Disease

Congenital Diaphragmatic Hernia

About the Disease
Diaphragmatic Hernia, Congenital, also known as congenital diaphragmatic hernia, is related to microphthalmia, syndromic 12 and donnai-barrow syndrome. An important gene associated with Diaphragmatic Hernia, Congenital is GATA6 (GATA Binding Protein 6), and among its related pathways/superpathways are G-protein signaling_Rap2B regulation pathway and Development of ureteric collection system. The drugs Nitric Oxide and Sildenafil have been mentioned in the context of this disorder. Affiliated tissues include lung, heart and fetal lung, and related phenotypes are congenital diaphragmatic hernia and intestinal malrotation

Common Targets
GATA4 | LAMB1 | RLIM | MYH11 | PTPN12 | GATA6 | CDO1 | DSEL | FREM1 | PLPP6 | PLAT | LONP1 | DISP1 | ZFPM2 | DLST | INHBB | KMT2D | PIGN | NR2F2 | ARFGEF2 | CLCN4 | FGFRL1 | SIN3A | PORCN | FRAS1 | MYRF | FREM2 | SLC5A9 | STAG2 | SOX7 | PRKACB | FBN1

疾病靶点研报
Congenital Diaphragmatic Hernia

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