Disease

Myopathy

About the Disease
Myopathy, also known as muscular diseases, is related to bethlem myopathy 1 and batten-turner congenital myopathy, and has symptoms including back pain, leg cramps and muscle cramp. An important gene associated with Myopathy is RYR1 (Ryanodine Receptor 1), and among its related pathways/superpathways is Extracellular matrix organization. The drugs Sodium citrate and Prednisolone phosphate have been mentioned in the context of this disorder. Affiliated tissues include Placenta, skeletal muscle and bone, and related phenotypes are muscle and growth/size/body region

Common Targets
TARDBP | TPM3 | HLA-A | ORAI1 | FBXO34 | TNPO3 | ATP6V0E1 | MTM1 | FLNC | MEGF10 | CDCP1 | VMA21 | FXR1 | SELENON | ANO5 | TRNW | HNRNPA1 | ND1 | PPARD | MIR489 | CLN3 | LEP | DNA2 | ERICH1 | RASGRF2 | CHCHD10 | TWNK | RYR2 | KY | SCN4A | SLC15A1 | GFPT1 | DNM2 | TNNT1 | STAC3 | USP14 | CYP3A5 | POLG | SLC25A3 | MYPN | ADSS1 | BSCL2 | TK2 | EPG5 | CYP2R1 | TRAPPC11 | LDB3 | CLCN1 | MYH2 | MATR3 | SMPD2 | HSPB8 | LILRB2 | SYNM | FDX2 | DNAJB6 | STIM1 | BIN1 | MFN2 | TTN | FHL1 | TARS2 | CYP2C9 | TRNA | CHKB | ACTG2 | MICU1 | SLCO1B1 | COL6A1 | PNPLA2 | HLA-C | VCP | CFH | MSTN | EHMT2 | HACD1 | CNTN1 | TNXB | COL6A2 | SIRT5 | HLA-DRB1 | UNC45B | TRNK | ACTA1 | ALG14 | G4780 | ND5 | CFL2 | MYH7 | PDE4D | COL6A3 | GIPC1 | HLA-B | VARS2 | SLCO1A2 | G5243 | MYBPC1 | NEFL | SLC30A4-AS1 | CYP3A4 | SLCO1B3 | TPM2 | PGK1 | NARS2 | CAV3 | LILRB5 | PAX7 | CCDC78 | NEB | DES | MYBPC3 | NPAP1 | COQ2 | SVIL | CETP | CKM | NOTCH2NLC | COX6A2 | RYR1 | TUBB3 | TRNN | SBDS | G9429 | GNE | VDR | CASQ1 | PYROXD1 | AMPD1

疾病靶点研报
Myopathy

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