Vitamin K Deficiency

About the Disease
Vitamin K Deficiency Bleeding, also known as vitamin k deficiency, is related to vitamin k-dependent clotting factors, combined deficiency of, 2 and vitamin k-dependent clotting factors, combined deficiency of, 1. An important gene associated with Vitamin K Deficiency Bleeding is F2 (Coagulation Factor II, Thrombin), and among its related pathways/superpathways are Metabolism of proteins and Response to elevated platelet cytosolic Ca2+. The drugs Dabigatran and Edoxaban have been mentioned in the context of this disorder. Affiliated tissues include kidney, liver and bone, and related phenotypes are no effect and no effect

Common Targets
GGCX

Note: If you'd like to get a target analysis report for Vitamin K Deficiency, or if you are interested to learn how our AI-powered BDE-Chem can design therapeutic molecules to interact with the target(s) above against the disease of Vitamin K Deficiency at a cost 90% lower than traditional approaches, please feel free to contact us at BD@silexon.ai.

Other Diseases

Epidermolysis Bullosa Simplex With Mottled Pigmentation | Klinefelter Syndrome | Nijmegen Breakage Syndrome | Partington Syndrome | Primary Torsion Dystonia | Hypertension, Essential | Infantile Spasm | Charcot-Marie-Tooth Disease, Type 2A | Triphalangeal Thumb-polysyndactyly Syndrome | Hypersensitivity | Osteoporosis, Postmenopausal | Astigmatism | Epidermolytic Ichthyosis, Annular | Optic Nerve Hypoplasia, Bilateral | Hydrocephalus | Vitamin A Deficiency | Arterial Tortuosity Syndrome | Tremor | Ganglioglioma | Muscle Wasting | Asplenia | Eccrine Porocarcinoma | Coma | Irritable Bowel Syndrome | Geleophysic Dysplasia | Orthostatic Intolerance | Reticular Dysgenesis | Fibrodysplasia Ossificans Progressiva | Syndactyly | Molybdenum Cofactor Deficiency | Spondyloepiphyseal Dysplasia Tarda, X-linked | NDH Syndrome | Kohlschutter-Tonz Syndrome | Megalencephaly | Fetal And Neonatal Alloimmune Thrombocytopenia | Pituitary Stalk Interruption Syndrome | Thrombophilia | Isovaleric Acidemia | Nutrition Disorders | Impetigo | 6-pyruvoyl-tetrahydropterin Synthase Deficiency | Retinopathy Of Prematurity | Multiple Sclerosis, Secondary Progressive | Angelman Syndrome | Mitochondrial DNA Depletion Syndrome 13 | Synpolydactyly | Generalized Epilepsy And Paroxysmal Dyskinesia | Sialoadenitis | Stuttering | Spondyloarthritis | Charcot-Marie-Tooth Disease Type 4D | Cystinosis | Schizencephaly | Spondyloepimetaphyseal Dysplasia With Joint Laxity, Type 3 | Vascular Calcification | Congenital Hereditary Endothelial Dystrophy Type I | VACTERL Association | Aicardi-Goutieres Syndrome | Hepatitis D | Oligoasthenoteratozoospermia | Adrenal Insufficiency | Chorea-acanthocytosis | Guillain-Barre Syndrome | Hypoalbuminemia | Hypotonia-cystinuria Syndrome | Takayasu's Arteritis | Corticobasal Syndrome | Guttate Psoriasis | Lissencephaly 2 | Keloid | Hemosiderosis | Lymphangioleiomyomatosis | Pyruvate Decarboxylase Deficiency | Exfoliative Dermatitis | Long QT Syndrome Type 3 | Microvillus Inclusion Disease | Spinocerebellar Ataxia Type 14 | Cholelithiasis | Focal Facial Dermal Dysplasia | Thanatophoric Dysplasia Type 1 | Mast Cell Leukemia | Kleine-Levin Syndrome | Poikiloderma With Neutropenia | Depression | Yellow Fever | Sandhoff Disease | Lattice Corneal Dystrophy Type 1 | Waardenburg Syndrome Type 2A | Epidermolysis Bullosa Simplex, Generalized | Microphthalmia, Syndromic 7 | Hypotrichosis, Congenital, With Juvenile Macular Dystrophy | Retinal Vasculitis | Spinocerebellar Ataxia Type 10 | Hashimoto Thyroiditis | Immunoproliferative Disorders | Stroke | Periventricular Leukomalacia | Osteogenesis Imperfecta | Marfan Syndrome | Neurodevelopmental Disorders | Pontocerebellar Hypoplasia Type 7 | Periodontitis | Niemann-Pick Disease | Leukemia | REM Sleep Behavior Disorder | Klippel-Feil Syndrome | Gastric Atrophy | Congenital Myopathy | Benign Familial Pemphigus | Pancreatitis, Chronic | Carcinoma, Transitional Cell | Cutaneous Lupus Erythematosus | Anencephaly | Spinocerebellar Ataxia Type 20 | Hyperacusis | B-cell Chronic Lymphocytic Leukemia | Hemorrhagic Disorders | Mitochondrial DNA Depletion Syndrome, Encephalomyopathic Form | Vestibular Disease | Retinoblastoma | Hypermethioninemia | Multisystemic Smooth Muscle Dysfunction Syndrome | Panniculitis | Protein S Deficiency | Hermansky-Pudlak Syndrome | Carotid Artery Disease | POEMS Syndrome | Corneal Dystrophy | Babesiosis | Learning Disability | Congenital Heart Block | Cutaneous T-cell Lymphoma | Apraxia | PHARC Syndrome | Uveitis | Leishmaniasis, Visceral | Renal Failure | Craniofacial Dysostosis | Spinocerebellar Ataxia Type 5 | Raynaud Phenomenon | Anxiety Disorders | Skin Fragility-woolly Hair Syndrome | Dyskeratosis Congenita | Oculocutaneous Albinism | Contact Dermatitis | Lipoma | Familial Hemiplegic Migraine | Bronchiolitis | Deafness, Dystonia, And Cerebral Hypomyelination | IMAGe Syndrome | Sickle Cell Disease | Multiple Hamartoma Syndrome | Hyperparathyroidism-jaw Tumor Syndrome | Glomerulonephritis, Membranous | Keratoconjunctivitis | Rolandic Epilepsy | Uremic Pruritus | Ehlers-Danlos Syndrome With Progressive Kyphoscoliosis, Myopathy, And Hearing Loss | Autosomal Recessive Spastic Paraplegia Type 35 | Cataract | Chordoma | Gastroenteritis | Fibromyalgia | Neurogenic Bladder | Metabolic Diseases | Kindler Syndrome | Syncope | Hepatopulmonary Syndrome | Amyloidosis | Congenital Ichthyosiform Erythroderma | Tylosis With Esophageal Cancer | Renpenning Syndrome | Meningococcal Meningitis | Varices | Discoid Lupus Erythematosus | Loeys-Dietz Syndrome Type 4 | Glycogen Storage Disease | Desbuquois Syndrome | Adenosine Deaminase 2 Deficiency | Bare Lymphocyte Syndrome | Basal Ganglia Cerebrovascular Disease | Dubin-Johnson Syndrome | Nephritis, Interstitial | Mosaic Variegated Aneuploidy Syndrome 2 | Adenosine Deaminase Deficiency | Epiphyseal Chondrodysplasia, Miura Type | Cluster Headache | Anorectal Malformations | Colitis, Collagenous | Intermittent Explosive Disorder | Colitis, Lymphocytic | Krabbe Disease | Tinea Versicolor | Polycystic Liver | Hyperbilirubinemia | Leber Congenital Amaurosis | Tay-Sachs Disease | Atopic Dermatitis | Hyperlipidemia | Usher Syndrome | Hereditary Inclusion Body Myopathy | Charcot-Marie-Tooth Disease, Type 2 | IgA Deficiency | Infantile Liver Failure Syndrome 1 | Microphthalmia | Asthma | Achondrogenesis | Acromesomelic Dysplasia | Genitopatellar Syndrome | Vitamin B12 Deficiency | Papilloma | Cockayne Syndrome | Osteosclerosis | Otopalatodigital Syndrome Type 2 | Congenital Diaphragmatic Hernia | Meckel-Gruber Syndrome | Neurofibromatosis Type 2 | Hypotension, Orthostatic | Reye Syndrome | Rift Valley Fever | Corneal Ulcer | Carcinoma, Squamous Cell | Hypercholesterolemia | Lipid Storage Diseases | Hypokalemia | Hypohidrotic Ectodermal Dysplasia | Mitochondrial Disease | Silver-Russell Syndrome | Dental Caries | Cerebral Amyloid Angiopathy | Chorea | Senior-Loken Syndrome | Cancer, Bladder | Endocarditis | Hartsfield Syndrome | Kernicterus | Primary Sclerosing Cholangitis | Spitzoid Melanoma | Neuroblastoma | Hypertension, Renovascular | X-linked Myotubular Myopathy | Polyneuropathy | Anovulation | Congenital Tufting Enteropathy | Ocular Hypertension | Lymphedema | Coloboma | Potocki-Shaffer Syndrome | Menkes Disease | Hypoparathyroidism | Protein C Deficiency | CHARGE Syndrome | Tatton-Brown-Rahman Syndrome | Vitreoretinal Degeneration, Snowflake Type | Hypertrophic Osteoarthropathy, Primary, Autosomal Recessive 1 | Poirier-Bienvenu Neurodevelopmental Syndrome | Ameloblastoma | Mevalonate Kinase Deficiency | Spinocerebellar Ataxia Type 38 | Alpers Syndrome | Glutaric Aciduria Type 3 | Ischemia | Congenital Dyserythropoietic Anemia Type 1 | Alopecia | Familial Exudative Vitreoretinopathy | Myelodysplasia | Encephalopathy, Glycine | Hypertrophic Osteoarthropathy, Primary, Autosomal Recessive 2 | Pseudoachondroplasia | Goiter | Polyarteritis Nodosa | Bullous Pemphigoid | Osteonecrosis Of The Jaw | Myelitis, Transverse | Wolman Disease | Choriocarcinoma | Parkinson's Disease | Pulmonary Tuberculosis | Hennekam Lymphangiectasia-lymphedema Syndrome | Sensory Neuropathy | Tuberculous Meningitis | Fascioliasis | Hemochromatosis Type 2 | Cervical Dystonia | Pitt-Hopkins Syndrome | Preaxial Polydactyly | Smith-Magenis Syndrome | Lewy Body Dementia | Leri Pleonosteosis | Colitis | Leukocyte Adhesion Deficiency Type 1 | Myoclonus | Multiple Sclerosis | Tendinopathy | Incontinentia Pigmenti | Alopecia Totalis | Congenital Absence Of Vas Deferens | Hepatoblastoma | Eiken Syndrome | Heroin Dependence | Adams-Oliver Syndrome | Meniere's Disease | Basal Ganglia Disease | Epidermal Nevus Syndrome | Congenital Bile Acid Synthesis Defect | Batten Disease | Familial Hyperaldosteronism | Giant Axonal Neuropathy | CDKL5 Deficiency Disorder | Ghosal Syndrome | Myocardial Infarction | Keratosis, Actinic | Sponastrime Dysplasia | Pulmonary Sclerosing Hemangioma | Raine Syndrome | Carbonic Anhydrase VA Deficiency | Muir-Torre Syndrome | Keratitis | Periodic Limb Movement Disorder | Blepharophimosis Syndrome | Hydrocephalus, Normal Pressure | Aspartylglycosaminuria | Tardive Dyskinesia | Chitayat Syndrome | Hypersomnia | Pheochromocytoma | Congenital Aniridia | Sclerosing Cholangitis | Congenital Myasthenic Syndrome | Intestinal Pseudo-obstruction | Facioscapulohumeral Muscular Dystrophy | Crohn's Disease | Cardiomyopathy, Hypertrophic | Communication Disorders | Wolff-Parkinson-White Syndrome | Spinocerebellar Ataxia Type 13 | Otitis Media | Myoclonus-dystonia Syndrome | Micropenis | Evans Syndrome | Bietti Crystalline Dystrophy | Cushing Syndrome | C3 Glomerulonephritis | Hemorrhage | Nasodigitoacoustic Syndrome | Mucolipidosis Type II | Asthma, Nocturnal | Pseudohypoaldosteronism | Acute Kidney Injury | Norrie Disease | Myasthenia Gravis | Cerebrovascular Disorders | Charcot-Marie-Tooth Disease Type 3 | Spinocerebellar Ataxia Type 7 | Histiocytic Sarcoma | Scleroderma, Diffuse | Charcot-Marie-Tooth Disease Type 4E | Oligospermia | Papilledema | Antisocial Personality Disorder | Pneumoconiosis | Parvovirus B19 Infection | Hypolipoproteinemia | Spinocerebellar Ataxia Type 2 | Diffuse Idiopathic Pulmonary Neuroendocrine Cell Hyperplasia | Renal Tubular Acidosis | Chudley-McCullough Syndrome | Blue Nevus | Supravalvular Aortic Stenosis | Agammaglobulinemia | Spinal Cord Diseases | Spinocerebellar Ataxia | Werner's Syndrome | Hodgkin Lymphoma | Peripheral Neuropathy | Borjeson-Forssman-Lehmann Syndrome | Dementia, Vascular | Shwachman-Bodian-Diamond Syndrome | Cryopyrin-associated Periodic Syndromes | Cervicitis | Creatine Deficiency Syndrome | Hyperuricemic Nephropathy, Familial Juvenile | Cannabis Abuse | Metatropic Dysplasia | Facioscapulohumeral Muscular Dystrophy Type 1 | Hamartoma | Papillorenal Syndrome | Sporadic Inclusion Body Myositis | Phenylketonuria | Mitochondrial Cytopathy | Cancer, Skin | Proopiomelanocortin Deficiency | Carey-Fineman-Ziter Syndrome | Infertility, Male | Cenani-Lenz Syndactyly Syndrome | Heart Failure | Von Willebrand Disease | Parkinson Disease 6, Autosomal Recessive Early-onset | Pure Red Cell Aplasia | Pseudohypoparathyroidism Type 2