Neurofibromatosis

About the Disease
Neurofibromatosis, also known as neurofibromatoses, is related to acoustic neuroma and neurofibromatosis-noonan syndrome, and has symptoms including back pain, headache and pain. An important gene associated with Neurofibromatosis is NF1 (Neurofibromin 1), and among its related pathways/superpathways are Signal Transduction and Disease. The drugs Lidocaine and Methylphenidate have been mentioned in the context of this disorder. Affiliated tissues include spinal cord, skin and bone, and related phenotypes are Decreased viability and Decreased viability

Common Targets
FLT3 | NTRK1 | DHODH | G7422 | Matrix Metalloproteinase (MMP) (nonspecified subtype) | RET | G7157 | GSK3B | LZTR1 | LIMK2 | PDGFRA | KIT | Alkaline Phosphatase (ALP) (nonspecified subtype) | RAF1 | G673 | TTK | NF1 | PTPN11 | Transforming growth factor beta (nonspecified subtype) | ABL1 | CDK2/Cyclin A | PDGFRB | CSF1R | Cyclin A (nonspecified subtype) | SMARCB1 | ELANE | MSH6 | G7124 | CDK2 | IFNAR2 | SOS1 | KDR | DDR2 | FLT4 | Protein farnesyltransferase | FLT1 | SPRED1 | BCR | Serine/threonine-protein kinase (PAK) (nonspecified subtype)

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Other Diseases

Epithelioid Hemangioma | Rhinitis | Epidermolysis Bullosa | Hashimoto Thyroiditis | X-linked Sideroblastic Anemia | Creutzfeldt-Jakob Disease | Vertigo | Gout | Spinocerebellar Ataxia Type 14 | Nicotine Dependence | Graft-versus-host Disease | Demyelinating Diseases | Stroke | Carcinoma, Merkel Cell | Hyper IgE Syndrome | Hyperbilirubinemia, Neonatal | Rett Syndrome | Cystinosis | Spondylosis | Thyroiditis | Hemorrhage | Spondylometaphyseal Dysplasia | Fundus Albipunctatus | Hartsfield Syndrome | Spitzoid Melanoma | Leprosy | Eczema | Enhanced S-cone Syndrome | Lipid Metabolism Disorders | Congenital Heart Defects | Neuroblastoma | Holt-Oram Syndrome | Pineoblastoma | Desmosterolosis | Mesothelioma, Malignant | Pemphigoid | Epidermolytic Hyperkeratosis | Stuve-Wiedemann Syndrome | Enterocolitis, Necrotizing | Ovarian Hyperstimulation Syndrome | Heterotopic Ossification | Tyrosinemia Type 2 | Greig Cephalopolysyndactyly Syndrome | Lipoma | Hartnup Disease | Spondyloepiphyseal Dysplasia Tarda, X-linked | Brachydactyly | Hypoproteinemia, Hypercatabolic | Congestive Heart Failure | Hyperlipidemia | Woodhouse-Sakati Syndrome | Asphyxia Neonatorum | Macrophage Activation Syndrome | Apraxia | Esotropia | Alstrom Syndrome | Werner's Syndrome | Epicondylitis | Hyperthyroidism | Common Variable Immunodeficiency | Salla Disease | X-linked Acrogigantism | Borderline Personality Disorder | Sarcomatoid Carcinoma Of The Lung | Heavy Chain Disease | Cataract | Haim-Munk Syndrome | Lateral Meningocele Syndrome | Cerebellar Ataxia, Cayman Type | Retinal Vasculitis | Adrenal Insufficiency | Pain | Iron Overload | Bietti Crystalline Dystrophy | Cholestasis | Renal Hypouricemia | Bruck Syndrome | Paroxysmal Kinesigenic Dyskinesia | Pancreatitis | Hemochromatosis Type 1 | Hereditary Pyropoikilocytosis | Cockayne Syndrome | Porphyria, Acute Intermittent | Juvenile Myelomonocytic Leukemia | Cole-Carpenter Syndrome | Chloridorrhea, Congenital | Waardenburg Syndrome Type 2E | Congenital Dyserythropoietic Anemia Type 1 | Allergic Contact Dermatitis | Chronic Granulomatous Disease, X-linked | Constipation | Metanephric Adenoma | Congenital Dysfibrinogenemia | Inflammatory Myopathy | Maternally Inherited Diabetes And Deafness | Frontotemporal Dementia With Amyotrophic Lateral Sclerosis | Specific Granule Deficiency | Limb Girdle Muscular Dystrophy | Glycogen Storage Disease Type 1 | Ebstein Anomaly | Diabetes Insipidus, Neurogenic | Leukocyte Adhesion Deficiency | Papilledema | Basal Ganglia Disease, Biotin-responsive | Intracranial Hypertension | Tinea | Pfeiffer Syndrome | Acute Chest Syndrome | Sickle Cell Anemia | Okihiro Syndrome | Hereditary Inclusion Body Myopathy | Neuroectodermal Tumors, Primitive | Intracerebral Hemorrhage | Niemann-Pick Disease, Type A | Tuberculous Meningitis | Esophageal Carcinoma | Wilson's Disease | Diverticulitis | Asthma, Nocturnal | Dystonia Musculorum Deformans | Arthritis | Focal Cortical Dysplasia Type 2 | Glomerulonephritis, Membranoproliferative | Epidermolysis Bullosa Simplex With Mottled Pigmentation | Vascular Calcification | Dyslipidemia | C3 Glomerulonephritis | Combined Malonic And Methylmalonic Acidemia | Acromegaly | Polyneuropathy | Hepatic Veno-occlusive Disease | Tinea Versicolor | Galactosemia | Intestinal Pseudo-obstruction | Fibrosarcoma | Glomerulonephritis | Sitosterolemia | Mitochondrial DNA Depletion Syndrome, Myopathic Form | Vascular Cognitive Impairment | Familial Cerebral Amyloid Angiopathy | Cocaine-Related Disorders | Benign Familial Neonatal Convulsions | Alcoholism | Coloboma | Neurofibromatosis | Hepatitis A | Pycnodysostosis | Lymphedema | Cellulitis | Vitreoretinopathy, Proliferative | Inflammatory Myofibroblastic Tumor | Eclampsia | Hereditary Spherocytosis | Trichuriasis | Globozoospermia | Myopia | Alagille Syndrome | Alveolar Capillary Dysplasia | Sarcosinemia | Urolithiasis | Lymphangioma | Zimmermann-Laband Syndrome | Primary Pigmented Nodular Adrenocortical Disease | Diabetes Type 2 | Neurofibromatosis-Noonan Syndrome | Paraganglioma | Majeed Syndrome | Postaxial Polydactyly | Hypobetalipoproteinemias | Cenani-Lenz Syndactyly Syndrome | Myeloid Leukemia | Leukoplakia | Progressive Familial Intrahepatic Cholestasis Type 3 | Gilbert Syndrome | Guillain-Barre Syndrome | Heart Block | Amenorrhea | Poikiloderma With Neutropenia | Vogt-Koyanagi-Harada Syndrome | Waardenburg Syndrome Type 2 | Fucosidosis | Pulmonary Alveolar Proteinosis | GATA2 Deficiency | Renal Tubular Dysgenesis | Glaucoma, Congenital | Amyotrophic Lateral Sclerosis-parkinsonism-dementia Complex | Malnutrition | Cryptorchidism | Heart Failure | Myelofibrosis | McCune-Albright Syndrome | Chromosome 8q21.11 Deletion Syndrome | Spondyloepimetaphyseal Dysplasia With Joint Laxity, Type 3 | Pyruvate Decarboxylase Deficiency | Pulmonary Alveolar Microlithiasis | Chondrodysplasia Punctata | Plasma Cell Dyscrasia | Early Infantile Epileptic Encephalopathy 13 | Chronic Leukemia | Prolidase Deficiency | Retinoblastoma | Tic Disorder | Optic Neuropathy | Hepatitis, Autoimmune | Burn-McKeown Syndrome | Evans Syndrome | Split Hand-foot Malformation | Congenital Hereditary Endothelial Dystrophy Type II | Peripheral T-cell Lymphoma | Lichen Sclerosus | Keratitis-ichthyosis-deafness Syndrome | Parkinson's Disease | Hypermetropia | Central Core Disease | Takenouchi-Kosaki Syndrome | Primary Familial Brain Calcification | Vulvovaginitis | Angioedema, Hereditary | Osteogenesis Imperfecta Type II | Neutrophilia | Antisynthetase Syndrome | Amyloidosis | B-cell Prolymphocytic Leukemia | Isovaleric Acidemia | Systemic Lupus Erythematosus | Anosmia, Congenital | Familial Exudative Vitreoretinopathy | Fraser Syndrome | Sporadic Inclusion Body Myositis | Congenital Muscular Dystrophy | Chronic Enteropathy Associated With SLCO2A1 Gene | Loeys-Dietz Syndrome Type 4 | Sleep Disorder | Cardiomyopathy, Peripartum | Spinocerebellar Ataxia Type 7 | Infertility | Dysplastic Nevus | Rash | Measles | Leiomyoma | Leri Pleonosteosis | Blood Protein Disorders | Pendred Syndrome | Bardet-Biedl Syndrome | Pernicious Anemia | Hepatic Adenomatosis | Cyclic Vomiting Syndrome | Porphyria Cutanea Tarda | Meniere's Disease | Myopathy | Mabry Syndrome | Optic Neuropathy, Anterior Ischemic | Pseudohypoparathyroidism Type 2 | Intestinal Obstruction | Tyrosinemia | Achromatopsia | Lymphoproliferative Disorders | Pemphigus | Diabetic Neuropathy | Fatty Aldehyde Dehydrogenase Deficiency | Schnyder Crystalline Corneal Dystrophy | Periodontitis | Mohr-Tranebjaerg Syndrome | Pancreatitis, Chronic | Dyslexia | Jacobsen Syndrome | Azoospermia | Familial Hemiplegic Migraine | Leukemia | Acute Leukemia | Acrodysostosis | Polymyositis | Familial Hyperaldosteronism | Pulmonary Capillary Hemangiomatosis | Distal Spinal Muscular Atrophy | Klinefelter Syndrome | Schizoaffective Disorder | Sialidosis | Chediak-Higashi Syndrome | Heroin Dependence | Optic Atrophy 2 | Familial Male-limited Precocious Puberty | Microcephaly | Triphalangeal Thumb-polysyndactyly Syndrome | Macrodactyly | Charcot-Marie-Tooth Disease, Type 2 | Waldenstrom Macroglobulinemia | Malonyl-CoA Decarboxylase Deficiency | Trigonocephaly | Frontometaphyseal Dysplasia | Olmsted Syndrome | Antisocial Personality Disorder | Migraine | Glycogen Storage Disease Type 4 | Long-chain 3-hydroxyacyl-coenzyme A Dehydrogenase Deficiency | Anthrax | Kidney Stones | Cardiofaciocutaneous Syndrome | Multiple Sclerosis, Chronic Progressive | Glycogen Storage Disease Type 5 | Cold-induced Sweating Syndrome | Acute Kidney Injury | Autonomic Nervous System Disorders | Pityriasis Rubra Pilaris | Polycystic Kidney, Autosomal Dominant | Pulmonary Vein Stenosis | Purpura, Thrombotic Thrombocytopenic | Cancer, Lung | Nijmegen Breakage Syndrome | Congenital Disorders Of Glycosylation Type II | Congenital Disorders Of Glycosylation | Klippel-Feil Syndrome | Glycogen Storage Disease | Spinocerebellar Ataxia Type 10 | Neurogenic Bladder | Early Infantile Epileptic Encephalopathy 1 | X-linked Creatine Transporter Deficiency | Malaria, Cerebral | Wiedemann-Steiner Syndrome | Congenital Myasthenic Syndrome | 3-hydroxy-3-methylglutaric Aciduria | Geleophysic Dysplasia | Colitis | IgA Nephropathy | Hyperostosis | Metabolic Syndrome | Transient Bullous Dermolysis Of The Newborn | Chordoid Glioma | Interstitial Lung Diseases | Aneurysm, Abdominal Aortic | Hypotrichosis Simplex | Gastroschisis | Learning Disability | Swine Influenza | Fetal Akinesia Deformation Sequence | Kindler Syndrome | Riboflavin Transporter Deficiency Neuronopathy | Methemoglobinemia | C3 Glomerulopathy | Hypertrophic Osteoarthropathy, Primary, Autosomal Recessive 2 | Photosensitivity | Usher Syndrome Type IIC | Disseminated Superficial Actinic Porokeratosis | Hyperprolactinemia | Ehlers-Danlos Syndrome With Progressive Kyphoscoliosis, Myopathy, And Hearing Loss | Hyperlipidemia, Familial Combined | Pure Autonomic Failure | Hemophagocytic Lymphohistiocytosis | Iron Deficiency Anemia | Porphyria | Tendinitis | Motor Neuron Diseases | Diabetic Nephropathy | Vitelliform Macular Dystrophy | Multicentric Carpotarsal Osteolysis Syndrome | Acute Generalized Exanthematous Pustulosis | Cabezas Syndrome | Analgesia | Wolff-Parkinson-White Syndrome | Pneumothorax | Proteasome-associated Autoinflammatory Syndrome 2 | Osteochondroma | Pheochromocytoma | Myasthenia | Alpers Syndrome | Myoclonic Atonic Epilepsy | Periventricular Nodular Heterotopia | Narcolepsy | Esophageal Motility Disorders | Neurofibroma, Plexiform | Giant Axonal Neuropathy | Rheumatic Heart Disease | Herpes Genitalis | Sensory Ataxic Neuropathy, Dysarthria, And Ophthalmoparesis | Ameloblastic Carcinoma | Bullous Pemphigoid | Growth Hormone Excess | Skin Carcinoma | Fukuyama Congenital Muscular Dystrophy | Joubert Syndrome | Duchenne Muscular Dystrophy | Bone Giant Cell Tumor | Leukoencephalopathy, Progressive Multifocal | Endometritis | Rolandic Epilepsy | Pseudoachondroplasia | Glycogen Storage Disease Type 0, Muscle | Fibrodysplasia Ossificans Progressiva | Ichthyosis Hystrix, Curth-Macklin Type | Fibromyalgia | Holoprosencephaly | Chronic Mucocutaneous Candidiasis | Ganglioglioma | Parvovirus B19 Infection | Basan Syndrome | Delirium | Pseudohypoparathyroidism Type 1A | Hydrops Fetalis | Enlarged Vestibular Aqueduct | Congenital Absence Of Vas Deferens