Von Hippel-Lindau Disease

About the Disease
Von Hippel-Lindau Syndrome, also known as von hippel-lindau disease, is related to hemangioblastoma and pancreatic serous cystadenoma, and has symptoms including tinnitus and vertigo. An important gene associated with Von Hippel-Lindau Syndrome is VHL (Von Hippel-Lindau Tumor Suppressor), and among its related pathways/superpathways are Signal Transduction and Malignant pleural mesothelioma. The drugs Ranibizumab and Somatostatin have been mentioned in the context of this disorder. Affiliated tissues include spinal cord, pancreas and kidney, and related phenotypes are hypertension and renal cell carcinoma

Common Targets
FGFR1 | FLT1 | FLT4 | KDR | CFD | ELOC | HSP90AB1 | FLT3 | RET | KIT | VHL | beta-Adrenoceptor (nonspecified subtype) | Complement Complex | Platelet-Derived Growth Factor (PDGF) (nonspecified subtype) | SLC2A1 | Vascular endothelial growth factors (VEGF) (nonspecified subtype) | NAMPT | ABL1 | HIF1A | PDGFRB | CSF1R | EPAS1 | G1956 | FGFR3 | G3320

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