Hartnup Disease

About the Disease
Hartnup Disorder, also known as hartnup disease, is related to aminoaciduria and cystinuria, and has symptoms including seizures An important gene associated with Hartnup Disorder is SLC6A19 (Solute Carrier Family 6 Member 19), and among its related pathways/superpathways are Disease and Transport of inorganic cations/anions and amino acids/oligopeptides. Affiliated tissues include Kidney, skin and cerebellum, and related phenotypes are hyperreflexia and eeg abnormality

Common Targets
SLC6A19

Note: If you'd like to get a target analysis report for Hartnup Disease, or if you are interested to learn how our AI-powered BDE-Chem can design therapeutic molecules to interact with the target(s) above against the disease of Hartnup Disease at a cost 90% lower than traditional approaches, please feel free to contact us at BD@silexon.ai.

Other Diseases

Contact Dermatitis | Richter's Syndrome | Bernard-Soulier Syndrome | Progressive Familial Intrahepatic Cholestasis | Waardenburg Syndrome Type 2A | Microphthalmia, Syndromic 7 | Silver-Russell Syndrome | Eczema | Varicocele | Diabetes | Von Willebrand Disease | Renal Hypomagnesemia 3 | Acute Myeloid Leukemia | Epidermolysis Bullosa Simplex, Generalized | Spondylo-ocular Syndrome | Corneal Neovascularization | Early Infantile Epileptic Encephalopathy 13 | Porphyria | Protein S Deficiency | T-cell Prolymphocytic Leukemia | Hidradenitis Suppurativa | Central Core Disease | Autosomal Recessive Spastic Paraplegia Type 75 | Renal Failure | Major Depression | H Syndrome | Acrodermatitis | Osteoporosis | Sporadic Hemiplegic Migraine | Carney-Stratakis Syndrome | Sensorineural Hearing Loss | Polycythemia | Avellino Corneal Dystrophy | Hyperglycemia | Epidermolysis Bullosa Simplex With Mottled Pigmentation | Encephalopathy, Ethylmalonic | D-2-Hydroxyglutaric Aciduria | Centronuclear Myopathy | Infantile Nephropathic Cystinosis | Opisthorchiasis | Neuromuscular Disorders | Hyperparathyroidism, Secondary | Distal Spinal Muscular Atrophy | Persistent Truncus Arteriosus | Bulimia Nervosa | Fowler's Syndrome | Gitelman Syndrome | Treacher Collins Syndrome | Spondyloepimetaphyseal Dysplasia With Joint Laxity, Type 3 | Citrullinemia | Cutaneous Mastocytosis | Pneumonia, Bacterial | X-linked Charcot-Marie-Tooth Disease | Micropenis | Pancreatitis, Chronic | Heart Failure | Anthrax | Carbamoyl Phosphate Synthetase I Deficiency | Leukemia-lymphoma, Adult T-cell | Sepiapterin Reductase Deficiency | Adenoma, Pituitary | Brooke-Spiegler Syndrome | Spinocerebellar Ataxia Type 8 | Jaundice, Obstructive | Spinocerebellar Ataxia Type 16 | Erysipelas | Traboulsi Syndrome | Meningococcal Infections | Paroxysmal Kinesigenic Dyskinesia | Pontocerebellar Hypoplasia | Peritonitis | Delirium | Spondyloarthritis | Autoimmune Hemolytic Anemia | Gangliosidosis, GM1 | Porphyria, Variegate | Essential Fructosuria | Familial Episodic Pain Syndrome | Vici Syndrome | Anxiety Disorders | Infantile Spasm | Bleeding Disorder Due To CalDAG-GEFI Deficiency | Liebenberg Syndrome | Stromal Corneal Dystrophy | Norrie Disease | Lateral Meningocele Syndrome | Gangliosidosis | Non-proliferative Diabetic Retinopathy | Spinocerebellar Ataxia Type 10 | Multiple Sclerosis | Multicentric Carpotarsal Osteolysis Syndrome | Learning Disability | PHARC Syndrome | Ulcerative Colitis | Chromosome 5q Deletion Syndrome | Gaucher Disease | Sponastrime Dysplasia | Chanarin-Dorfman Syndrome | Fucosidosis | Glycogen Storage Disease Type 0 | Hepatitis A | Noonan Syndrome | Galloway-Mowat Syndrome | Duane Retraction Syndrome | Paternal Uniparental Disomy Of Chromosome 14 | Epidermolytic Palmoplantar Keratoderma | Oculocutaneous Albinism Type 1 | Wiskott-Aldrich Syndrome | Sitosterolemia | Fundus Albipunctatus | Ghosal Syndrome | Cartilage Disorders | Neurogenic Bladder | Congenital Muscular Dystrophy | Hemochromatosis Type 2 | Inborn Errors Of Metabolism | Amenorrhea | Kaposiform Hemangioendothelioma | Spinal Muscular Atrophy Type 2 | Inflammatory Joint Disease | Hyperlipidemia Type V | Hypophosphatemic Rickets, Autosomal Recessive, 1 | Blepharoconjunctivitis | Usher Syndrome | Keratoconjunctivitis | Microcephaly, Seizures, And Developmental Delay | Charcot-Marie-Tooth Disease Type 2D | Gastritis, Atrophic | Leber Congenital Amaurosis | Measles | Schwannoma | Multiple System Atrophy | Creatine Deficiency Syndrome | Allergic Contact Dermatitis | Eccrine Porocarcinoma | Lafora Disease | Non-small Cell Lung Cancer | Medium-chain Acyl-CoA Dehydrogenase Deficiency | Dominant Optic Atrophy | Sleep Apnea | Neutropenia | Microphthalmia | Osteoporosis-pseudoglioma Syndrome | Hereditary Mixed Polyposis Syndrome | Milk Allergy | Glutaric Aciduria Type 1 | Fraser Syndrome | CREST Syndrome | Gallstones | Intestinal Tuberculosis | Blepharo-cheilo-odontic Syndrome | Thrombocytopenia | Tracheal Disorders | Inflammatory Bowel Disease | Familial Retinal Arterial Macroaneurysm | Presbyopia | Pyruvate Dehydrogenase Deficiency | Cornelia De Lange Syndrome | Colorectal Adenoma | Hydrocephalus, Normal Pressure | Motor Neuron Diseases | Diffuse Intrinsic Pontine Glioma | Antisynthetase Syndrome | Sick Sinus Syndrome | Hydrops Fetalis | Mast Cell Leukemia | Neurocysticercosis | Carotid Artery Disease | Angiosarcoma | Diverticulitis | Pseudoachondroplasia | Thyroiditis | Chordoid Glioma | Uremic Pruritus | Lattice Corneal Dystrophy | Sarcoidosis | Nail-Patella Syndrome | Mitochondrial Cytopathy | Hyperuricemia | Membranous Nephropathy | Cysticercosis | Arterial Tortuosity Syndrome | Hemolytic Anemia | Glaucoma, Congenital | Hepatitis B, Chronic | Hereditary Elliptocytosis | Temtamy Preaxial Brachydactyly Syndrome | Ligneous Conjunctivitis | Myocardial Infarction | Thrombotic Microangiopathy | Acral Lentiginous Melanoma | Colitis, Collagenous | MELAS Syndrome | Meniere's Disease | Cryptorchidism | Growth Hormone Excess | Multiple Sclerosis, Primary Progressive | Stiff-man Syndrome | Neurofibroma, Plexiform | Myelomeningocele | Nemaline Myopathy 10 | Familial Partial Lipodystrophy | Melanoma, Uveal | Encephalocele | Acromesomelic Dysplasia | Hereditary Pyropoikilocytosis | Hyperbilirubinemia, Neonatal | Narcolepsy | Osteonecrosis | Pelvic Inflammatory Disease | Zimmermann-Laband Syndrome | Lymphoma | Acute Anterior Uveitis | Rett Syndrome | Infertility, Male | Cyst | Usher Syndrome Type I | Lymphangiomatosis | Pathological Gambling | Stroke | Hypokalemia | Pre-eclampsia | Dyggve-Melchior-Clausen Disease | Combined Deficiency Of Factor V And Factor VIII | Optic Neuropathy | Granular Corneal Dystrophy Type 1 | Hypercalcemia | Schaaf-Yang Syndrome | Carcinoid Tumor | Hyperthermia, Malignant | Nijmegen Breakage Syndrome | TARP Syndrome | Dyslipidemia | Encephalopathy | Hypervalinemia | Congenital Dyserythropoietic Anemia | Congenital Generalized Lipodystrophy | Osteogenesis Imperfecta Type II | Atopic Dermatitis | Amyloidosis | Silicosis | Congenital Disorders Of Glycosylation | Odonto-onycho-dermal Dysplasia | Precocious Puberty | Kabuki Syndrome 2 | Avian Influenza | Leri-Weill Dyschondrosteosis | Multiple Sulfatase Deficiency | Hepatitis | Chronic Beryllium Disease | Lymphedema | Hypobetalipoproteinemias | Metaphyseal Chondrodysplasia, Schmid Type | Vitreoretinopathy, Proliferative | Bartter Syndrome | Fatty Aldehyde Dehydrogenase Deficiency | Encephalopathy, Glycine | Corneal Ulcer | Trichotillomania | Phosphoglycerate Dehydrogenase Deficiency | Hemochromatosis | Multiple Hamartoma Syndrome | Nephritis, Interstitial | Perivascular Epithelioid Cell Tumor | Communication Disorders | Spinocerebellar Ataxia Type 17 | Pitt-Hopkins Syndrome | Non-Hodgkin Lymphoma | Trichothiodystrophy | Anodontia | Mohr-Tranebjaerg Syndrome | GNE Myopathy | Follicular Dendritic Cell Sarcoma | Viral Meningitis | Imerslund-Grasbeck Syndrome | Maternally Inherited Diabetes And Deafness | Infantile Refsum Disease | Endometrial Hyperplasia | Apparent Mineralocorticoid Excess Syndrome | Primary Aldosteronism | Postpoliomyelitis Syndrome | Progressive External Ophthalmoplegia | Fibronectin Glomerulopathy | Amyotrophic Lateral Sclerosis-parkinsonism-dementia Complex | Lesch-Nyhan Syndrome | Alopecia Areata | Leiomyosarcoma | Paget's Disease Of The Breast | Glycogen Storage Disease Type 9 | Focal Segmental Glomerulosclerosis | Holoprosencephaly | Tinea Versicolor | Pemphigoid | Osteogenesis Imperfecta Type V | Hereditary Spastic Paraplegia | Mannosidase Deficiency Diseases | Cerebellofaciodental Syndrome | Keratitis | Spinocerebellar Ataxia Type 14 | Gingivitis | Rash | Hemimegalencephaly | Stickler Syndrome | Hemorrhoids | Cancer, Prostate | Carcinoid Syndrome | Hypophosphatemic Rickets With Hypercalciuria, Hereditary | Basal Ganglia Disease, Biotin-responsive | Primary Ovarian Insufficiency | Coronary Heart Disease | Retinitis Pigmentosa | Craniofrontonasal Syndrome | Cohen Syndrome | Retinopathy, Diabetic | Cardiomyopathy, Peripartum | Dengue Shock Syndrome | Malaria | Cholesteryl Ester Storage Disease | Hemoglobinopathies | Bronchitis, Chronic | Primrose Syndrome | Hypertension, Essential | Aceruloplasminemia | Mabry Syndrome | Heart Block | Coffin-Lowry Syndrome | Kabuki Syndrome | Smith-Kingsmore Syndrome | Irritable Bowel Syndrome | Myoclonus-dystonia Syndrome | Splenomegaly | Lung Diseases | Leukoplakia, Oral | Danon Disease | Dyslexia | Cirrhosis | Hemosiderosis | Chorioretinitis | Congenital Disorders Of Glycosylation Type II | Carcinoma In Situ | Polymyalgia Rheumatica | Neonatal Progeroid Syndrome | Coronary Artery Disease | Pyloric Stenosis, Infantile Hypertrophic | Hairy Cell Leukemia | Congenital Sodium Diarrhea | Polymicrogyria | Neuromyotonia | Choroiditis | Asperger Syndrome | Dermatitis | Sarcosinemia | Thromboembolism | Swine Influenza | Adenosine Deaminase Deficiency | Juvenile Polyposis | Autoimmune Interstitial Lung, Joint, And Kidney Disease | Glycogen Storage Disease Type 3 | 3-hydroxyacyl-CoA Dehydrogenase Deficiency | Chordoma | Diabetic Macular Edema | Myosin Storage Myopathy | Hoyeraal-Hreidarsson Syndrome | Strabismus | Hyperparathyroidism | Multiple Sclerosis, Secondary Progressive | Goldenhar Syndrome | Polyarteritis Nodosa | Antiphospholipid Syndrome | Bare Lymphocyte Syndrome | Infertility | Thyroid Dyshormonogenesis | Macular Degeneration | Paraplegia | Cerebral Amyloid Angiopathy | Infectious Diarrhea | Malnutrition | Meningioma, Benign | Immunoproliferative Disorders | Hyperinsulinemia | Ophthalmia, Sympathetic | Achondrogenesis | Gastroenteritis | Cryopyrin-associated Periodic Syndromes | Mucolipidosis Type II | ACTH-independent Macronodular Adrenal Hyperplasia | Waardenburg Syndrome | Gastroenteritis, Eosinophilic | Charcot-Marie-Tooth Disease, Type 1A | Glutathione Synthetase Deficiency | Lyme Disease | Brenner Tumor | Apraxia | Hereditary Multiple Exostoses | Sertoli Cell-only Syndrome | Congenital Fiber-type Disproportion Myopathy | Intestinal Hypomagnesemia 1 | Cryptococcal Meningitis | Split Hand-foot Malformation | Atelosteogenesis Type 1