Withdrawal Syndrome

About the Disease
Withdrawal Disorder, also known as withdrawal syndrome, is related to neonatal abstinence syndrome and alcohol use disorder, and has symptoms including seizures, drug withdrawal symptoms and withdrawal symptoms. An important gene associated with Withdrawal Disorder is OPRM1 (Opioid Receptor Mu 1), and among its related pathways/superpathways are GPCR downstream signalling and Signal Transduction. The drugs Acetylcholine and Lofexidine have been mentioned in the context of this disorder. Affiliated tissues include brain, liver and cortex, and related phenotypes are homeostasis/metabolism and nervous system

Common Targets
MGLL | SLC6A4 | HTR2A | CHRNA7 | GRM2 | Nicotinic alpha4beta2 receptor | HTR2C | MAOB | HTR3B | CHRNA4 | HTR1A | SLC18A2 | HTR3A | Gamma-Aminobutyric acid type B receptor

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