Guillain-Barre Syndrome

About the Disease
Guillain-Barre Syndrome, also known as guillain-barré syndrome, is related to chronic inflammatory demyelinating polyradiculoneuropathy and miller fisher syndrome, and has symptoms including back pain, headache and neuralgia. An important gene associated with Guillain-Barre Syndrome is PMP22 (Peripheral Myelin Protein 22), and among its related pathways/superpathways are Cytokine Signaling in Immune system and IL-9 Signaling Pathways. The drugs Eculizumab and Complement System Proteins have been mentioned in the context of this disorder. Affiliated tissues include spinal cord, brain and heart, and related phenotypes are acute demyelinating polyneuropathy and hyporeflexia

Common Targets
G4318 | PMP22 | ICAM1 | DHODH | G7124 | CD1A | CCR2 | G3605 | TLR2 | FCGR3A | GM1 ganglioside | ITK | PLG | TLR9 | FASN | FASLG | Interferon alpha/beta Receptor (nonspecified subtype) | CLCN1 | IL17F | CRBN | G7099 | FCGR2A | AGTR2 | Potassium Channels (nonspecified subtype) | C6 | MSR1 | RORC | FCGR3B | TLR3 | CD1E | NR3C1 | C5 | Complement component 1q | EPHX2

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