Disease

Pernicious Anemia

About the Disease
Pernicious Anemia, also known as anemia, pernicious, is related to diphyllobothriasis and congenital intrinsic factor deficiency, and has symptoms including fatigue An important gene associated with Pernicious Anemia is CBLIF (Cobalamin Binding Intrinsic Factor), and among its related pathways/superpathways are Metabolism of water-soluble vitamins and cofactors and "Cobalamin (Cbl, vitamin B12) transport and metabolism". The drugs Mecobalamin and Hydroxocobalamin have been mentioned in the context of this disorder. Affiliated tissues include bone marrow, spinal cord and liver, and related phenotypes are megaloblastic anemia and malabsorption of vitamin b12

Common Targets
IL2RA | PHTF1 | CBLIF | PPP4R3B | AIRE | HLA-DQB1-AS1

疾病靶点研报
Pernicious Anemia

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