Hereditary Neuropathy With Liability To Pressure Palsies

About the Disease
Neuropathy, Hereditary, with Liability to Pressure Palsies, also known as hereditary neuropathy with liability to pressure palsies, is related to charcot-marie-tooth disease type 1g and charcot-marie-tooth disease, axonal, type 2a1, and has symptoms including neuralgia An important gene associated with Neuropathy, Hereditary, with Liability to Pressure Palsies is PMP22 (Peripheral Myelin Protein 22), and among its related pathways/superpathways are Neural crest differentiation and Intracellular trafficking proteins involved in CMT neuropathy. The drugs Folic acid and Lipoic acid have been mentioned in the context of this disorder. Affiliated tissues include spinal cord, brain and dorsal root ganglion, and related phenotypes are peripheral neuropathy and decreased motor nerve conduction velocity

Common Targets
PMP22 | Potassium Channels (nonspecified subtype) | INF2 | SH3TC2

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