Stiff-man Syndrome

About the Disease
Stiff-Person Syndrome, also known as stiff-man syndrome, is related to hyperekplexia 1 and conversion disorder, and has symptoms including fever, muscle rigidity and opisthotonus. An important gene associated with Stiff-Person Syndrome is AMPH (Amphiphysin), and among its related pathways/superpathways are Neuroscience and Glucose / Energy Metabolism. The drugs Prednisone and Cytarabine have been mentioned in the context of this disorder. Affiliated tissues include spinal cord, brain and bone, and related phenotypes are hyperhidrosis and anxiety

Common Targets
IL2

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