Autosomal Recessive 1 Primary Hypertrophic Osteoarthropathy

About the Disease
Hypertrophic Osteoarthropathy, Primary, Autosomal Recessive, 1, also known as cranioosteoarthropathy, is related to acromegaloid changes, cutis verticis gyrata, and corneal leukoma and primary hypertrophic osteoarthropathy, and has symptoms including arthralgia, flushing and metatarsalgia. An important gene associated with Hypertrophic Osteoarthropathy, Primary, Autosomal Recessive, 1 is HPGD (15-Hydroxyprostaglandin Dehydrogenase). The drugs Etoricoxib and Cyclooxygenase Inhibitors have been mentioned in the context of this disorder. Affiliated tissues include bone, skin and heart, and related phenotypes are abnormal cortical bone morphology and large fontanelles

Common Targets
HPGD | SLCO2A1

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