Intracranial Hypertension

About the Disease
Intracranial Hypertension, also known as raised intracranial pressure, is related to cerebral sinovenous thrombosis and headache, and has symptoms including headache, vomiting and altered mental status. An important gene associated with Intracranial Hypertension is AQP4 (Aquaporin 4), and among its related pathways/superpathways are Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) and Neuroinflammation and glutamatergic signaling. The drugs Minocycline and Lymecycline have been mentioned in the context of this disorder. Affiliated tissues include brain, liver and eye, and related phenotypes are no effect and no effect

Common Targets
CA1 | AQP4 | ACHE | AQP4-AS1 | HSD11B1 | G3630 | CA2 | HTR2C | GLP1R

Note: If you'd like to get a target analysis report for Intracranial Hypertension, or if you are interested to learn how our AI-powered BDE-Chem can design therapeutic molecules to interact with the target(s) above against the disease of Intracranial Hypertension at a cost 90% lower than traditional approaches, please feel free to contact us at BD@silexon.ai.

Other Diseases

Ventricular Septal Defect | Pulmonary Vein Stenosis | Macrodactyly | Autoimmune Polyendocrinopathy Syndrome Type I | Viral Meningitis | Cranioectodermal Dysplasia | LRBA Deficiency | Polymicrogyria | Splenomegaly | Moyamoya Disease | Presbycusis | Multicentric Carpotarsal Osteolysis Syndrome | Galactosemia | Bartter Syndrome | Hypopigmentation | Infertility, Male | Arteriovenous Malformations | Hereditary Neuropathy With Liability To Pressure Palsies | Hemorrhagic Disorders | Progressive Familial Intrahepatic Cholestasis Type 2 | Cat Eye Syndrome | Spinocerebellar Ataxia Type 38 | Myelodysplasia | Ligneous Conjunctivitis | Becker Muscular Dystrophy | Leishmaniasis, Visceral | Sclerosing Cholangitis | Pleural Tuberculosis | Vitamin A Deficiency | Chylothorax, Congenital | Optic Atrophy 2 | Gliosarcoma | Lymphoma, Primary Cutaneous Anaplastic Large Cell | Juvenile Polyposis | Prolidase Deficiency | Polycythemia Vera | Vogt-Koyanagi-Harada Syndrome | Stroke | Waardenburg Syndrome Type 4A | Anorectal Malformations | Myoclonus | Multifocal Motor Neuropathy | Benign Familial Infantile Seizures | Larsen Syndrome | Intracranial Hypertension | Nemaline Myopathy 8 | Brenner Tumor | SAPHO Syndrome | Autosomal Recessive Bestrophinopathy | Cancer, Lung | Non-small Cell Lung Cancer | Albinism | Intestinal Pseudo-obstruction | Neutrophilia | Gastritis | Blue Nevus | Citrullinemia | Congenital Disorders Of Glycosylation Type II | Leukoplakia, Oral | Agnathia-Otocephaly Complex | Klinefelter Syndrome | Erythema Nodosum | Sialidosis | Arthrogryposis | Aromatic L-amino Acid Decarboxylase Deficiency | Renal Dysplasia | Pseudo-pseudohypoparathyroidism | Scabies | Pain | Smith-Magenis Syndrome | Aplastic Anemia | Cleidocranial Dysplasia | Periventricular Leukomalacia | Pseudoachondroplasia | Primary Cutaneous Amyloidosis | Eating Disorder | Polycystic Liver | Uterine Leiomyoma | Urea Cycle Disorder | Familial Mediterranean Fever | Spinocerebellar Ataxia Type 42 | Infertility | Sarcoma | Venous Insufficiency | Influenza | Intestinal Obstruction | Alexander Disease | Blepharospasm | Hemophagocytic Lymphohistiocytosis | Arrhythmogenic Right Ventricular Cardiomyopathy | Mountain Sickness | Narcolepsy | Eosinophilia | Distal Myopathy 2 | Platyspondylic Lethal Skeletal Dysplasia, Torrance Type | Celiac Disease | Periodic Limb Movement Disorder | Thrombocythemia, Essential | Meningococcal Infections | Metachromatic Leukodystrophy | Keratosis, Seborrheic | Chronic Enteropathy Associated With SLCO2A1 Gene | Aicardi-Goutieres Syndrome | Congenital Sodium Diarrhea | Hypertension, Pulmonary | Thyroid Dyshormonogenesis | Hypogammaglobulinemia | Waardenburg Syndrome Type 2A | Speech Disorders | Cataplexy | Fukuyama Congenital Muscular Dystrophy | Glomerulonephritis | Pituitary Stalk Interruption Syndrome | Pontocerebellar Hypoplasia | Epidermolysis Bullosa | Schamberg Disease | Chondrodysplasia Punctata 1, X-linked Recessive | Distal Spinal Muscular Atrophy | Neurofibromatosis Type 1 | Whipple's Disease | CREST Syndrome | Dyslipidemia | Non-Langerhans Cell Histiocytosis | Metaphyseal Chondrodysplasia, Schmid Type | Hereditary Folate Malabsorption | Distal Myopathy | Neuroendocrine Cancer | Dystonia-parkinsonism, X-linked | Pericarditis | Epicondylitis | Hypohidrotic Ectodermal Dysplasia | Chronic Granulomatous Disease, X-linked | Headache | Diabetes Insipidus, Neurogenic | Spinocerebellar Ataxia Type 3 | Diabetic Macular Edema | Delirium | Encephalitis, Tick-borne | Renal Hypouricemia | Neurocutaneous Syndromes | Myositis | Dysequilibrium Syndrome | Tracheal Disorders | Persistent Hyperplastic Primary Vitreous | Cerebral Amyloid Angiopathy | D-2-Hydroxyglutaric Aciduria | Okihiro Syndrome | Cornelia De Lange Syndrome | Charcot-Marie-Tooth Disease, Type 2 | Postpoliomyelitis Syndrome | Arterial Tortuosity Syndrome | Bursitis | Metabolic Syndrome | Fascioliasis | Endometritis | Nephrosclerosis | Vitiligo | Open-angle Glaucoma | HIBCH Deficiency | Spinocerebellar Ataxia Type 12 | Cholangiocarcinoma | Fanconi Syndrome | Wolff-Parkinson-White Syndrome | Adenoma, Pituitary | L-2-Hydroxyglutaric Aciduria | Dermatitis | Hepatopulmonary Syndrome | Bacterial Meningitis | Progressive Osseous Heteroplasia | Peripheral Neuropathy | Rosacea | Fucosidosis | Congestive Heart Failure | Cryptococcal Meningitis | Craniofacial Dysostosis | Lung Diseases | Megaloblastic Anemia | Central Retinal Artery Occlusion | Knobloch Syndrome | Spinocerebellar Ataxia Type 31 | CDKL5 Deficiency Disorder | Hereditary Coproporphyria | Hydrocephalus | Spondylometaphyseal Dysplasia | Mitochondrial DNA Depletion Syndrome 13 | MELAS Syndrome | Epithelioid Hemangioma | Tibial Muscular Dystrophy | Pseudohypoaldosteronism | Milk Allergy | Familial Male-limited Precocious Puberty | Rift Valley Fever | Lattice Corneal Dystrophy Type 1 | Huntington's Disease | Anti-NMDA Receptor Encephalitis | Anterior Segment Dysgenesis | Dwarfism | Congenital Ichthyosiform Erythroderma | Tyrosine Hydroxylase Deficiency | Autoimmune Interstitial Lung, Joint, And Kidney Disease | Cardiac Arrest | Rett Syndrome | Basal Cell Nevus Syndrome | Acute Lymphocytic Leukemia | Osteogenesis Imperfecta Type I | Gardner Syndrome | Spondyloepiphyseal Dysplasia Tarda, X-linked | Glutaric Aciduria Type 3 | Glycogen Storage Disease Type 6 | Neuroectodermal Tumors, Primitive | Hypereosinophilic Syndrome | Hereditary Sensory And Autonomic Neuropathy | Postaxial Polydactyly | Inflammatory Myofibroblastic Tumor | Trichothiodystrophy | Nicolaides-Baraitser Syndrome | Blepharoconjunctivitis | Maternally Inherited Diabetes And Deafness | Malignant Peripheral Nerve Sheath Tumor | Hepatic Steatosis | Glanzmann Thrombasthenia | Arts Syndrome | Episodic Ataxia Type 1 | Immunoproliferative Disorders | Duane Retraction Syndrome | Sulfite Oxidase Deficiency | Fibrodysplasia Ossificans Progressiva | GLUT1 Deficiency Syndrome | Alkaptonuria | Superficial Spreading Melanoma | Primary Hyperoxaluria | Lattice Corneal Dystrophy | Adrenomyeloneuropathy | Split Hand-foot Malformation | Pulverulent Zonular Cataract | Goldenhar Syndrome | Hereditary Sensory Neuropathy Type 1 | Auriculocondylar Syndrome | Menkes Disease | Blepharitis | Hereditary Hemorrhagic Telangiectasia | Central Core Disease | Peutz-Jeghers Syndrome | Sertoli Cell-only Syndrome | Primary Sclerosing Cholangitis | Oculocutaneous Albinism Type 2 | Huntington's Disease-like 2 | VEXAS Syndrome | Hypospadias | Galactosialidosis | Nijmegen Breakage Syndrome | Benign Familial Neonatal Convulsions | Smoldering Myeloma | Creutzfeldt-Jakob Disease | Gnathodiaphyseal Dysplasia | Situs Inversus | Nemaline Myopathy | Cholangitis | Myelitis, Transverse | Epidermodysplasia Verruciformis | Hypermetropia | Hyperlipidemia Type V | Torticollis | Melanoma, Uveal | Pure Autonomic Failure | Encephalopathy, Ethylmalonic | Antithrombin III Deficiency | Colitis, Microscopic | Nevus | Diabetes | CHARGE Syndrome | Dowling-Degos Disease | Nestor-Guillermo Progeria Syndrome | DRESS Syndrome | Usher Syndrome Type I | Myosin Storage Myopathy | Congenital Central Hypoventilation Syndrome | Liver Failure, Acute Infantile | Mitochondrial Myopathy | Pernicious Anemia | Hyper IgE Syndrome | Autism | Learning Disability | Combined Pituitary Hormone Deficiency | Pulmonary Tuberculosis | Hypertrophic Osteoarthropathy, Primary, Autosomal Recessive 1 | Polyomavirus Nephropathy | Colon Adenoma | Hyperandrogenemia | Barakat Syndrome | Ectodermal Dysplasia | Asphyxia Neonatorum | Spinocerebellar Ataxia Type 28 | Pseudomyxoma Peritonei | KBG Syndrome | Congenital Primary Aphakia | Acute Leukemia | Sleep Apnea, Obstructive | Acanthosis Nigricans | Cabezas Syndrome | Aarskog-Scott Syndrome | Scleroderma, Diffuse | Angioedema | Megalencephaly | Autoimmune Hemolytic Anemia | Ehlers-Danlos Syndrome With Progressive Kyphoscoliosis, Myopathy, And Hearing Loss | Renpenning Syndrome | Cystitis | Reye Syndrome | Stickler Syndrome | Hypokalemia | Cancer, Breast | Persistent Truncus Arteriosus | Antenatal Bartter Syndrome Type 1 | Chiari Malformation Type I | Common Variable Immunodeficiency | Gangliosidosis, GM1 | Spinal Muscular Atrophy Type 2 | Primary Progressive Nonfluent Aphasia | Hartnup Disease | Tay-Sachs Disease | Patent Foramen Ovale | Wolman Disease | Prostatitis | Long QT Syndrome Type 2 | Fetal Alcohol Syndrome | Juvenile Myoclonic Epilepsy | DNA Ligase IV Deficiency | Sengers Syndrome | Achromatopsia | Pleomorphic Xanthoastrocytoma | Cerebrotendinous Xanthomatosis | Synpolydactyly | Scapuloperoneal Myopathy, X-linked Dominant | Hemosiderosis | Multiple System Atrophy | Agoraphobia | Bietti Crystalline Dystrophy | Chronic Lymphocytic Leukemia | Wiskott-Aldrich Syndrome | X-linked Charcot-Marie-Tooth Disease | Heterotaxy | Cousin Syndrome | Fibrillation, Atrial | Gigantism | Holoprosencephaly | Familial Exudative Vitreoretinopathy | Enhanced S-cone Syndrome | Schizencephaly | Spinocerebellar Ataxia Type 2 | Hydronephrosis | Sarcoma, Endometrial Stromal | Motor Neuron Diseases | Camptocormia | Diastrophic Dysplasia | Nasodigitoacoustic Syndrome | Rhabdomyosarcoma | Schistosomiasis | Pemphigus Foliaceus | Melanoma, Malignant | Chronic Neutrophilic Leukemia | Spinocerebellar Ataxia Type 21 | Retinopathy, Diabetic | Chudley-McCullough Syndrome | Peeling Skin Syndrome Type B | Adrenal Insufficiency | Focal Facial Dermal Dysplasia | Familial Hyperaldosteronism | Choriocarcinoma | Lymphoma, AIDS-related | Lyme Disease | Ichthyosis, X-linked | Epilepsy, Generalized | Trimethylaminuria | 3-methylglutaconic Aciduria Type I | Adult Polyglucosan Body Disease | Mannosidase Deficiency Diseases | Seborrheic Dermatitis | Hereditary Hemorrhagic Telangiectasia Type 2 | Primary Torsion Dystonia | Martsolf Syndrome | Multicystic Renal Dysplasia | Oculocutaneous Albinism Type 4 | Cataract | Cholelithiasis | Acute Generalized Exanthematous Pustulosis | Diffuse Mesangial Sclerosis | Cardiac Sarcoidosis | Cockayne Syndrome | Dental Caries | Vitelliform Macular Dystrophy | Histoplasmosis | Congenital Disorders Of Glycosylation | Mood Disorder | Xeroderma Pigmentosum Variant Type | Smith-Lemli-Opitz Syndrome | Dengue Hemorrhagic Fever | Carey-Fineman-Ziter Syndrome | Leiomyoma | Hydrops Fetalis