Disease

Cutaneous Lupus Erythematosus

About the Disease
Cutaneous Lupus Erythematosus, also known as lupus erythematosus, cutaneous, is related to subacute cutaneous lupus erythematosus and familial chilblain lupus, and has symptoms including exanthema and pruritus. An important gene associated with Cutaneous Lupus Erythematosus is CXCR3 (C-X-C Motif Chemokine Receptor 3), and among its related pathways/superpathways are Innate Immune System and Interferon gamma signaling. The drugs Hydroxychloroquine and Anti-Infective Agents have been mentioned in the context of this disorder. Affiliated tissues include skin, heart and t cells, and related phenotypes are immune system and hematopoietic system

Common Targets
TYK2 | PADI4 | KCNA3 | HLA-DQA1 | IFNA13 | G59272 | PPARG | RARA | CNR1 | KCND3 | TRPV1 | MSH5 | SYK | ABCA1 | G3605 | IRAK4 | LILRA4 | CLEC4C | STAT4 | G920 | G3569 | Retinoid acid receptor (nonspecified subtype) | PSORS1C1 | IFNG | JAK2 | TRIM39-RPP21 | SAMHD1 | JAK3 | JAK1 | IL4 | IFNAR1 | CSNK2B | STING1 | G7124 | KRR1 | GPR55 | Retinoid RXR receptor (nonspecified subtype) | TLR7 | TREX1 | RIPK1 | IFNAR2 | TLR8 | Phosphodiesterase IV (PDE4) (nonspecified subtype) | ELANE | CNR2

疾病靶点研报
Cutaneous Lupus Erythematosus

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Sandhoff Disease | Retinopathy, Diabetic | Hypogonadism | Oligospermia | Pseudohypoparathyroidism Type 1B | Leukoplakia, Oral | Cholelithiasis | X-linked Acrogigantism | Keratosis | Multicystic Renal Dysplasia | Brugada Syndrome 1 | Silver-Russell Syndrome | Parkinsonism | Currarino Syndrome | Charcot-Marie-Tooth Disease Type 2T | Takenouchi-Kosaki Syndrome | Histiocytosis | Hermansky-Pudlak Syndrome | Rheumatoid Arthritis | Stroke, Hemorrhagic | Sarcoidosis, Pulmonary | Dysgerminoma | SAPHO Syndrome | Cranioectodermal Dysplasia | Rhabdomyosarcoma | Bleeding Disorder Due To CalDAG-GEFI Deficiency | Nephrosclerosis | Spinocerebellar Ataxia Type 2 | Hashimoto Thyroiditis | Varices | Thyrotoxic Periodic Paralysis | POEMS Syndrome | Asthma | Spondylosis | Epidermolysis Bullosa Dystrophica | Pseudohermaphroditism | Congenital Afibrinogenemia | Spinocerebellar Ataxia Type 10 | Patent Foramen Ovale | Non-epidermolytic Palmoplantar Keratoderma | Arthritis, Gouty | Urethritis | Congenital 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