Nail-Patella Syndrome

About the Disease
Nail-Patella Syndrome, also known as turner-kieser syndrome, is related to ehlers-danlos syndrome, classic type, 2 and membranous nephropathy, and has symptoms including arthralgia, metatarsalgia and koilonychia. An important gene associated with Nail-Patella Syndrome is LMX1B (LIM Homeobox Transcription Factor 1 Beta), and among its related pathways/superpathways are Phospholipase-C Pathway and Cell junction organization. Affiliated tissues include bone, eye and kidney, and related phenotypes are constipation and arthritis

Common Targets
TBX4 | KANK1 | LMX1B | SOX9 | CUBN

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