Urolithiasis

About the Disease
Nephrolithiasis, Calcium Oxalate, also known as kidney stones, is related to nephrolithiasis/osteoporosis, hypophosphatemic, 1 and primary hyperoxaluria, and has symptoms including renal pain An important gene associated with Nephrolithiasis, Calcium Oxalate is SLC26A1 (Solute Carrier Family 26 Member 1), and among its related pathways/superpathways are Metabolism and Development_Hedgehog and PTH signaling pathways in bone and cartilage development. The drugs Nifedipine and Potassium citrate have been mentioned in the context of this disorder. Affiliated tissues include Kidney, bone and spinal cord, and related phenotypes are ureteropelvic junction obstruction and acute kidney injury

Common Targets
CASR | XDH | PTPN1 | Chymotrypsin (nonspecified subtype) | SLC22A12 | PDE5A | CES1 | ADRB3 | ADRB2 | Trypsin (nonspecified subtype) | HSPG2 | PON1 | Poly [ADP-ribose] polymerase (nonspecified subtype) | SOAT1 | RGS14 | ACE | KL | CLCN5 | G7124 | G3569 | MINDY4 | SPP1 | TRPV5 | VDR | IL1B | DGKH | ADRA1A | Phosphodiesterase 6 (PDE6) (nonspecified subtype) | G999 | G367

Note: If you'd like to get a target analysis report for Urolithiasis, or if you are interested to learn how our AI-powered BDE-Chem can design therapeutic molecules to interact with the target(s) above against the disease of Urolithiasis at a cost 90% lower than traditional approaches, please feel free to contact us at BD@silexon.ai.

Other Diseases

Rhabdoid Tumor | Systemic Mastocytosis | Iron Metabolism Disorders | Endometrial Hyperplasia | Duodenal Atresia | Optic Nerve Hypoplasia, Bilateral | Arteriosclerosis | Hypermetropia | Pelizaeus-Merzbacher Disease | Rett Syndrome | Epidermolytic Ichthyosis, Annular | Transcobalamin Deficiency | Sleep Apnea, Central | Hypoparathyroidism | Iron Overload | Language Disorders | Keratopathy | Communication Disorders | Astigmatism | Charcot-Marie-Tooth Disease Type 2D | Connective Tissue Disorders | Achromatopsia | Charcot-Marie-Tooth Disease Type 4B1 | Neurofibromatosis Type 1 | Desmosterolosis | Retinal Detachment | Rosacea | Angiosarcoma Of The Breast | Hermansky-Pudlak Syndrome | Osteoporosis | Charcot-Marie-Tooth Disease Type 2T | Facioscapulohumeral Muscular Dystrophy Type 1 | Cabezas Syndrome | Frontotemporal Dementia With Amyotrophic Lateral Sclerosis | Behavioral Variant Of Frontotemporal Dementia | Walker-Warburg Syndrome | Congenital Dyserythropoietic Anemia | Keratitis-ichthyosis-deafness Syndrome | Patent Ductus Arteriosus | Smith-Lemli-Opitz Syndrome | Wagner Disease | Fahr Disease | Paroxysmal Kinesigenic Dyskinesia | Osteitis | Hyperthyroidism | Myoclonus | Bardet-Biedl Syndrome | Syphilis | Myositis | Sick Sinus Syndrome | Pemphigus | Keratitis | Tremor | Mitochondrial Encephalomyopathy | Lamellar Ichthyosis | Interstitial Lung Diseases | Vasculitis | Hypotrichosis, Congenital, With Juvenile Macular Dystrophy | Neural Tube Defect | Alagille Syndrome | Lymphoma, AIDS-related | Temporal Lobe Epilepsy | Methylmalonic Acidemia | Hypoproteinemia, Hypercatabolic | Congenital Mirror Movements | Arts Syndrome | Spitzoid Melanoma | Conduct Disorder | Brooke-Spiegler Syndrome | Empyema | Galactosialidosis | Tinea Versicolor | Uveitis, Anterior | Heterotopic Ossification | Giant Cell Glioblastoma | Uremic Pruritus | Peyronie's Disease | Ophthalmia, Sympathetic | Hepatitis | Acrodermatitis | Shock, Cardiogenic | Congenital Afibrinogenemia | Hereditary Hemorrhagic Telangiectasia | Exocrine Pancreatic Insufficiency | Cerebellar Ataxia, Cayman Type | Myelodysplasia | Glycogen Storage Disease Type 1b | Blastoma, Pleuropulmonary | Ulcerative Colitis | Hydronephrosis | Microtia | Glycogen Storage Disease Type 1 | Ghosal Syndrome | Congenital Myopathy | Charcot-Marie-Tooth Disease, Type 1A | Marshall-Smith Syndrome | Glutaric Aciduria Type 1 | Lymphoma | Choriocarcinoma | Atopic Dermatitis | Renal Failure | Congenital Tufting Enteropathy | Chronic Inflammatory Demyelinating Polyneuropathy | Hepatic Veno-occlusive Disease | Asplenia | IgA Nephropathy | Trichomegaly | Hepatitis, Alcoholic | Episodic Ataxia | Lymphoma, B-cell | Hepatitis D | Erythema Nodosum | Cri-du-chat Syndrome | Familial Hypobetalipoproteinemia | Sjogren Syndrome | Chanarin-Dorfman Syndrome | B-cell Prolymphocytic Leukemia | CHARGE Syndrome | 3-methylglutaconic Aciduria Type I | Nephrotic Syndrome | Endometriosis | Retinitis Pigmentosa | Short-chain Acyl-CoA Dehydrogenase Deficiency | Osteogenesis Imperfecta Type III | Sorsby Fundus Dystrophy | Nijmegen Breakage Syndrome | Gynecomastia | Sensorineural Hearing Loss | Pneumoconiosis | Stroke, Hemorrhagic | Spinocerebellar Ataxia Type 42 | Pseudohermaphroditism | Takayasu's Arteritis | Charcot-Marie-Tooth Disease Type 4E | IgA Deficiency | Epidermolytic Hyperkeratosis | Cavitary Optic Disc Anomalies | Bethlem Myopathy | Neurofibromatosis-Noonan Syndrome | Onchocerciasis | Renal-hepatic-pancreatic Dysplasia | Keratoconjunctivitis | Hypothyroidism | Malaria, Cerebral | Mevalonate Kinase Deficiency | Joubert Syndrome 2 | Treacher Collins Syndrome | Hypophosphatemic Rickets With Hypercalciuria, Hereditary | Congenital Heart Defects | Cerebellofaciodental Syndrome | Primary Carnitine Deficiency | Progressive Osseous Heteroplasia | Sarcoma, Alveolar Soft Part | Orthostatic Intolerance | Nephronophthisis | Pernicious Anemia | Supravalvular Aortic Stenosis | Exotropia | Chronic Thromboembolic Pulmonary Hypertension | Long QT Syndrome Type 3 | Pulmonary Alveolar Proteinosis | Milk Allergy | Bietti Crystalline Dystrophy | Acute Coronary Syndrome | Obesity, Morbid | Feingold Syndrome | Tetraplegia | Paroxysmal Nocturnal Hemoglobinuria | Behcet's Disease | Cenani-Lenz Syndactyly Syndrome | Carcinoma, Merkel Cell | Pyruvate Carboxylase Deficiency Disease | Rolandic Epilepsy | Thyroiditis | Ellis-Van Creveld Syndrome | Fucosidosis | Liddle Syndrome | Esophagitis, Eosinophilic | Carpal Tunnel Syndrome | Hyperparathyroidism, Primary | Pseudohypoparathyroidism Type 1C | Nicotine Addiction | Rotor Syndrome | Chronic Granulomatous Disease, X-linked | Cantu Syndrome | Polymyalgia Rheumatica | Acute Leukemia | Charcot-Marie-Tooth Disease, Type 6 | Blepharophimosis Syndrome | Glutaric Aciduria Type 2 | Chromosome 5q Deletion Syndrome | Hairy Cell Leukemia | Meier-Gorlin Syndrome | Hypokalemic Periodic Paralysis | Adenosine Deaminase 2 Deficiency | Astrocytoma | Argininosuccinic Aciduria | Thyroid Dyshormonogenesis | Hypervalinemia | Delirium | Pigment Dispersion Syndrome | Benign Familial Infantile Seizures | Autosomal Recessive Bestrophinopathy | Epidermolysis Bullosa Dystrophica | Epilepsy | Thrombophilia | Scabies | Nemaline Myopathy 8 | Glioma | Still Disease | Fowler's Syndrome | Multiple Sclerosis | Huntington's Disease-like 2 | Spinal Muscular Atrophy Type 2 | Familial Male-limited Precocious Puberty | Multiple Congenital Anomalies-hypotonia-seizures Syndrome 2 | Cleidocranial Dysplasia | Arthritis, Psoriatic | Histiocytic Sarcoma | Diarrhea | Hyperuricemic Nephropathy, Familial Juvenile | GNE Myopathy | Microcephalic Osteodysplastic Primordial Dwarfism, Type I | Thanatophoric Dysplasia Type 1 | Familial Mediterranean Fever | Meningitis | Oculocutaneous Albinism | Vici Syndrome | Neurodevelopmental Disorder With Central Hypotonia And Dysmorphic Facies | Dyslipidemia | Bartter Syndrome | Atrial Septal Defect | Riboflavin Transporter Deficiency Neuronopathy | Sporadic Hemiplegic Migraine | Hyperparathyroidism | Psoriasis | Chloridorrhea, Congenital | Intellectual Disability, Autosomal Dominant 5 | Moyamoya Disease | Dysmorphophobia | Saethre-Chotzen Syndrome | Hypopigmentation | Tonsillitis | Esthesioneuroblastoma | Clouston Hidrotic Ectodermal Dysplasia | Necrobiosis Lipoidica | Smoldering Myeloma | Pyruvate Decarboxylase Deficiency | Acrodysostosis | Thyroiditis, Autoimmune | Fibromuscular Dysplasia | Wolfram Syndrome 2 | Encephalitis, Tick-borne | Persistent Truncus Arteriosus | Mucolipidosis Type III | Intestinal Pseudo-obstruction | Parkinson Disease 6, Autosomal Recessive Early-onset | Angiodysplasia | Bursitis | Vaginitis | Paraplegia | Osteopetrosis | Holoprosencephaly | Hartnup Disease | Long QT Syndrome Type 2 | Hemophilia | Prostatitis | Neuroblastoma | Epidermolytic Palmoplantar Keratoderma | Hepatitis, Autoimmune | Pulmonary Veno-occlusive Disease | Dysthymia | Epilepsy, Generalized | Infectious Diarrhea | Congenital Hemolytic Anemia | Tangier Disease | Maple Syrup Urine Disease | Thyroid Hormone Resistance | Larsen Syndrome | Scapuloperoneal Spinal Muscular Atrophy | Shprintzen-Goldberg Syndrome | Acute Lung Injury | Avian Influenza | Adenomatoid Tumor | Stiff-man Syndrome | 3-methylcrotonyl-CoA Carboxylase Deficiency | Non-Hodgkin Lymphoma | Peripheral Neuropathy | Congenital Hypofibrinogenemia | Charcot-Marie-Tooth Disease Type 4 | Charcot-Marie-Tooth Disease | Bipolar Disorder | Ocular Surface Squamous Neoplasia | Hemolytic Uremic Syndrome | Alpha-mannosidosis | Microcephalic Primordial Dwarfism | Leukemia | Sotos Syndrome | Viral Meningitis | Retinal Degeneration | Exostoses | Anorectal Malformations | Glycogen Storage Disease Type 4 | Oligoastrocytoma | Small Lymphocytic Lymphoma | Essential Fructosuria | Lyme Disease | Uterine Leiomyoma | Galactosemia | Compartment Syndrome | Epidermolysis Bullosa | Pelvic Inflammatory Disease | DRESS Syndrome | Mumps | PHARC Syndrome | Osteoporosis-pseudoglioma Syndrome | Leigh Syndrome | Anemia | Lymphedema | Dowling-Degos Disease | T-cell Leukemia | Insulin Resistance | Pancytopenia | Alstrom Syndrome | Porencephaly | Nicolaides-Baraitser Syndrome | Glycogen Storage Disease Type 1a | Leprosy | Cancer, Colon | Schizoaffective Disorder | Adams-Oliver Syndrome | Congenital Diaphragmatic Hernia | Multiple Hamartoma Syndrome | Pantothenate Kinase-associated Neurodegeneration | Congenital Generalized Lipodystrophy | Early Infantile Epileptic Encephalopathy 13 | MELAS Syndrome | Hyperlipidemia Type V | Ectodermal Dysplasia | Alveolar Capillary Dysplasia | Unverricht-Lundborg Syndrome | Cholestasis | Meckel-Gruber Syndrome | Atelosteogenesis Type 1 | Primary Ovarian Insufficiency | Lupus Erythematosus | Aldosterone Synthase Deficiency | Constipation | Rubinstein-Taybi Syndrome | Inflammatory Myofibroblastic Tumor | Creutzfeldt-Jakob Disease | Myoclonus-dystonia Syndrome | Hypertrophic Osteoarthropathy, Primary, Autosomal Recessive 2 | Presbycusis | Hyperkeratosis | Scleroderma, Diffuse | Hemochromatosis | Gastritis | Prolymphocytic Leukemia | Arthropathy | Postaxial Polydactyly | Thrombosis | Neurocysticercosis | Myotonic Disorders | Nail Disorder, Nonsyndromic Congenital | Odonto-onycho-dermal Dysplasia | Seizures-scoliosis-macrocephaly Syndrome | Encephalocele | Branchiootorenal Syndrome | Diabetes Type 1 | Acrodermatitis Enteropathica | Ependymoma | Sturge-Weber Syndrome | Lymphangioma | Cutaneous Lupus Erythematosus | Relapsing Polychondritis | CREST Syndrome | Hypohidrotic Ectodermal Dysplasia, X-linked | Hydrocephalus | Raynaud Phenomenon | LMNA-related Congenital Muscular Dystrophy | Pulmonary Sclerosing Hemangioma | Crouzon Syndrome With Acanthosis Nigricans | Hamartoma | Enlarged Vestibular Aqueduct | Perivascular Epithelioid Cell Tumor | Angioedema | Bullous Pemphigoid | Antley-Bixler Syndrome | Partington Syndrome | Hepatopulmonary Syndrome | Intracranial Hypertension | Primary Erythromelalgia | Renal Medullary Carcinoma | Deafness, Dystonia, And Cerebral Hypomyelination | Oligodendroglioma | Niemann-Pick Disease, Type A | Menetrier Disease | Dentinogenesis Imperfecta | Donnai-Barrow Syndrome