Disease

Lentigo

About the Disease
Lentigines, also known as lentigo, is related to noonan syndrome with multiple lentigines and hyperpigmentation with or without hypopigmentation, familial progressive. An important gene associated with Lentigines is PRKAR1A (Protein Kinase CAMP-Dependent Type I Regulatory Subunit Alpha), and among its related pathways/superpathways are Disease and Signal Transduction. The drugs Aminolevulinic acid and Glycolic acid have been mentioned in the context of this disorder. Affiliated tissues include skin, pituitary and heart, and related phenotypes are nystagmus and abnormality of the skin

Common Targets
SASH1 | VHL | CRBN | KIT | G673 | WNT1

疾病靶点研报
Lentigo

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