Holoprosencephaly

About the Disease
Holoprosencephaly, also known as holoprosencephaly sequence, is related to holoprosencephaly 9 and holoprosencephaly 7. An important gene associated with Holoprosencephaly is FGFR1 (Fibroblast Growth Factor Receptor 1), and among its related pathways/superpathways are Signal Transduction and Signaling by Hedgehog. Affiliated tissues include Primitive Streak, brain and eye, and related phenotypes are abnormal facial shape and holoprosencephaly

Common Targets
GLI2 | FAT1 | TGIF1 | SUFU | FGFR1 | SMC1A | PTCH1 | RAD21 | FGF8 | GAS1 | DISP1 | STIL | KMT2D | DLL1 | SHH | ZIC2 | SMC3 | PLCH1 | BOC | SIX3 | STAG2

Note: If you'd like to get a target analysis report for Holoprosencephaly, or if you are interested to learn how our AI-powered BDE-Chem can design therapeutic molecules to interact with the target(s) above against the disease of Holoprosencephaly at a cost 90% lower than traditional approaches, please feel free to contact us at BD@silexon.ai.

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