Hartnup Disease

About the Disease
Hartnup Disorder, also known as hartnup disease, is related to aminoaciduria and cystinuria, and has symptoms including seizures An important gene associated with Hartnup Disorder is SLC6A19 (Solute Carrier Family 6 Member 19), and among its related pathways/superpathways are Disease and Transport of inorganic cations/anions and amino acids/oligopeptides. Affiliated tissues include Kidney, skin and cerebellum, and related phenotypes are hyperreflexia and eeg abnormality

Common Targets
SLC6A19

Note: If you'd like to get a target analysis report for Hartnup Disease, or if you are interested to learn how our AI-powered BDE-Chem can design therapeutic molecules to interact with the target(s) above against the disease of Hartnup Disease at a cost 90% lower than traditional approaches, please feel free to contact us at BD@silexon.ai.

Other Diseases

Coffin-Siris Syndrome | Adult Polyglucosan Body Disease | Chloridorrhea, Congenital | X-linked Myotubular Myopathy | Mitochondrial DNA Depletion Syndrome, Hepatocerebral Form | Familial Thoracic Aortic Aneurysm | Diabetic Encephalopathy | Fundus Albipunctatus | Neuroectodermal Tumors, Primitive | Hypothyroidism | Craniolenticulosutural Dysplasia | Postpartum Depression | Toxoplasmosis | Lymphangiomatosis | Imerslund-Grasbeck Syndrome | Pseudohypoparathyroidism Type 1A | Orthostatic Intolerance | Whipple's Disease | Presbyopia | Sclerosteosis | Pterygium | Kearns-Sayre Syndrome | Epilepsy | Hereditary Xerocytosis | Osteogenesis Imperfecta Type IV | Williams Syndrome | Inflammatory Joint Disease | Scleroderma, Diffuse | Myofibromatosis | Spitz Nevus | Light Chain Amyloidosis | Paracoccidioidomycosis | Palsy, Cerebral | Gastroenteritis, Eosinophilic | Martsolf Syndrome | Protein S Deficiency | Methemoglobinemia | Spinocerebellar Ataxia Type 40 | Keratopathy | Nephrosclerosis | Nanophthalmos | Hypohidrotic Ectodermal Dysplasia | Takenouchi-Kosaki Syndrome | IMAGe Syndrome | Congenital Bilateral Absence Of Vas Deferens | Goiter, Nodular | Lichen Planus | Neuronal Ceroid Lipofuscinosis | Pneumococcal Meningitis | Coenzyme Q10 Deficiency | Spinocerebellar Ataxia Type 5 | Meningeal Melanocytoma | Isovaleric Acidemia | Infantile Liver Failure Syndrome 1 | Hypertension, Renal | GATA2 Deficiency | Beare-Stevenson Syndrome | Spastic Paraplegia Type 7 | Anterior Segment Dysgenesis | Enhanced S-cone Syndrome | Pericarditis | Ataxia-ocular Apraxia 2 | Synovitis | Diverticulitis | Aceruloplasminemia | Hemorrhagic Disorders | Prurigo Nodularis | Gaucher Disease | Polycythemia | Pitt-Hopkins Syndrome | Schizoaffective Disorder | Hypersomnia | Maple Syrup Urine Disease | Tinea | Bloom Syndrome | Oligodendroglioma | Geleophysic Dysplasia | Acute Myeloid Leukemia | Pendred Syndrome | Non-small Cell Lung Cancer | Tyrosinemia | Polycystic Liver | Congenital Hemolytic Anemia | Glomerulonephritis | Hemorrhage | Pseudomyxoma Peritonei | C3 Glomerulopathy | Hereditary Pyropoikilocytosis | Superficial Spreading Melanoma | Stuve-Wiedemann Syndrome | Acute Lung Injury | Myelitis | Aldosteronism | Mevalonate Kinase Deficiency | Reticular Dysgenesis | Diabetes Mellitus, Transient Neonatal | Ligneous Conjunctivitis | Amenorrhea | Succinic Semialdehyde Dehydrogenase Deficiency | Limb Girdle Muscular Dystrophy | Autoimmune Polyendocrinopathy Syndrome Type I | Sarcoma, Alveolar Soft Part | Renal Tubular Acidosis | Glycogen Storage Disease Type 1b | Waldenstrom Macroglobulinemia | Amyloidosis | Early Infantile Epileptic Encephalopathy 28 | DRESS Syndrome | Colitis, Collagenous | Spinal Muscular Atrophy Type 3 | Leukodystrophies | Frontometaphyseal Dysplasia | Hyperinsulinemic Hypoglycemia | Protein C Deficiency | Dent Disease | Open-angle Glaucoma | Cholangiocarcinoma | Ganglioglioma | Autosomal Recessive Spastic Paraplegia Type 54 | Cysticercosis | Granular Corneal Dystrophy Type 1 | Erectile Dysfunction | Carney Triad | Familial Advanced Sleep Phase Syndrome | Chorioretinitis | Hidradenitis | Congenital Hypofibrinogenemia | Megacystis-microcolon-intestinal Hypoperistalsis Syndrome | Porphyria, Acute Intermittent | Milk Allergy | Pregnancy, Ectopic | Hypertriglyceridemia | Kabuki Syndrome 2 | Agnathia-Otocephaly Complex | Ichthyosis Hystrix, Curth-Macklin Type | Hereditary Hemorrhagic Telangiectasia Type 2 | Glycogen Storage Disease Type 4 | Creatine Deficiency Syndrome Due To AGAT Deficiency | Epidermolysis Bullosa Dystrophica | Chediak-Higashi Syndrome | Crimean-Congo Hemorrhagic Fever | Aplastic Anemia | Salla Disease | L-2-Hydroxyglutaric Aciduria | Creatine Deficiency Syndrome | Angina Pectoris | Vasculitis | Primary Aldosteronism | Hemochromatosis | Phenylketonuria | Low Tension Glaucoma | Galactosialidosis | Mastitis | Optic Atrophy 2 | Schindler Disease | Onchocerciasis | Pontocerebellar Hypoplasia Type 2 | Granuloma Annulare | Ornithine Transcarbamylase Deficiency | Pneumonia, Mycoplasma | Duchenne Muscular Dystrophy | Endometritis | Focal Facial Dermal Dysplasia | Von Hippel-Lindau Disease | Mandibuloacral Dysplasia With Type A Lipodystrophy | Spinocerebellar Ataxia Type 27 | Acrodysostosis | Hypolipoproteinemia | Hepatitis, Alcoholic | MELAS Syndrome | Gastroenteritis | Van Der Knaap Disease | Gestational Trophoblastic Disease | Thin Basement Membrane Disease | Diarrhea | Brooke-Spiegler Syndrome | Osteoarthritis | Rolandic Epilepsy | Colon Adenoma | Hyperoxaluria | Deafness, Dystonia, And Cerebral Hypomyelination | Scapuloperoneal Myopathy, X-linked Dominant | Paraganglioma | Menkes Disease | Rothmund-Thomson Syndrome | Autonomic Neuropathy | Spinal Muscular Atrophy Type 2 | Astrocytoma | Renal Failure | Ocular Surface Squamous Neoplasia | Cancer, Lung | Gangliosidosis, GM1 | Migraine | Spasticity | Alkaptonuria | Schnyder Crystalline Corneal Dystrophy | Craniofrontonasal Syndrome | Glaucoma | McCune-Albright Syndrome | Gaze Palsy, Familial Horizontal, With Progressive Scoliosis, 2 | Acute Tubular Necrosis | Leukocyte Adhesion Deficiency Type 1 | Rhizomelic Chondrodysplasia Punctata | Emery-Dreifuss Muscular Dystrophy | Osteoglophonic Dysplasia | Hemolytic Uremic Syndrome | Mitochondrial Disease | Primary Ovarian Insufficiency | Chondrodysplasia Punctata 2, X-linked Dominant | Arthritis, Psoriatic | Adenylosuccinate Lyase Deficiency | Cluster Headache | Chronic Myeloid Leukemia | Fraser Syndrome | Nance-Horan Syndrome | Neurodegeneration With Brain Iron Accumulation | Congenital Adrenal Hyperplasia | Gray Platelet Syndrome | Hennekam Lymphangiectasia-lymphedema Syndrome | Facioscapulohumeral Muscular Dystrophy Type 1 | Oligospermia | Common Variable Immunodeficiency | Congenital Fiber-type Disproportion Myopathy | Hypoplastic Left Heart Syndrome | Porphyria, Variegate | Sleep Disorder | Nemaline Myopathy | Anorectal Malformations | Central Core Disease | TARP Syndrome | Fetal And Neonatal Alloimmune Thrombocytopenia | Glioma | Myelofibrosis | Basal Ganglia Disease | Insulinoma | Steel Syndrome | Alveolar Capillary Dysplasia | Esophagitis, Eosinophilic | Autoimmune Hemolytic Anemia | Fuchs Heterochromic Iridocyclitis | Renal Hypouricemia | Polycystic Kidney, Autosomal Recessive | Recurrent Respiratory Papillomatosis | Asplenia | Twin-to-twin Transfusion Syndrome | Uveitis, Anterior | Schwannomatosis | Withdrawal Syndrome | Gerodermia Osteodysplastica | Senior-Loken Syndrome | Shwachman-Bodian-Diamond Syndrome | Hereditary Neuropathy With Liability To Pressure Palsies | Chanarin-Dorfman Syndrome | Anencephaly | IgA Deficiency | Focal Dermal Hypoplasia | Eclampsia | Left Ventricular Noncompaction | Opisthorchiasis | Blepharo-cheilo-odontic Syndrome | Progressive Familial Intrahepatic Cholestasis | Hyperbilirubinemia, Neonatal | Neuroblastoma | Swine Influenza | Palmoplantar Keratoderma | Spitzoid Melanoma | Polycythemia Vera | Histiocytic Sarcoma | Pyruvate Carboxylase Deficiency Disease | Angiomyolipoma | Blepharitis | Small Lymphocytic Lymphoma | VEXAS Syndrome | Familial Hypertrophic Cardiomyopathy | Microphthalmia | Bone Giant Cell Tumor | Primary Familial Brain Calcification | Central Retinal Artery Occlusion | Wiedemann-Steiner Syndrome | Poirier-Bienvenu Neurodevelopmental Syndrome | POEMS Syndrome | Spinal Muscular Atrophy | Frontotemporal Dementia | Sjogren Syndrome | Trichotillomania | Kawasaki Disease | Arthritis, Gouty | CDKL5 Deficiency Disorder | Behcet's Disease | Coffin-Lowry Syndrome | Ureteropelvic Junction Obstruction | Epidermolytic Palmoplantar Keratoderma | Neurofibromatosis Type 1 | Danon Disease | Hypocalcemia | Multifocal Motor Neuropathy | Long QT Syndrome Type 1 | Miyoshi Myopathy | Progressive Familial Intrahepatic Cholestasis Type 2 | Craniometaphyseal Dysplasia | Wilson's Disease | Angioedema | Pulmonary Stenosis | Empyema | Osteosarcoma | Paroxysmal Kinesigenic Dyskinesia | Cholestasis | Beckwith-Wiedemann Syndrome | Niemann-Pick Disease, Type A | Mannosidase Deficiency Diseases | CHARGE Syndrome | Congenital Dyserythropoietic Anemia Type 1 | Systemic Mastocytosis | Spinocerebellar Ataxia Type 1 | Dupuytren Disease | Adrenomyeloneuropathy | Hepatitis C, Chronic | DICER1 Syndrome | Cardiospondylocarpofacial Syndrome | Androgenic Alopecia | Autism | Kabuki Syndrome | Familial Male-limited Precocious Puberty | Renal-hepatic-pancreatic Dysplasia | Esophageal Adenocarcinoma | Ataxia-hypogonadism-choroidal Dystrophy Syndrome | Keratosis, Seborrheic | HANAC Syndrome | Tuberculous Meningitis | Fibronectin Glomerulopathy | Zygomycosis | Hepatitis, Chronic | Adenosine Deaminase Deficiency | Chorea-acanthocytosis | Hypopigmentation | Hereditary Spherocytosis | Eosinophilia | Oculopharyngeal Muscular Dystrophy | Malaria | Rhabdoid Tumor | Anorexia Nervosa | ACTH-independent Macronodular Adrenal Hyperplasia | Eccrine Porocarcinoma | Autism Spectrum Disorders | Lipodystrophy | Motion Sickness | Familial Pheochromocytoma-paraganglioma | Vulvovaginitis | Heart Block | Glucagonoma | Inflammatory Linear Verrucous Epidermal Nevus | Anorchia | Tracheal Disorders | Papilloma | PHARC Syndrome | Early Infantile Epileptic Encephalopathy 4 | Angioedema, Hereditary | Neurocutaneous Syndromes | Scleritis | Cataract | Lactose Intolerance | Pfeiffer Syndrome | Mesothelioma, Malignant | Achromatopsia | Glomerulonephritis, Membranoproliferative | Infectious Diarrhea | Cutis Laxa | Melanocytic Nevus | Teratozoospermia | Acute Lymphocytic Leukemia | Pancreatitis | Wolfram Syndrome 2 | Hereditary Multiple Exostoses | Neurodevelopmental Disorder With Central Hypotonia And Dysmorphic Facies | Cheilitis | Renal Medullary Carcinoma | Cerebrotendinous Xanthomatosis | Short-chain Acyl-CoA Dehydrogenase Deficiency | Jacobsen Syndrome | Lymphoproliferative Disease, X-linked | Ichthyosis, X-linked | Neurocutaneous Melanocytosis | Fascioliasis | Celiac Disease | Pleural Tuberculosis | Spinocerebellar Ataxia Type 20 | Kaposi Sarcoma | Hyperparathyroidism, Primary | Hartsfield Syndrome | Low Phospholipid Associated Cholelithiasis | Rash | Diastrophic Dysplasia | Blastoma, Pleuropulmonary | Anti-NMDA Receptor Encephalitis | Down Syndrome | Tietze Syndrome | Gingivitis | Charcot-Marie-Tooth Disease Type 4E | Chronic Idiopathic Myelofibrosis | Hypervalinemia