Angiosarcoma

About the Disease
Angiosarcoma, also known as hemangiosarcoma, is related to liver angiosarcoma and breast angiosarcoma. An important gene associated with Angiosarcoma is KRAS (KRAS Proto-Oncogene, GTPase), and among its related pathways/superpathways are Signal Transduction and ERK Signaling. The drugs Ethiodized oil and Ifosfamide have been mentioned in the context of this disorder. Affiliated tissues include endothelial, skin and liver, and related phenotypes are Decreased viability and Decreased viability

Common Targets
NPM1 | RET | G5594 | G7157 | CIC | G7015 | ENG | TSC2 | TNC | GNAQ | ANGPT2 | Reverse transcriptase (Telomerase) | SOX2 | RAF1 | IL-2 receptor | TEK | AMER1 | CUL4B | G673 | APC | NSD1 | NF1 | MGMT | PTPN11 | G5133 | POT1 | TOP2A | CUL3 | PLCG1 | G1029 | BCL2L2 | G238 | PTPRB | G2475 | ARID1A | G5728 | G29126 | G5243 | BIRC5 | LRP1B | TGFBR2 | MYCN | NRAS | PIK3CA | ANGPT1 | RPA1 | BRCA2 | HRAS | G207 | FGFR3 | MED12 | GNA11 | Heat shock protein 90 (nonspecified subtype) | Tubulin | RAD51B | IL2RB | KDR | STAG2 | G4233 | FLT4 | EPHB1 | NF2 | KMT2C | G4851 | MAP2K1 | RAD54L | G4609 | G3845 | SFRP2

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