromatosis | Myasthenia | McLeod Syndrome | Vitamin B12 Deficiency | Thyroid Dyshormonogenesis | Birk-Barel Syndrome | Sleep Apnea | Riboflavin Transporter Deficiency Neuronopathy | Lassa Fever | Pneumonia, Mycoplasma | Usher Syndrome | Mitochondrial DNA Depletion Syndrome, Myopathic Form | Sezary Syndrome | Cranial Nerve Disease | Anemia | Sarcoma, Endometrial Stromal | Endometritis | Gerodermia Osteodysplastica | Bladder Exstrophy | Huntington's Disease | Pre-eclampsia | Spinocerebellar Ataxia Type 20 | Keratoconjunctivitis | Polymyositis | Vici Syndrome | Urofacial Syndrome | Alexander Disease | Angioedema, Hereditary | Liver Diseases | Non-small Cell Lung Cancer | Oculopharyngeal Muscular Dystrophy | Dentinogenesis Imperfecta | Bronchiolitis | Frontometaphyseal Dysplasia | Primary Biliary Cholangitis | Frontotemporal Dementia With Amyotrophic Lateral Sclerosis | Hypertrophy | Congenital Muscular Dystrophy | Peeling Skin Syndrome Type B | Schizophrenia | Hepatoblastoma | Adult Polyglucosan Body Disease | Pontocerebellar Hypoplasia Type 2 | Angioimmunoblastic T-cell Lymphoma | Clouston Hidrotic Ectodermal Dysplasia | Shprintzen-Goldberg Syndrome | Tendinopathy | Lymphoma, Mantle Cell | Raine Syndrome | Fanconi Anemia | Cramp Fasciculation Syndrome | Ataxia-ocular Apraxia 2 | Mountain Sickness | Uremic Pruritus | Mucormycosis | Meningioma, Benign | Encephalopathy | Incontinentia Pigmenti | Coma | Hamartoma | Vitiligo | Bardet-Biedl Syndrome | Large Granular Lymphocytic Leukemia | Thymoma, Malignant | Headache | Otitis Media | Malaria | Juvenile Xanthogranuloma | Gray Platelet Syndrome | Keratocystic Odontogenic Tumor | Alzheimer Disease, Late Onset | Papilloma | Rubinstein-Taybi Syndrome | Follicular Dendritic Cell Sarcoma | Yellow Fever | Thalassemia, Beta | Cryptorchidism | ICF Syndrome | Uterine Leiomyoma | Proteus Syndrome | Bicuspid Aortic Valve | Cholesteryl Ester Storage Disease | Waldenstrom Macroglobulinemia | Left Ventricular Noncompaction | Antiphospholipid Syndrome | 3-hydroxy-3-methylglutaric Aciduria | Pseudoexfoliation Syndrome | 17-beta-hydroxysteroid Dehydrogenase X Deficiency | Pulmonary Vein Stenosis | B-cell Chronic Lymphocytic Leukemia | Blepharitis | Holoprosencephaly | Chronic Myelomonocytic Leukemia | Optic Neuritis | Congenital Hypofibrinogenemia | Thyroiditis | Mitochondrial Cytopathy | Polyneuropathy | Hypotrichosis, Congenital, With Juvenile Macular Dystrophy | Zimmermann-Laband Syndrome | Lewy Body Dementia | CEDNIK Syndrome | Atrioventricular Septal Defect | Spinal Muscular Atrophy Type 3 | Parkinson's Disease | Hemolytic Anemia | Pyloric Stenosis, Infantile Hypertrophic | Neurofibromatosis Type 1 | Crimean-Congo Hemorrhagic Fever | Ependymoma | Lipid Metabolism Disorders | Strabismus | Multifocal Motor Neuropathy | Blau Syndrome | Coenzyme Q10 Deficiency | Arthritis, Psoriatic | Blood Protein Disorders | Fahr Disease | Blastomycosis | Bipolar Disorder | Retinitis | Campomelic Dysplasia | Peripheral T-cell Lymphoma | Vaginitis | Xeroderma Pigmentosum Variant Type | Hypophosphatasia | Cohen Syndrome | Spinocerebellar Ataxia Type 31 | Autism | Cutis Laxa | Hereditary Neuropathy With Liability To Pressure Palsies | Barrett Esophagus | Dystonia Musculorum Deformans | Hyperferritinemia-cataract Syndrome | Rhizomelic Chondrodysplasia Punctata | Cryoglobulinemia | Glycogen Storage Disease Type 1b | Plasmacytoma | Mixed Connective Tissue Disease | Pigment Dispersion Syndrome | Postaxial Polydactyly | Facioscapulohumeral Muscular Dystrophy Type 1 | Knobloch Syndrome | Familial Retinal Arterial Macroaneurysm | Mandibuloacral Dysplasia With Type A Lipodystrophy | Intellectual Disability, Autosomal Dominant 5 | Dysthymia | Hartsfield Syndrome | Marinesco-Sjogren Syndrome | Macrophage Activation Syndrome | Cousin Syndrome | Congenital Adrenal Hyperplasia | Mesial Temporal Lobe Epilepsy With Hippocampal Sclerosis | Hyperparathyroidism | Bleeding Disorder Due To CalDAG-GEFI Deficiency | Idiopathic Pulmonary Fibrosis | Hereditary Sensory Neuropathy Type 1 | Creatine Deficiency Syndrome | Eosinophilia | Congenital Lipoid Adrenal Hyperplasia | Urea Cycle Disorder | Sick Sinus Syndrome 1 | Familial Mediterranean Fever | Thrombophlebitis | Sponastrime Dysplasia | Learning Disability | HUPRA Syndrome | Retinal Degeneration | Heart Block | FG Syndrome | Atelosteogenesis Type 1 | Gnathodiaphyseal Dysplasia | Primary Erythromelalgia | Arthritis, Gouty | Osteochondroma | Familial Episodic Pain Syndrome | Tatton-Brown-Rahman Syndrome | Megacystis-microcolon-intestinal Hypoperistalsis Syndrome | Hemimegalencephaly | Inflammatory Linear Verrucous Epidermal Nevus | Epilepsy, Generalized | Necrobiosis Lipoidica | Systemic Mastocytosis | Colitis | Encephalocele | Meniere's Disease | Lymphoma, Follicular | Cherubism | Hypertrophic Osteoarthropathy, Primary, Autosomal Recessive 2 | Nestor-Guillermo Progeria Syndrome | Oculocutaneous Albinism Type 2 | Spondyloarthritis | Sensory Ataxic Neuropathy, Dysarthria, And Ophthalmoparesis | Tetraplegia | Primary Lateral Sclerosis | Spinocerebellar Ataxia | Ollier Disease | Keratitis-ichthyosis-deafness Syndrome | H Syndrome | Sclerocornea | Congenital Aniridia | Neutropenia | Combined Malonic And Methylmalonic Acidemia | Geleophysic Dysplasia | Stomatitis | Iron Overload | Fibronectin Glomerulopathy | Fabry's Disease | Renal Oncocytoma | 3-methylglutaconic Aciduria Type I | Lymphoproliferative Disorders | Tylosis With Esophageal Cancer | Richter's Syndrome | Hypokalemic Periodic Paralysis | Spinal Cord Diseases | Leiomyoma | Poikiloderma With Neutropenia | Myelofibrosis | Pulmonary Stenosis | Angina Pectoris | Acute Anterior Uveitis | Galactosialidosis | Dystrophy, Cone-rod | Anxiety Disorders | Sarcoma | Goiter | Giant Cell Arteritis | Fatty Aldehyde Dehydrogenase Deficiency | Acute Kidney Injury | Lupus Erythematosus | Epidermolysis Bullosa Simplex, Generalized | Chronic Inflammatory Demyelinating Polyneuropathy | Lichen Sclerosus | Pyelonephritis | Pseudohypoaldosteronism | Homocystinuria | Gaze Palsy, Familial Horizontal, With Progressive Scoliosis, 2 | Rhabdomyosarcoma | Hyperekplexia | Cholestasis, Intrahepatic | Spasticity | Hereditary Folate Malabsorption | Glanzmann Thrombasthenia | Metabolic Syndrome | Prader-Willi Syndrome | Amyotrophic Lateral Sclerosis | Nail-Patella Syndrome | Osteosclerosis | Pneumonia, Bacterial | N-acetylglutamate Synthase Deficiency | Purpura | Diarrhea | Thyrotoxic Periodic Paralysis | VACTERL/VATER Association | Malignant Peripheral Nerve Sheath Tumor | Carpenter Syndrome | Diabetes Gestational | Mumps | Japanese Encephalitis | Congenital Dyserythropoietic Anemia Type 1 | IgA Nephropathy | Neurocutaneous Syndromes | Paraganglioma | Adenosine Deaminase Deficiency | Cardiomyopathy, Hypertrophic | Bullous Pemphigoid | Ureteropelvic Junction Obstruction | Ganglioglioma | Anti-glomerular Basement Membrane Disease | Metachromatic Leukodystrophy | Congenital Central Hypoventilation Syndrome | Lymphoma Lymphoblastic | Muscle Wasting | Treacher Collins Syndrome | Fucosidosis | Niemann-Pick Disease | Personality Disorders | Chondroma | Congenital Fiber-type Disproportion Myopathy | Leber Hereditary Optic Neuropathy | Familial Dysautonomia | Hepatitis A | Spinal Muscular Atrophy | Long QT Syndrome Type 1 | Hypospadias | Chronic Kidney Disease | Autosomal Recessive Spastic Paraplegia Type 75 | Ichthyosis | Ectodermal Dysplasia | Pneumococcal Meningitis | Thanatophoric Dysplasia Type 1 | Nephritis, Interstitial | Parvovirus B19 Infection | Renal-hepatic-pancreatic Dysplasia | Hypophosphatemic Rickets, Autosomal Recessive, 1 | Hypersomnia | Glycogen Storage Disease Type 0, Muscle | Schistosomiasis | Tumoral Calcinosis | Apraxia | Focal Facial Dermal Dysplasia | Colon Adenoma | Hypodontia | Agammaglobulinemia | Pemphigus Foliaceus | Hereditary Xerocytosis | Nephrotic Syndrome Type 1 | Phosphoglycerate Dehydrogenase Deficiency | Meningococcal Meningitis | Choriocarcinoma | Ocular Surface Squamous Neoplasia | Toxoplasmosis | Anal Fissure | PHARC Syndrome | Dyslipidemia | Fowler's Syndrome | Vitamin A Deficiency | Kashin-Beck Disease | Chondrodysplasia Punctata 2, X-linked Dominant | Zellweger Syndrome | Leishmaniasis, Cutaneous | Adenomatoid Tumor | Mucolipidosis | Sialoadenitis | Leukoplakia | Acute Lung Injury | Down Syndrome | Chondrosarcoma | Acrodermatitis Enteropathica | Saul-Wilson Syndrome | Methemoglobinemia Type IV | Emery-Dreifuss Muscular Dystrophy | Open-angle Glaucoma | Corneal Dystrophies, Hereditary | Major Depression | Histiocytosis | Amebiasis | Argininosuccinic Aciduria | Dermatitis | Anovulation | Dyggve-Melchior-Clausen Disease | Ehlers-Danlos Syndrome | Charcot-Marie-Tooth Disease, Type 2 | Autoimmune Polyendocrinopathy Syndrome Type I | Smith-Kingsmore Syndrome | Corneal Dystrophy And Perceptive Deafness | Tay-Sachs Disease | Acute Myeloid Leukemia | Hypervalinemia | Epiphyseal Chondrodysplasia, Miura Type | Patent Ductus Arteriosus | Polymyalgia Rheumatica | NDH Syndrome