Adenosine Deaminase 2 Deficiency

About the Disease
Vasculitis, Autoinflammation, Immunodeficiency, and Hematologic Defects Syndrome, also known as vasculitis due to ada2 deficiency, is related to cutaneous polyarteritis nodosa and sneddon syndrome, and has symptoms including headache, hemiplegia and seizures. An important gene associated with Vasculitis, Autoinflammation, Immunodeficiency, and Hematologic Defects Syndrome is ADA2 (Adenosine Deaminase 2). The drugs Azathioprine and Cyclophosphamide have been mentioned in the context of this disorder. Affiliated tissues include skin, liver and spleen, and related phenotypes are anemia and hypertension

Common Targets
ADA2

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