Cluster Headache

About the Disease
Cluster Headache, also known as headache, cluster, is related to headache and trigeminal neuralgia, and has symptoms including headache and recurrent paroxysmal headache. An important gene associated with Cluster Headache is HCRTR2 (Hypocretin Receptor 2), and among its related pathways/superpathways are Signal Transduction and GPCR downstream signalling. The drugs Zolmitriptan and Ketamine have been mentioned in the context of this disorder. Affiliated tissues include eye, pituitary and brain.

Common Targets
MTERF2 | HTR1A | CNR1 | Alpha-2 Adrenergic receptors (nonspecified subtype) | CRY2 | SLC6A2 | TRPV1 | GH1 | GNB3 | HTR2B | SLC22A3 | SSTR3 | Opioid receptor (nonspecified subtype) | VDR | LOC100507053 | HTR2A | ADH4 | HCRTR2 | Glycogen synthase kinase 3 (GSK-3) (nonspecified subtype) | CALCA | CALCRL | HRH1 | AGTR1 | HTR1B | Muscarinic Acetylcholine Receptor (mAChR) (nonspecified subtype) | 5-Hydroxytryptamine Receptor 2 (5-HT2) (nonspecified subtype) | Cyclooxygenase (COX) (nonspecified subtype) | HTR2C | SSTR5 | Nitric oxide synthase (NOS) (nonspecified subtype) | 5-Hydroxytryptamine Receptor (nonspecified subtype) | SSTR1 | CRY1 | HTR1D | CLOCK | MAPK8IP1 | CNR2 | SSTR2 | HFE

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