Extramammary Paget's Disease

About the Disease
Paget Disease, Extramammary, also known as extramammary paget disease, is related to scrotum paget's disease and adenocarcinoma in situ. An important gene associated with Paget Disease, Extramammary is KRT7 (Keratin 7), and among its related pathways/superpathways are Keratinization and COPI-independent Golgi-to-ER retrograde traffic. The drugs Petrolatum and Acetaminophen have been mentioned in the context of this disorder. Affiliated tissues include skin, lymph node and breast, and related phenotypes are neoplasm and eczematoid dermatitis

Common Targets
FGFR3 | PIK3CA | G999 | FGFR1 | G367 | G2064 | G3845 | FLT3 | RET | IDH2 | G672 | G7157 | DOT1L | ABL1 | MSH2 | MSH6 | G5728 | G1029 | PDGFRB | SMO | BRCA2 | LAMA5

Note: If you'd like to get a target analysis report for Extramammary Paget's Disease, or if you are interested to learn how our AI-powered BDE-Chem can design therapeutic molecules to interact with the target(s) above against the disease of Extramammary Paget's Disease at a cost 90% lower than traditional approaches, please feel free to contact us at BD@silexon.ai.

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