Disease

Dyslexia

About the Disease
Alexia, also known as dyslexia, acquired, is related to progressive non-fluent aphasia and inclusion body myopathy with paget disease of bone and frontotemporal dementia, and has symptoms including scanning speech and aprosodia. An important gene associated with Alexia is MAPT (Microtubule Associated Protein Tau), and among its related pathways/superpathways are Alzheimer's disease and miRNA effects and Signaling by Receptor Tyrosine Kinases. The drugs Levodopa and Atomoxetine have been mentioned in the context of this disorder. Affiliated tissues include brain, cortex and eye, and related phenotypes are nervous system and homeostasis/metabolism

Common Targets
DNAAF4-CCPG1 | PAH | CDK5 | CHRNA7 | DBH | DIP2A | TDP2 | FOXP2 | ARL17A | BLM | LRRC37A | NSF | NTN1 | CYP19A1 | NSFP1 | LRRC37A2 | IRF6 | CEP63 | DCDC2 | S100B | LOC730100 | KIAA0319 | MRPL19 | DNAAF4 | COMT | KANSL1-AS1 | OTUD7A | MAOA | LYPD5 | TNFRSF1B | KANSL1 | FGF18

疾病靶点研报
Dyslexia

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