IgA Deficiency

About the Disease
Immunoglobulin Alpha Deficiency, also known as iga deficiency, is related to primary agammaglobulinemia and immunoglobulin g deficiency. An important gene associated with Immunoglobulin Alpha Deficiency is TNFRSF13B (TNF Receptor Superfamily Member 13B), and among its related pathways/superpathways are Akt Signaling and PAK Pathway. The drug Immunoglobulin A has been mentioned in the context of this disorder. Affiliated tissues include bone marrow, t cells and b cells, and related phenotypes are no effect and no effect

Common Targets
RAD50

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Eosinophilic Asthma | Hyperparathyroidism-jaw Tumor Syndrome | Uveitis, Anterior | Glycogen Storage Disease | Chondromyxoid Fibroma | Acute Lung Injury | Hemorrhage | Congenital Tufting Enteropathy | Peutz-Jeghers Syndrome | Cataract | Gout | Pendred Syndrome | Optic Nerve Diseases | Retinopathy Of Prematurity | Congenital Lipoid Adrenal Hyperplasia | Schizoaffective Disorder | Autosomal Recessive Bestrophinopathy | Spondylosis | Coronary Heart Disease | Analgesia | Metabolic Syndrome | Scleroderma | Phenylketonuria | Glucagonoma | Gitelman Syndrome | Ependymoma | Leber Hereditary Optic Neuropathy | Pneumonia, Bacterial | Hereditary Folate Malabsorption | Ichthyosis, X-linked | Lattice Corneal Dystrophy | Premature Ejaculation | Tetanus | Blepharitis | Paraganglioma | Inflammatory Linear Verrucous Epidermal Nevus | Epidermolytic Ichthyosis, Annular | Tetraplegia | C3 Glomerulopathy | Rheumatoid Arthritis | Hypertrophy | Mevalonate Kinase Deficiency | Adenylosuccinate Lyase Deficiency | Persistent Hyperplastic Primary Vitreous | Neuroectodermal Tumors, Primitive | Idiopathic Pulmonary Fibrosis | Coma | Hepatic Steatosis | Arrhythmogenic Right Ventricular Cardiomyopathy | Renal Tubular Dysgenesis | Melanoma, Malignant | Encephalopathy | Pulmonary Sclerosing Hemangioma | Onchocerciasis | Antenatal Bartter Syndrome Type 1 | Hypothalamic Obesity | Medium-chain Acyl-CoA Dehydrogenase Deficiency | Jalili Syndrome | Gaucher Disease | Retinal Detachment | Cystitis, Interstitial | Primary Progressive Nonfluent Aphasia | 5-oxoprolinase Deficiency | Congenital Disorders Of Glycosylation Type II | Migraine | Androgen Insensitivity | Carey-Fineman-Ziter Syndrome | Turner's Syndrome | Obesity, Morbid | Oligospermia | Immunoproliferative Disorders | Tangier Disease | Ophthalmoplegia | Pericarditis | Ocular Surface Squamous Neoplasia | Netherton Syndrome | Cole-Carpenter Syndrome | Hyperbilirubinemia, Neonatal | Asthma, Exercise-induced | Atrial Septal Defect | Angiomyolipoma | Noonan Syndrome-like Disorder With Loose Anagen Hair | VEXAS Syndrome | Glycogen Storage Disease Type 3 | Lipid Storage Myopathy | Ophthalmia, Sympathetic | NDH Syndrome | HANAC Syndrome | Atopic Dermatitis | Epidermolysis Bullosa Simplex, Localized | Central Pain Syndrome | Ulcerative Colitis | Heimler Syndrome | Thrombophlebitis | MELAS Syndrome | Mesial Temporal Lobe Epilepsy With Hippocampal Sclerosis | Hyperekplexia | Spinocerebellar Ataxia Type 3 | Blepharospasm | Camptocormia | Antley-Bixler Syndrome | Myositis, Focal | Deafness, Dystonia, And Cerebral Hypomyelination | Non-small Cell Lung Cancer | 3-M Syndrome | Cardiomyopathy, Restrictive | Focal Segmental Glomerulosclerosis | Dysequilibrium Syndrome | Genitopatellar Syndrome | Cardiomyopathy, Hypertrophic | Graves Disease | Polymicrogyria | Hemoglobinopathies | Sarcoma, Alveolar Soft Part | Esophageal Motility Disorders | Genee-Wiedemann Syndrome | Cancer, Brain | Kabuki Syndrome | Metanephric Adenoma | Congestive Heart Failure | Smith-Lemli-Opitz Syndrome | Sotos Syndrome | Zellweger Syndrome | Waardenburg Syndrome Type 4 | Silver-Russell Syndrome | REM Sleep Behavior Disorder | Early Infantile Epileptic Encephalopathy | Waardenburg Syndrome Type 4A | Ganglioneuroma | Hyperkeratosis | Coloboma | Heterotopic Ossification | Sweet Syndrome | Brachial Plexus Neuropathy | Thanatophoric Dysplasia Type 1 | Multicystic Renal Dysplasia | Smith-Kingsmore Syndrome | Renal Dysplasia | Glomerulonephritis, Membranous | T-cell Chronic Lymphocytic Leukemia | Acute Leukemia | Fraser Syndrome | Spondylo-ocular Syndrome | Hepatitis C, Chronic | 3-methylglutaconic Aciduria Type I | Sturge-Weber Syndrome | Blomstrand Osteochondrodysplasia | Hypokalemia | Wolfram Syndrome 2 | Hypoglycemia | Trachoma | Irritable Bowel Syndrome | Nijmegen Breakage Syndrome | Goiter, Nodular | Restrictive Dermopathy | Bone Giant Cell Tumor | Temtamy Preaxial Brachydactyly Syndrome | Neuromuscular Disorders | Perry Syndrome | Nephronophthisis | Stomatitis | Disseminated Intravascular Coagulation | Spinocerebellar Ataxia | Sleep Apnea, Obstructive | Antisocial Personality Disorder | Pachyonychia Congenita | Systemic Lupus Erythematosus | Metachromatic Leukodystrophy | Learning Disability | 3-hydroxyacyl-CoA Dehydrogenase Deficiency | Oculodentodigital Dysplasia | Cavitary Optic Disc Anomalies | Papilloma | Hyperandrogenemia | Familial Isolated Hyperparathyroidism | Hyperuricemic Nephropathy, Familial Juvenile | Hemangioblastoma | Diarrhea | Osteogenesis Imperfecta Type VI | Haim-Munk Syndrome | Schwartz-Jampel-Aberfeld Syndrome | Diabetes Type 1 | Ataxia-hypogonadism-choroidal Dystrophy Syndrome | Multisystemic Smooth Muscle Dysfunction Syndrome | Lupus Erythematosus | Nasodigitoacoustic Syndrome | Frank-ter Haar Syndrome | Anxiety Disorders | Epidermolytic Palmoplantar Keratoderma | Glaucoma, Congenital | Endocarditis | Spina Bifida | Familial Hemiplegic Migraine | Epidermolysis Bullosa Simplex | Aarskog-Scott Syndrome | Amblyopia | Aldosterone Deficiency | Retinal Coloboma | Leprosy | Meningeal Melanocytoma | Hyperferritinemia-cataract Syndrome | Hypomyelination With Atrophy Of Basal Ganglia And Cerebellum | Kaposi Sarcoma | Hereditary Sensory Neuropathy Type 1 | Hypertension, Renal | Tardive Dyskinesia | Frontotemporal Dementia | Alexander Disease | Waldenstrom Macroglobulinemia | DNA Ligase IV Deficiency | Leiomyosarcoma | Osteochondrosis | Creutzfeldt-Jakob Disease | Acne | Cancer, Prostate | Bronchitis, Chronic | Chorea | Crisponi Syndrome | Christianson Syndrome | Porphyria, Acute Intermittent | Fatty Aldehyde Dehydrogenase Deficiency | Carbamoyl Phosphate Synthetase I Deficiency | Infantile Nephropathic Cystinosis | Melanocytic Nevus | Acne Vulgaris | Cystitis | Lewy Body Dementia | Primary Ovarian Insufficiency | Subacute Sclerosing Panencephalitis | Cerebellofaciodental Syndrome | Congenital Stromal Corneal Dystrophy | Osteoglophonic Dysplasia | Vasculitis | Hyperphenylalaninemia | 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