Patent Ductus Arteriosus

About the Disease
Patent Ductus Arteriosus 1, also known as patent ductus arteriosus, is related to aortic aneurysm, familial thoracic 4 and holt-oram syndrome. An important gene associated with Patent Ductus Arteriosus 1 is FLNA (Filamin A), and among its related pathways/superpathways are Cardiac conduction and Human Embryonic Stem Cell Pluripotency. The drugs Beractant and Poractant alfa have been mentioned in the context of this disorder. Affiliated tissues include heart, lung and brain, and related phenotypes are patent ductus arteriosus and nervous system

Common Targets
TRAF1 | PRDM6 | TBX1 | SERPINE2 | TGFBR1 | LOC105377462 | MYH11 | PPP2R1A | HHIP | NF-kappaB (NFkB) | PTGIS | SERPINB1 | PTGDR2 | NOX3 | CREBBP | TFAP2B | FGF10 | CYP2C9 | SOD3 | NADPH Oxidase Complex | MYOCD | LOC107984256 | ASIC1 | SYN1 | CITED2 | NADPH Oxidase (nonspecified subtype) | TGFBR2 | NKX2-6 | EPAS1 | EDNRA | ACTA2 | G5743 | ISL1 | PTGS1

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