Hemolytic Uremic Syndrome

About the Disease
Hemolytic-Uremic Syndrome, also known as hemolytic uremic syndrome, is related to nephrotic syndrome, type 7 and genetic atypical hemolytic-uremic syndrome. An important gene associated with Hemolytic-Uremic Syndrome is DGKE (Diacylglycerol Kinase Epsilon), and among its related pathways/superpathways are Innate Immune System and Diseases of hemostasis. The drugs Hematinics and Epoetin Alfa have been mentioned in the context of this disorder. Affiliated tissues include kidney, heart and endothelial, and related phenotypes are normal and homeostasis/metabolism

Common Targets
CFI | MMACHC | CFHR5 | F5 | C3 | CFH | C5AR1 | ERAP1 | HLA-DRB1 | MTHFR | C4BPA | CD46 | CFB | C5 | C8A

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