Disease

Myasthenia Gravis

About the Disease
Myasthenia Gravis, also known as mg, is related to neonatal myasthenia gravis and myasthenic syndrome, congenital, 6, presynaptic, and has symptoms including ptosis, diplopia and dysphagia. An important gene associated with Myasthenia Gravis is AKAP12 (A-Kinase Anchoring Protein 12), and among its related pathways/superpathways are Overview of interferons-mediated signaling pathway and NF-kappaB Signaling. The drugs Salbutamol and Eculizumab have been mentioned in the context of this disorder. Affiliated tissues include thymus, eye and skeletal muscle, and related phenotypes are ptosis and diplopia

Common Targets
IKZF1 | PSMB5 | Folate Receptor (nonspecified subtype) | G0S2 | VDR | G3630 | GDF11 | RSBN1 | Uncharacterized LOC101928822, transcript variant X1 | CFD | G598 | G7124 | PPP3R2 | CTSS | FCGRT | TNFSF13 | TPMT | IL10 | PPP3CC | MIR155 | CTPS1 | CD40 | PPID | CHRNA7 | BCHE | TNFSF13B | TNNI2 | CD38 | LINC01149 | CTLA4 | G4170 | CD86 | DNMT3B | Skeletal muscle troponin | TLR9 | ADA | MS4A1 | NMDA receptor | IL12RB2 | Adenosine deaminase (nonspecified subtype) | IL2 | STAT4 | ADRB2 | LOC105375922 | TNNT3 | JAK1 | CXCR3 | ROCK2 | AP4B1-AS1 | CLCN1 | Complement Complex | PTPN22 | TNFRSF11A | CD80 | TGFB1 | HLA-DQB1 | C3 | G5133 | PPP3CB | CHAT | Potassium Channels (nonspecified subtype) | IL6R | ABCC6 | PPP3R1 | HLA-C | G6774 | PIK3CG | MSTN | TNFRSF13C | TNFRSF17 | Inosine 5'-monophosphate dehydrogenase (IMPDH) (nonspecified subtype) | AIRE | DHFR | CD19 | MAOB | S1PR1 | G29126 | HLA-DRB1 | ACE | HCAR2 | BTK | alpha-6 beta-2 Nicotinic receptor | G4780 | Nicotinic alpha3alpha6beta2 Receptor | FOXP3 | HLA-B | PIK3CA | Protein Phosphatase 2B | CD3 Complex (T Cell Receptor Complex) | PPIA | TYK2 | 5-Hydroxytryptamine Receptor 3 (5-HT3 receptor) (nonspecified subtype) | CHRNA1 | G2099 | C5 | PIK3CD | HLA-DQA1 | Complement component 1q | ACHE | FKBP1A

疾病靶点研报
Myasthenia Gravis

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