Multiple System Atrophy

About the Disease
Multiple System Atrophy 1, also known as multiple system atrophy, is related to pure autonomic failure and olivopontocerebellar atrophy. An important gene associated with Multiple System Atrophy 1 is COQ2 (Coenzyme Q2, Polyprenyltransferase), and among its related pathways/superpathways are Neuroscience and Neural Stem Cells and Lineage-specific Markers. The drugs Acetylcholine and Zoledronic acid have been mentioned in the context of this disorder. Affiliated tissues include Limb and Bone, and related phenotypes are abnormal pyramidal sign and dysarthria

Common Targets
LOC105377329 | ADORA1 | ABI3 | PDXK | LAG3 | C9orf72 | ICAM1 | ADORA2A | ELOVL7 | XDH | LOC105370616 | LOC105370617 | GPNMB | CELF1 | NDUFV1 | SHMT2 | ARHGAP44 | HTR2A | NF-kappaB (NFkB) | RASGRP3 | FBN2 | SMPD1 | FBXO47 | G4137 | NMDA receptor | SLC19A1 | RNASEH1 | TSPO | THSD7B | VHL | IL1A | DRD1 | FERMT2 | LINGO1 | Amyloid beta A4 precursor protein-binding family (APP-BP) (nonspecified subtype) | FABP3 | PTK2B | LOC105374187 | BIN3 | APOE | LMX1B | G3576 | PINK1 | G5133 | ASB1 | SLC6A19 | CARD6 | LINC02210-CRHR1 | ABL1 | 5-Hydroxytryptamine Receptor 2 (5-HT2) (nonspecified subtype) | PDE1B | NUAK1 | OGA | S1PR5 | SLC6A3 | MAOB | CSF1R | APOL1 | FAF1 | G2475 | HTT | ATXN1 | MDGA2 | NAP1L4 | ZIC2 | GRIN2B | MPO | PRKN | G6647 | PALS2 | STK39 | GRN | ATXN2 | SCN2A | RRBP1 | GPR65 | Major histocompatibility complex class II antigens (nonspecified subtype) | RREB1 | GALC | LRRK2 | SNCA | FGL1 | PRNP | RIPK2 | G7124 | WNT3 | COQ2 | CDH4 | SLC6A2 | Protein Kinase B (PKB/Akt) (nonspecified subtype) | PLCG2 | CASC16 | SREBF1 | Protein Phosphatase 2A | Alpha-2 Adrenergic receptors (nonspecified subtype) | RAB29 | LINGO2 | SIRT2 | PDYN | SPPL2B | SLC18A2 | GBA1 | SLC9A1 | SIGMAR1 | IL1B

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